Relationship between Human Immunodeficiency Type 1 Infection and Expression of Human APOBEC3G and APOBEC3F

• Published in: The Journal of infectious diseases Vol. 198; no. 4; pp. 486 - 492
• Main Authors: Ulenga, Nzovu K, Sarr, Abdoulaye Dieng, Thakore-Meloni, Seema, Sankalé, Jean-Louis, Eisen, Geoff, Kanki, Phyllis J
• Format: Journal Article
• Language: English
• Published: Chicago, IL The University of Chicago Press 15.08.2008; University of Chicago Press
• Subjects: Adult; AIDS; Antivirals; APOBEC-3G Deaminase; Biological and medical sciences; Cytidine Deaminase - genetics; Cytidine Deaminase - metabolism; Cytosine Deaminase - genetics; Cytosine Deaminase - metabolism; Female; Fundamental and applied biological sciences. Psychology; HIV 1; HIV Infections - immunology; HIV Infections - metabolism; HIV-1 - pathogenicity; HIV-1 - physiology; HIV/AIDS; Human immunodeficiency virus 1; Human viral diseases; Humans; Infections; Infectious diseases; Integration host factors; Medical sciences; Messenger RNA; Microbiology; Point groups; RNA, Messenger - analysis; Test ranges; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Viral Load; Viremia; Viruses; Human; Infection; Immunopathology; Microbiology; Viral disease; AIDS; Immune deficiency

Background. Human immunodeficiency virus type 1 (HIV-1)-infected individuals with a high viral set point progress to acquired immunodeficiency syndrome (AIDS) more rapidly than those with a low viral set point. It is not entirely clear which host and viral factors are responsible for the viral set p...