Room for improvement in capturing cancer family history in a gynecologic oncology outpatient setting

• Published in: Gynecologic oncology reports Vol. 40; p. 100941
• Main Authors: Lin, Jenny, Wolfe, Isabel, Ahsan, Muhammad Danyal, Krinsky, Hannah, Lackner, Andreas I., Pelt, Joe, Bolouvi, Karen, Gamble, Charlotte, Thomas, Charlene, Christos, Paul J., Cantillo, Evelyn, Holcomb, Kevin, Chapman-Davis, Eloise, Sharaf, Ravi, Lipkin, Steven M., Blank, Stephanie V., Frey, Melissa K.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.04.2022; Elsevier
• Subjects: Cancer family history; Genetic testing; Medical history taking; Medical records; Pedigree; Short Communication; Medical records; Genetic testing; Pedigree; Medical history taking; Cancer family history
• ISSN: 2352-5789; 2352-5789
• DOI: 10.1016/j.gore.2022.100941

•Collection of family health history is necessary for identifying patients at risk for hereditary cancer.•Patients with either a relative with cancer or prior genetic testing provided a more comprehensive family health history.•Family health history often lacks key elements for comprehensive cancer risk assessment. The literature demonstrates that the quality of cancer family history (CFH) as currently collected in the outpatient setting is inadequate to assess disease risk. Prior to implementation of a web-based application for cancer family history collection, we aimed to review the quality of collected CFH in a gynecologic oncology outpatient clinic and determine contributing patient factors. Medical records were reviewed for 200 new patients presenting between 4/2019–7/2019. CFH was collected during the patient interview and evaluated for inclusion of eight elements based on standards set by the genetics community. Univariate and multivariable linear regression analyses were utilized to evaluate the effect of patient characteristics on the number of relatives included in the CFH. Among our cohort of 200 patients, CFH was documented for 185 patients (92.5%). On univariate analysis, patients with a family history of cancer and prior genetic testing had significantly greater median number of relatives included in the CFH. On multivariable analysis, patients with family members with cancer had significantly more relatives included. Our data are consistent with the literature, suggesting that the current collection methods may not adequately capture all measures of a high quality CFH. Patients reporting no family history of cancer and those without prior genetic testing were least likely to have CFH that included key quality elements and these patients might benefit from health information technology CFH collection tools.