Amphiphilic poly(l-amino acids) — New materials for drug delivery
The formulation of drug compounds into medicines will increasingly rely on the use of specially tailored molecules, which fundamentally alter the drug's pharmacokinetics to enable its therapeutic activity. This is particularly true of the more challenging hydrophobic drugs or therapeutic biolog...
Saved in:
| Published in | Journal of controlled release Vol. 161; no. 2; pp. 523 - 536 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Netherlands
Elsevier B.V
20.07.2012
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The formulation of drug compounds into medicines will increasingly rely on the use of specially tailored molecules, which fundamentally alter the drug's pharmacokinetics to enable its therapeutic activity. This is particularly true of the more challenging hydrophobic drugs or therapeutic biological molecules. The demand for such enabled medicines will translate into a demand for advanced highly functionalised drug delivery materials. Polymers have been used to formulate medicines for many decades and this is unlikely to change soon. Amphiphilic polymers based on amino acids are the subject of this review. These molecules, which present as either poly(l-amino acid) block copolymers or poly(l‐amino acid) backbones with hydrophobic substituents, self assemble into micelles, vesicles, nanofibres and solid nanoparticles and such self assemblies, have drug delivery capabilities. The nature of the self-assembly depends on the chemistry of the constituent molecules, with the more hydrophilic molecules forming nanosized micellar aggregates including peptide nanofibres, molecules of intermediate hydrophobicity forming polymeric vesicles and the more hydrophobic variants forming amorphous polymeric nanoparticles of 100–1000nm in diameter. The self-assemblies may be loaded with drugs or may present as micelle forming polymer–drug conjugates and the supramolecular aggregates have been employed as drug solubilisers, tumour targeting agents, gene delivery vectors and facilitators of intracellular drug uptake, with a more promising polymer–drug conjugate progressing to clinical testing.
[Display omitted] |
|---|---|
| AbstractList | The formulation of drug compounds into medicines will increasingly rely on the use of specially tailored molecules, which fundamentally alter the drug's pharmacokinetics to enable its therapeutic activity. This is particularly true of the more challenging hydrophobic drugs or therapeutic biological molecules. The demand for such enabled medicines will translate into a demand for advanced highly functionalised drug delivery materials. Polymers have been used to formulate medicines for many decades and this is unlikely to change soon. Amphiphilic polymers based on amino acids are the subject of this review. These molecules, which present as either poly(l-amino acid) block copolymers or poly(laamino acid) backbones with hydrophobic substituents, self assemble into micelles, vesicles, nanofibres and solid nanoparticles and such self assemblies, have drug delivery capabilities. The nature of the self-assembly depends on the chemistry of the constituent molecules, with the more hydrophilic molecules forming nanosized micellar aggregates including peptide nanofibres, molecules of intermediate hydrophobicity forming polymeric vesicles and the more hydrophobic variants forming amorphous polymeric nanoparticles of 100a1000 nm in diameter. The self-assemblies may be loaded with drugs or may present as micelle forming polymeradrug conjugates and the supramolecular aggregates have been employed as drug