Effects of benzo[ a]pyrene exposure on a fish population resistant to the toxic effects of dioxin-like compounds

• Published in: Aquatic toxicology Vol. 57; no. 4; pp. 203 - 215
• Main Authors: Nacci, Diane E, Kohan, Michael, Pelletier, Marguerite, George, Elizabeth
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.06.2002; Elsevier Science
• Subjects: Adaptation, Physiological; Agnatha. Pisces; Animal, plant and microbial ecology; Animals; Applied ecology; Aryl hydrocarbon receptor; Benzo(a)pyrene - toxicity; Benzo[ a]pyrene; Biological and medical sciences; Cytochrome P-450 CYP1A1 - drug effects; Cytochrome P-450 CYP1A1 - metabolism; Dioxins - toxicity; DNA adducts; DNA Adducts - metabolism; Ecotoxicology, biological effects of pollution; Effects of pollution and side effects of pesticides on vertebrates; Environmental Pollutants - toxicity; Female; Fundamental and applied biological sciences. Psychology; Fundulidae - genetics; Fundulidae - metabolism; Fundulidae - physiology; Fundulus heteroclitus; Liver - enzymology; Male; Pisces; Polychlorinated Biphenyls - toxicity; Receptors, Aryl Hydrocarbon - metabolism; Sex Factors; Tissue Distribution; Xenobiotic resistance; Xenobiotics - metabolism; United States; North America; America; Benzo[ a]pyrene; Aryl hydrocarbon receptor; DNA adducts; Xenobiotic resistance; Brackish water environment; Toxicity; Estuaries; Exposure; Wild animal; Polycyclic aromatic compound; Experimental study; Spatial variation; Fundulus heteroclitus; Ah receptor; Vertebrata; Sensitivity resistance; Pisces; DNA; Water pollution; Molecular adduct; Xenobiotic; Adaptation

Effects of a model polycyclic aromatic hydrocarbon (PAH) were compared in populations of the estuarine fish Fundulus heteroclitus indigenous to a reference site and one highly contaminated with polychlorinated biphenyls (PCBs) and other compounds. The fish population resident to the PCB-contaminated...