Progesterone loaded thermosensitive hydrogel for vaginal application: Formulation and in vitro comparison with commercial product

• Published in: Saudi pharmaceutical journal Vol. 27; no. 8; pp. 1096 - 1106
• Main Authors: Velázquez, Natalia S., Turino, Ludmila N., Luna, Julio A., Mengatto, Luciano N.
• Format: Journal Article
• Language: English
• Published: Saudi Arabia Elsevier B.V 01.12.2019; Elsevier
• Subjects: Drug delivery; In vitro diffusion; Inclusion complexes; Methylated-β-cyclodextrin; Original; Progesterone; Inclusion complexes; Drug delivery; Progesterone; Methylated-β-cyclodextrin; In vitro diffusion

Progesterone (PGT) is a natural hormone that stimulates and regulates various important functions, such as the preparation of the female body for conception and pregnancy. Due to its low water solubility, it is administered in a micronized form and/or in vehicles with specific solvents requirements....