LC–MS-based quantitation of proteomic changes induced by Norcantharidin in MTB-Treated macrophages

• Published in: Proteome science Vol. 22; no. 1; pp. 13 - 10
• Main Authors: Wu, Yi-Lin, Li, Yuan-Ting, Liu, Gan-Bin, Wu, Jin-Lin, Liu, Xiao-Ran, Gao, Xin-Xuan, Huang, Qi-Dan, Liang, Jin, Ouyang, Jia-Yi, Ding, Yi-Ran, Wu, Jun-Yi, Lu, Yuan-Bin, Gao, Yu-Chi, Cai, Xiao-Zhen, Zhang, Jun-Ai
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 04.12.2024; BioMed Central; BMC
• Subjects: BCG; BCG vaccines; Chromatin; Drug resistance in microorganisms; Enzymes; G proteins; H37Ra; Immunotherapy; Liquid chromatography; Macrophage; Macrophages; Mycobacterium tuberculosis; Norcantharidin; Patient compliance; Proteome; T cells; Tuberculosis; United States; China; Proteome; Mycobacterium tuberculosis; H37Ra; Norcantharidin; Macrophage

Tuberculosis drug resistance contributes to the spread of tuberculosis. Immunotherapy is an effective strategy for treating tuberculosis, with the regulation of macrophage-mediated anti-tuberculosis immunity being crucial. Norcantharidin (NCTD), a drug used in tumor immunotherapy, has significant im...