solubilisers, tumour targeting agents, gene delivery vectors and facilitators of intracellular drug uptake, with a more promising polymeradrug conjugate progressing to clinical testing. The formulation of drug compounds into medicines will increasingly rely on the use of specially tailored molecules, which fundamentally alter the drug's pharmacokinetics to enable its therapeutic activity. This is particularly true of the more challenging hydrophobic drugs or therapeutic biological molecules. The demand for such enabled medicines will translate into a demand for advanced highly functionalised drug delivery materials. Polymers have been used to formulate medicines for many decades and this is unlikely to change soon. Amphiphilic polymers based on amino acids are the subject of this review. These molecules, which present as either poly(l-amino acid) block copolymers or poly(l‐amino acid) backbones with hydrophobic substituents, self assemble into micelles, vesicles, nanofibres and solid nanoparticles and such self assemblies, have drug delivery capabilities. The nature of the self-assembly depends on the chemistry of the constituent molecules, with the more hydrophilic molecules forming nanosized micellar aggregates including peptide nanofibres, molecules of intermediate hydrophobicity forming polymeric vesicles and the more hydrophobic variants forming amorphous polymeric nanoparticles of 100–1000nm in diameter. The self-assemblies may be loaded with drugs or may present as micelle forming polymer–drug conjugates and the supramolecular aggregates have been employed as drug solubilisers, tumour targeting agents, gene delivery vectors and facilitators of intracellular drug uptake, with a more promising polymer–drug conjugate progressing to clinical testing. The formulation of drug compounds into medicines will increasingly rely on the use of specially tailored molecules, which fundamentally alter the drug's pharmacokinetics to enable its therapeutic activity. This is particularly true of the more challenging hydrophobic drugs or therapeutic biological molecules. The demand for such enabled medicines will translate into a demand for advanced highly functionalised drug delivery materials. Polymers have been used to formulate medicines for many decades and this is unlikely to change soon. Amphiphilic polymers based on amino acids are the subject of this review. These molecules, which present as either poly(l-amino acid) block copolymers or poly(l‐amino acid) backbones with hydrophobic substituents, self assemble into micelles, vesicles, nanofibres and solid nanoparticles and such self assemblies, have drug delivery capabilities. The nature of the self-assembly depends on the chemistry of the constituent molecules, with the more hydrophilic molecules forming nanosized micellar aggregates including peptide nanofibres, molecules of intermediate hydrophobicity forming polymeric vesicles and the more hydrophobic variants forming amorphous polymeric nanoparticles of 100–1000nm in diameter. The self-assemblies may be loaded with drugs or may present as micelle forming polymer–drug conjugates and the supramolecular aggregates have been employed as drug solubilisers, tumour targeting agents, gene delivery vectors and facilitators of intracellular drug uptake, with a more promising polymer–drug conjugate progressing to clinical testing. [Display omitted] The formulation of drug compounds into medicines will increasingly rely on the use of specially tailored molecules, which fundamentally alter the drug's pharmacokinetics to enable its therapeutic activity. This is particularly true of the more challenging