Multi-Tissue Acceleration of the Mitochondrial Phosphoenolpyruvate Cycle Improves Whole-Body Metabolic Health - Abulizi, Abudukadier; Cardone, Rebecca L.; Stark, Romana; Lewandowski, Sophie L.; Zhao, Xiaojian; Hillion, Joelle; Ma, Lingjun; Sehgal, Raghav; Alves, Tiago C.; Thomas, Craig; Kung, Charles; Wang, Bei; et al. (Cell metabolism, 2020)
Keywords: anaplerosis; Animals; cataplerosis; fatty liver; Homeostasis; human islets; Insulin - metabolism; insulin resistance; insulin secretion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria - metabolism; mitochondrial GTP; mitochondrial PEPCK; Phosphoenolpyruvate - metabolism; phosphoenolpyruvate cycle; pyruvate kinase; Pyruvate Kinase - metabolism; Rats; Rats, Sprague-Dawley; human islets; anaplerosis; pyruvate kinase; cataplerosis; mitochondrial GTP; fatty liver; insulin secretion; mitochondrial PEPCK; phosphoenolpyruvate cycle; insulin resistance