Photoactive nanocatalysts as DTT-assisted BSA-AuNCs with enhanced oxidase-mimicking ability for sensitive fluorometric detection of antioxidants

• Published in: Journal of nanobiotechnology Vol. 22; no. 1; pp. 585 - 15
• Main Authors: Swain, Sanskruti, Lin, Ting-Yi, Chou, I-Hsuan, Liu, Shu-Chen, Mallick, Bikash C., Lin, Hsing-Ying, Huang, Chen-Han
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 28.09.2024; BioMed Central; BMC
• Subjects: Animals; Antioxidants; Antioxidants - chemistry; Antioxidants - pharmacology; Ascorbic Acid - chemistry; Biochemical assays; Catalysis; Catalysts; Chemical properties; Dithiothreitol - chemistry; DTT@BSA-AuNCs; Fluorescence; Fluorimetry; Fluorometry - methods; Glutathione - chemistry; Glutathione - metabolism; Gold; Gold - chemistry; Humans; Limit of Detection; Measurement; Metal Nanoparticles - chemistry; Methods; Nanoparticles; Oxidase-like nanozymes; Oxidation-Reduction; Oxidative Stress - drug effects; Oxidoreductases - chemistry; Oxidoreductases - metabolism; Photocatalysis; Saliva - chemistry; Serum albumin; Serum Albumin, Bovine - chemistry; Israel; Antioxidants; Fluorescence; Photocatalysis; DTT@BSA-AuNCs; Oxidase-like nanozymes

Redox imbalance and oxidative stress are increasingly recognized as significant factors in health disorders such as neurodegenerative disorders, premature aging and cancer. However, detecting antioxidant levels that is crucial for managing oxidative stress, can be challenging due to existing assays&...