hydrophobic drugs or therapeutic biological molecules. The demand for such enabled medicines will translate into a demand for advanced highly functionalised drug delivery materials. Polymers have been used to formulate medicines for many decades and this is unlikely to change soon. Amphiphilic polymers based on amino acids are the subject of this review. These molecules, which present as either poly(L-amino acid) block copolymers or poly(L-amino acid) backbones with hydrophobic substituents, self assemble into micelles, vesicles, nanofibres and solid nanoparticles and such self assemblies, have drug delivery capabilities. The nature of the self-assembly depends on the chemistry of the constituent molecules, with the more hydrophilic molecules forming nanosized micellar aggregates including peptide nanofibres, molecules of intermediate hydrophobicity forming polymeric vesicles and the more hydrophobic variants forming amorphous polymeric nanoparticles of 100-1000 nm in diameter. The self-assemblies may be loaded with drugs or may present as micelle forming polymer-drug conjugates and the supramolecular aggregates have been employed as drug solubilisers, tumour targeting agents, gene delivery vectors and facilitators of intracellular drug uptake, with a more promising polymer-drug conjugate progressing to clinical testing.The formulation of drug compounds into medicines will increasingly rely on the use of specially tailored molecules, which fundamentally alter the drug's pharmacokinetics to enable its therapeutic activity. This is particularly true of the more challenging hydrophobic drugs or therapeutic biological molecules. The demand for such enabled medicines will translate into a demand for advanced highly functionalised drug delivery materials. Polymers have been used to formulate medicines for many decades and this is unlikely to change soon. Amphiphilic polymers based on amino acids are the subject of this review. These molecules, which present as either poly(L-amino acid) block copolymers or poly(L-amino acid) backbones with hydrophobic substituents, self assemble into micelles, vesicles, nanofibres and solid nanoparticles and such self assemblies, have drug delivery capabilities. The nature of the self-assembly depends on the chemistry of the constituent molecules, with the more hydrophilic molecules forming nanosized micellar aggregates including peptide nanofibres, molecules of intermediate hydrophobicity forming polymeric vesicles and the more hydrophobic variants forming amorphous polymeric nanoparticles of 100-1000 nm in diameter. The self-assemblies may be loaded with drugs or may present as micelle forming polymer-drug conjugates and the supramolecular aggregates have been employed as drug solubilisers, tumour targeting agents, gene delivery vectors and facilitators of intracellular drug uptake, with a more promising polymer-drug conjugate progressing to clinical testing. The formulation of drug compounds into medicines will increasingly rely on the use of specially tailored molecules, which fundamentally alter the drug's pharmacokinetics to enable its therapeutic activity. This is particularly true of the more challenging hydrophobic drugs or therapeutic biological molecules. The demand for such enabled medicines will translate into a demand for advanced highly functionalised drug delivery materials. Polymers have been used to formulate medicines for many decades and this is unlikely to change soon. Amphiphilic polymers based on amino acids are the subject of this review. These molecules, which present as either poly(L-amino acid) block copolymers or poly(L-amino