MicroRNA-127 Promotes Anti-microbial Host Defense through Restricting A20-Mediated De-ubiquitination of STAT3

• Published in: iScience Vol. 23; no. 1; p. 100763
• Main Authors: Liu, Xiaoyi, Mao, Yun, Kang, Yanhua, He, Long, Zhu, Bo, Zhang, Wei, Lu, Yin, Wu, Qinan, Xu, Dakang, Shi, Liyun
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 24.01.2020; Elsevier
• Subjects: Bacteriology; Immunology; Microbiology; Molecular Mechanism of Behavior; Immunology; Molecular Mechanism of Behavior; Microbiology; Bacteriology

The increasing rising of multiple drug-resistant Staphylococcus aureus has become a major public health concern, underscoring a pressing need for developing therapies essentially based on the understanding of host defensive mechanism. In the present study, we showed that microRNA (miR)-127 played a...