IL-17-producing peripheral blood CD177+ neutrophils increase in allergic asthmatic subjects

• Published in: Allergy, asthma, and clinical immunology Vol. 9; no. 1; p. 23
• Main Authors: Ramirez-Velazquez, Carlos, Castillo, Elena Cristina, Guido-Bayardo, Leopoldo, Ortiz-Navarrete, Vianney
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 03.07.2013; BioMed Central
• Subjects: Allergy; Asthma; Development and progression; Interleukins; Neutrophils; Physiological aspects; Testing

A T helper cell (TH) 17-biased response has been observed in patients with allergic asthma, particularly in those with neutrophil accumulation in the lung. Therefore, we sought to test the hypothesis that neutrophils might be an important source of interleukin (IL)-17 in allergic asthma. Whole perip...