A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response - Adamson, Britt; Norman, Thomas M.; Jost, Marco; Cho, Min Y.; Nuñez, James K.; Chen, Yuwen; Villalta, Jacqueline E.; Gilbert, Luke A.; Horlbeck, Max A.; Hein, Marco Y.; Pak, Ryan A.; Gray, Andrew N.; et al. (Cell, 2016)
Keywords: Animals; cell-to-cell heterogeneity; Clustered Regularly Interspaced Short Palindromic Repeats; CRIPSRi; CRISPR; Endoribonucleases; Feedback; genome-scale screening; Humans; Models, Molecular; Protein Serine-Threonine Kinases; RNA, Guide, CRISPR-Cas Systems - metabolism; Sequence Analysis, RNA - methods; Single-Cell Analysis - methods; single-cell genomics; Single-cell RNA-seq; Transcription, Genetic; Unfolded Protein Response; CRISPR; unfolded protein response; Single-cell RNA-seq; cell-to-cell heterogeneity; single-cell genomics; genome-scale screening; CRIPSRi