In experimental peripheral arterial disease, type 2 diabetes alters post-ischemic gene expression

• Published in: Journal of clinical & translational endocrinology Vol. 17; p. 100199
• Main Authors: Peravali, Rahul, Gunnels, Lucas, Dhanabalan, Karthik, Ariganjoye, Folabi, Gerling, Ivan C., Dokun, Ayotunde O.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.09.2019; Elsevier
• Subjects: Genome-wide gene expression profiling; Molecular pathway analysis; Peripheral artery disease; Research Paper; Type 2 diabetes mellitus; Peripheral artery disease; Type 2 diabetes mellitus; Molecular pathway analysis; Genome-wide gene expression profiling

Peripheral arterial disease is characterized by impaired blood flow to tissues outside the heart due to atherosclerosis and it most frequently occurs in the lower extremities. Type 2 diabetes (T2D) is a well-known risk factor that accelerate the course and contributes to poor clinical outcomes of PA...