acid) backbones with hydrophobic substituents, self assemble into micelles, vesicles, nanofibres and solid nanoparticles and such self assemblies, have drug delivery capabilities. The nature of the self-assembly depends on the chemistry of the constituent molecules, with the more hydrophilic molecules forming nanosized micellar aggregates including peptide nanofibres, molecules of intermediate hydrophobicity forming polymeric vesicles and the more hydrophobic variants forming amorphous polymeric nanoparticles of 100-1000 nm in diameter. The self-assemblies may be loaded with drugs or may present as micelle forming polymer-drug conjugates and the supramolecular aggregates have been employed as drug solubilisers, tumour targeting agents, gene delivery vectors and facilitators of intracellular drug uptake, with a more promising polymer-drug conjugate progressing to clinical testing. |
| Author | Lalatsa, Aikaterini Mazza, Mariarosa Le, Thi Bich Hang Schätzlein, Andreas G. Uchegbu, Ijeoma F. |
| Author_xml | – sequence: 1 givenname: Aikaterini surname: Lalatsa fullname: Lalatsa, Aikaterini – sequence: 2 givenname: Andreas G. surname: Schätzlein fullname: Schätzlein, Andreas G. – sequence: 3 givenname: Mariarosa surname: Mazza fullname: Mazza, Mariarosa – sequence: 4 givenname: Thi Bich Hang surname: Le fullname: Le, Thi Bich Hang – sequence: 5 givenname: Ijeoma F. surname: Uchegbu fullname: Uchegbu, Ijeoma F. email: Ijeoma.uchegbu@ucl.ac.uk |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22613882$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkc1uEzEUhS1URNPCIwCzLIsJ_v8Ri6qKKCBVsICuLcdzXRzNjIM9KcqOh-AJeZI6JN2wCdKRLOt-517de87QyZhGQOglwXOCiXy7mq98GjP0c4oJnWNeJZ-gGdGKtdwYcYJmldMtk8KcorNSVhhjwbh6hk4plYRpTWdocTWsv8eqPvpmnfrtRd-6IY6pcT525U3z59fv5jP8bAY3QY6uL01Iueny5q7poI_3kLfP0dNQC_Di8J6j2-v33xYf25svHz4trm5aLyiZWqG4V4YpIBzLbmmM50EEhQ3DJnDBmNRaG8qJdlQsMV6aEFj9e8Y70Iqyc3Sx77vO6ccGymSHWDz0vRshbYqt20pFFGbiOIoZ11Rzqv4DpYT8vVdFXx3QzXKAzq5zHFze2sdzVuDdHvA5lZIhWB8nN8U0TtnFvvayu_Dsyh7Cs7vwLOZVsrrFP-7HAcd8r_e-4JJ1dzkWe_u1AgJjoqRSux0v9wTUeO4jZFt8hNFDFzP4yXYpHpnxAN7UvPU |
| CitedBy_id | crossref_primary_10_1016_j_colsurfb_2019_03_055 crossref_primary_10_1016_j_biomaterials_2013_07_037 crossref_primary_10_1049_mnl_2018_5094 crossref_primary_10_1002_marc_202100453 crossref_primary_10_1080_09205063_2017_1374032 crossref_primary_10_1007_s12013_024_01532_1 crossref_primary_10_1016_j_eurpolymj_2023_112469 crossref_primary_10_1007_s11095_020_02915_8 crossref_primary_10_1007_s11426_014_5076_0 crossref_primary_10_3390_gels1020194 crossref_primary_10_1002_pol_20210345 crossref_primary_10_1016_j_jconrel_2014_12_012 crossref_primary_10_1021_cr500542t crossref_primary_10_1021_acsbiomaterials_1c00448 crossref_primary_10_1016_j_jconrel_2021_02_016 crossref_primary_10_1002_pi_4549 crossref_primary_10_1039_C7CC01440F crossref_primary_10_1080_00268976_2017_1347295 crossref_primary_10_1016_j_eurpolymj_2016_10_029 crossref_primary_10_1371_journal_pone_0097358 crossref_primary_10_1016_j_biomaterials_2013_10_063 crossref_primary_10_1016_j_colsurfb_2016_06_038 crossref_primary_10_1021_bm501065q crossref_primary_10_1021_acs_molpharmaceut_8b01074 crossref_primary_10_1136_bjophthalmol_2015_308250 crossref_primary_10_1039_C6RA04335F crossref_primary_10_1002_jbm_a_35931 crossref_primary_10_1021_acs_joc_5b00396 crossref_primary_10_1021_am303073u crossref_primary_10_3390_ma10020170 crossref_primary_10_1021_bm500169p crossref_primary_10_1021_la304909r crossref_primary_10_1039_C2TB00063F crossref_primary_10_1002_macp_202300207 crossref_primary_10_1021_acs_biomac_9b01124 crossref_primary_10_1002_mats_202200070 