The Cytoplasmic Actins in the Regulation of Endothelial Cell Function

• Published in: International journal of molecular sciences Vol. 22; no. 15; p. 7836
• Main Authors: Dugina, Vera B., Shagieva, Galina S., Shakhov, Anton S., Alieva, Irina B.
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 22.07.2021; MDPI
• Subjects: Actin; Blood circulation; Blood vessels; Cell cycle; Cell division; Contraction; Cytoplasm; Cytoskeleton; endothelial barrier function; endothelial cell; Endothelial cells; Endothelium; Fibroblasts; Isoforms; Microscopy; Motility; Muscles; non-muscle actin isoforms; Organs; Pathogenesis; Permeability; Polymerization; Proteins; Pulmonary arteries; Review; Signal transduction; Smooth muscle; β-actin; γ-actin

The primary function of the endothelial cells (EC) lining the inner surface of all vessels is to regulate permeability of vascular walls and to control exchange between circulating blood and tissue fluids of organs. The EC actin cytoskeleton plays a crucial role in maintaining endothelial barrier fu...