New Azaphilones from Nigrospora oryzae Co-Cultured with Beauveria bassiana

• Published in: Molecules (Basel, Switzerland) Vol. 23; no. 7; p. 1816
• Main Authors: Zhang, Zhuo-Xi, Yang, Xue-Qiong, Zhou, Qing-Yan, Wang, Bang-Yan, Hu, Ming, Yang, Ya-Bin, Zhou, Hao, Ding, Zhong-Tao
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.07.2018; MDPI
• Subjects: antifungal selectivity; azaphilone; Beauveria bassiana; Carbon; co-culture; Conflicts of interest; Cotton; Experiments; Fungi; Hydrogenation; Metabolism; Metabolites; Natural products; Nigrospora oryzae; NO inhibitory activity; Spectrum analysis; China; Nigrospora oryzae; Beauveria bassiana; NO inhibitory activity; antifungal selectivity; azaphilone; co-culture

In this study, the co-culture of Nigrospora oryzae and Beauveria bassiana, the endophytes in the seeds of Dendrobium officinale, were examined for metabolite diversity. Five new azaphilones were isolated, and their structures were determined by spectral analysis. In terms of azaphilones, compound 2...