crossref_primary_10_1021_acs_langmuir_5b01949 crossref_primary_10_1016_j_eurpolymj_2014_09_001 crossref_primary_10_1021_acs_langmuir_3c01973 crossref_primary_10_1002_smll_201301885 crossref_primary_10_1002_pola_28938 crossref_primary_10_1016_j_jconrel_2014_10_028 crossref_primary_10_4155_tde_2016_0051 crossref_primary_10_1039_C4PY00628C crossref_primary_10_1039_C9RA09189K crossref_primary_10_1002_pi_5618 crossref_primary_10_1071_CH14350 crossref_primary_10_1016_j_eurpolymj_2024_113424 crossref_primary_10_1007_s10965_017_1277_5 crossref_primary_10_1038_s41586_021_03399_1 crossref_primary_10_1016_j_colsurfb_2018_07_007 crossref_primary_10_1007_s12668_020_00744_y crossref_primary_10_1016_j_colsurfb_2015_07_026 crossref_primary_10_1016_j_fuel_2024_131237 crossref_primary_10_1021_acs_chemrev_5b00346 crossref_primary_10_1039_c3tb20431f crossref_primary_10_1049_iet_nbt_2017_0219 crossref_primary_10_1517_17425247_2014_935337 crossref_primary_10_1021_bm500296n crossref_primary_10_1039_C7NR09612G crossref_primary_10_1002_slct_202401655 crossref_primary_10_1002_tcr_202200247 crossref_primary_10_1002_pola_27341 crossref_primary_10_1002_pola_27584 crossref_primary_10_1134_S0003683819050065 crossref_primary_10_1021_am5091462 crossref_primary_10_1021_am503179a crossref_primary_10_1177_0883911515585183 crossref_primary_10_1016_j_jconrel_2017_05_025 crossref_primary_10_1080_02652048_2016_1228708 crossref_primary_10_15407_microbiolj79_05_105 crossref_primary_10_1016_j_biomaterials_2013_07_102 crossref_primary_10_1002_adhm_202102329 crossref_primary_10_1021_ma4007939 crossref_primary_10_1007_s00214_023_03087_5 crossref_primary_10_1039_D0PY00135J crossref_primary_10_1039_C5NR02672E crossref_primary_10_1016_j_biotechadv_2013_10_002 crossref_primary_10_1039_D2MA00498D crossref_primary_10_1002_psc_3609 crossref_primary_10_1016_j_ijbiomac_2021_08_036 crossref_primary_10_1016_j_ijpharm_2016_12_007 crossref_primary_10_1039_C7CS00460E crossref_primary_10_3390_polym7111521 crossref_primary_10_1016_j_pnsc_2013_02_009 crossref_primary_10_1038_srep14614 crossref_primary_10_1016_j_ejps_2013_09_016 crossref_primary_10_1016_j_biomaterials_2021_120913 crossref_primary_10_1016_j_seppur_2021_119575 crossref_primary_10_1039_C7OB00931C crossref_primary_10_1002_pola_26794 crossref_primary_10_1016_j_mencom_2020_01_008 crossref_primary_10_1002_pola_28216 crossref_primary_10_1021_acs_nanolett_4c01767 crossref_primary_10_1088_0957_4484_27_40_402002 crossref_primary_10_1039_C3RA44324H crossref_primary_10_1021_nn406285x crossref_primary_10_1021_acsmacrolett_7b00603 crossref_primary_10_1021_acs_biomac_7b01409 crossref_primary_10_1039_C6SC05187A crossref_primary_10_1246_bcsj_20180293 crossref_primary_10_1021_acs_orglett_5b02132 crossref_primary_10_1039_C4SM02656J crossref_primary_10_3390_pharmaceutics10010032 crossref_primary_10_1021_acsanm_1c00693 crossref_primary_10_1007_s13726_017_0559_4 crossref_primary_10_1039_C4RA12255K crossref_primary_10_1039_c3dt32830a crossref_primary_10_1039_C7BM00730B crossref_primary_10_1002_mabi_201300222 crossref_primary_10_1080_08927022_2015_1079907 crossref_primary_10_1002_pi_4710 crossref_primary_10_1016_j_foodchem_2025_142751 crossref_primary_10_1021_ja5125308 crossref_primary_10_1016_j_addr_2016_08_003 |
| Cites_doi | 10.1073/pnas.072699999 10.1016/j.biomaterials.2009.01.056 10.1016/S0168-3659(01)00341-8 10.1126/science.1063187 10.3109/02841869409083948 10.1016/j.biomaterials.2009.07.063 10.1163/156856202760319144 10.1021/js970304s 10.1021/jp0018899 10.1021/bc950089b 10.1021/bc025555t 10.1021/la701038f 10.1038/sj.bjc.6603311 10.1016/S0168-3659(99)00133-9 10.1038/sj.bjc.6602204 10.1038/nmat1093 10.1038/nnano.2009.153 10.1002/1097-4636(20001215)52:4<831::AID-JBM29>3.0.CO;2-K 10.1517/17425247.3.5.629 10.1016/S0169-409X(02)00015-7 10.1038/sj.bjc.6602479 10.1021/ja0381050 10.1158/0008-5472.CAN-09-3267 10.1016/S0168-3659(99)00248-5 10.1016/S0927-7765(03)00125-5 10.1158/1078-0432.CCR-06-2821 10.1007/s10637-011-9709-2 10.1111/j.1365-2796.2009.02184.x 10.1021/bc000052d 10.1016/j.actbio.2009.07.031 10.1038/nnano.2006.139 10.1016/S0168-3659(01)00537-5 10.1021/ja9627656 10.1016/j.biomaterials.2009.03.006 10.1016/S0168-3659(97)00245-9 10.1021/bc0341573 10.1038/bjc.2011.6 10.1021/js950204r 10.1021/mp200469a 10.1016/S0378-5173(01)00861-4 10.1016/S0168-3659(01)00314-5 10.1023/A:1010908916184 10.1073/pnas.191250198 10.1021/la026526+ 10.1016/j.ejpb.2011.02.007 10.1023/A:1007529218802 10.1039/b609047h 10.1023/A:1016266523505 10.1016/j.jconrel.2003.08.022 10.1016/0169-409X(95)00031-2 10.1021/la9027282 10.1016/S1359-0294(03)00081-5 10.1002/anie.200500519 10.1021/bm0604000 10.1021/bm060130l 10.1098/rsif.2010.0190.focus 10.1016/S0168-3659(97)00163-6 10.1021/bi801072s 10.1038/sj.bjc.6603855 10.1021/la0115583 10.1016/0168-3659(94)90118-X 10.1038/nrd1088 10.1098/rsta.2007.2024 10.1002/bip.21328 10.1007/0-306-47932-X_6 10.1021/la980104b 10.1016/S1367-5931(02)00391-5 10.1039/c0sm00321b 10.1021/ar8000926 10.1021/mp300009u 10.1111/j.1349-7006.2009.01103.x 10.1073/pnas.90.8.3334 10.1016/S0378-5173(99)00202-1 10.1038/sj.bjc.6602772 10.1016/S0168-3659(98)00095-9 10.1016/S1359-6349(10)70002-1 10.1021/ma049042o 10.1016/j.actbio.2005.04.002 10.1021/ma971277v 10.1021/la052756n 10.1021/la980572l 10.1021/ja060573x 10.1016/S0168-3659(03)00205-0 10.1039/b310574a 10.1016/S0168-3659(98)00054-6 10.1016/S0168-3659(02)00347-4 10.1016/S0142-9612(03)00347-8 10.1615/CritRevTherDrugCarrierSyst.v20.i5.20 10.1021/la000633r 10.1021/la0625345 10.3109/10611869909085500 10.1523/JNEUROSCI.0143-08.2008 10.1021/la8007848 10.1042/BST0350535 10.1016/j.jconrel.2005.08.003 10.1021/bm0257614 10.1038/417424a 10.1006/jcis.2001.7463 10.1126/science.1082387 10.1002/jps.10397 10.1021/la001078w 10.1016/S0168-3659(97)00115-6 10.1016/S0168-3659(01)00477-1 10.1021/ja110966y 10.2174/157489209789206869 10.1126/science.2781283 |
| ContentType | Journal Article |
| Copyright | 2012 Crown Copyright © 2012. Published by Elsevier B.V. All rights reserved. |
| Copyright_xml | – notice: 2012 – notice: Crown Copyright © 2012. Published by Elsevier B.V. All rights reserved. |
| DBID | FBQ AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 7QO 8FD FR3 P64 7S9 L.6 |
| DOI | 10.1016/j.jconrel.2012.04.046 |
| DatabaseName | AGRIS CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic Biotechnology Research Abstracts Technology Research Database Engineering Research Database Biotechnology and BioEngineering Abstracts AGRICOLA AGRICOLA - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic Engineering Research Database Biotechnology Research Abstracts Technology Research Database Biotechnology and BioEngineering Abstracts AGRICOLA AGRICOLA - Academic |
| DatabaseTitleList | Engineering Research Database MEDLINE - Academic MEDLINE AGRICOLA |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: FBQ name: AGRIS url: http://www.fao.org/agris/Centre.asp?Menu_1ID=DB&Menu_2ID=DB1&Language=EN&Content=http://www.fao.org/agris/search?Language=EN sourceTypes: Publisher |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Pharmacy, Therapeutics, & Pharmacology |
| EISSN | 1873-4995 |
| EndPage | 536 |
| ExternalDocumentID | 22613882 10_1016_j_jconrel_2012_04_046 US201500176777 S0168365912004063 |
| Genre | Journal Article Review |
| GroupedDBID | --- --K --M .~1 0R~ 1B1 1RT 1~. 1~5 4.4 457 4G. 53G 5GY 5VS 7-5 71M 8P~ 9JM AABNK AABXZ AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AATCM AAXUO ABFNM ABFRF ABJNI ABMAC ABOCM ABXDB ABYKQ ABZDS ACDAQ ACGFO ACGFS ACIUM ACNNM ACRLP ADBBV ADEZE ADMUD AEBSH AEFWE AEKER AENEX AEZYN AFKWA AFRZQ AFTJW AFXIZ AGHFR AGUBO AGYEJ AIEXJ AIKHN AITUG AJBFU AJOXV ALCLG ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ AXJTR BKOJK BLXMC C45 CS3 DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FIRID FNPLU FYGXN G-Q GBLVA HMT HZ~ IHE J1W KOM M34 M41 MO0 N9A O-L O9- OAUVE OGGZJ OVD OZT P-8 P-9 P2P PC. Q38 RIG RNS ROL RPZ SCC SDF SDG SDP SES SPC SPCBC SSM SSP SSZ T5K TEORI ~G- .GJ 29K 3O- AAQXK AAYOK ABPIF ABPTK AHHHB ASPBG AVWKF AZFZN D-I FBQ FEDTE FGOYB G-2 HVGLF R2- SEW SPT WUQ AAHBH AATTM AAXKI AAYWO AAYXX ABWVN ACRPL ACVFH ADCNI ADNMO AEIPS AEUPX AFJKZ AFPUW AGCQF AGQPQ AGRNS AIGII AIIUN AKBMS AKRWK AKYEP ANKPU APXCP BNPGV CITATION SSH CGR CUY CVF ECM EIF NPM 7X8 7QO 8FD FR3 P64 7S9 L.6 |
| ID | FETCH-LOGICAL-c521t-574c7937e1406db99c4f5f709309f4533688892418a25b00b9ff3924c34de8723 |
| IEDL.DBID | .~1 |
| ISSN | 0168-3659 1873-4995 |
| IngestDate | Fri Jul 11 05:26:43 EDT 2025 Fri Jul 11 09:19:45 EDT 2025 Fri Jul 11 09:58:53 EDT 2025 Thu Apr 03 07:04:45 EDT 2025 Tue Jul 01 04:04:12 EDT 2025 Thu Apr 24 22:59:12 EDT 2025 Wed Dec 27 19:15:47 EST 2023 Fri Feb 23 02:28:57 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 2 |
| Keywords | Solid polymeric nanoparticles Self-assembly Peptide amphiphiles Polymeric vesicles Polymeric micelles |
| Language | English |
| License | https://www.elsevier.com/tdm/userlicense/1.0 Crown Copyright © 2012. Published by Elsevier B.V. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c521t-574c7937e1406db99c4f5f709309f4533688892418a25b00b9ff3924c34de8723 |
| Notes | http://dx.doi.org/10.1016/j.jconrel.2012.04.046 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 ObjectType-Article-2 ObjectType-Feature-1 |
| PMID | 22613882 |
| PQID | 1021126138 |
| PQPubID | 23479 |
| PageCount | 14 |
| ParticipantIDs | proquest_miscellaneous_1686717035 proquest_miscellaneous_1034828427 proquest_miscellaneous_1021126138 pubmed_primary_22613882 crossref_citationtrail_10_1016_j_jconrel_2012_04_046 crossref_primary_10_1016_j_jconrel_2012_04_046 fao_agris_US201500176777 elsevier_sciencedirect_doi_10_1016_j_jconrel_2012_04_046 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2012-07-20 |
| PublicationDateYYYYMMDD | 2012-07-20 |
| PublicationDate_xml | – month: 07 year: 2012 text: 2012-07-20 day: 20 |
| PublicationDecade | 2010 |
| PublicationPlace | Netherlands |
| PublicationPlace_xml | – name: Netherlands |
| PublicationTitle | Journal of controlled release |
| PublicationTitleAlternate | J Control Release |
| PublicationYear | 2012 |
| Publisher | Elsevier B.V |
| Publisher_xml | – name: Elsevier B.V |
| References | Yokoyama, Satoh, Sakurai, Okano, Matsumura, Kakizoe, Kataoka (bb0275) 1998; 55 Beniash, Hartgerink, Storrie, Stendahl, Stupp (bb0485) 2005; 1 Jeong, Nah, Lee, Kim, Cho (bb0365) 1999; 188 Lehto, Kortejarvi, Liimatainen, Ojala, Kangas, Hirvonen, Tanninen, Peltonen (bb0195) 2011; 78 Adams, Kwon (bb0090) 2002; 13 Brown, Gray, Tetley, Santovena, Rene, Schätzlein, Uchegbu (bb0105) 2003; 93 Ahmad, Johnston, Mackay, Schätzlein, Gellert, Sengupta, Uchegbu (bb0230) 2010; 7 Matsumura, Hamaguchi, Ura, Muro, Yamada, Shimada, Shirao, Okusaka, Ueno, Ikeda, Watanabe (bb0285) 2004; 91 Yokoyama, Okano, Sakurai, Fukushima, Okamoto, Kataoka (bb0360) 1999; 7 Palmer, Stupp (bb0450) 2008; 41 Koehler, Raghavan, Kaler (bb0145) 2000; 104 Fu, Sun, Zhang, Sui, Yan, He (bb0025) 2009; 4 Lee, Stupp, Schatz (bb0100) 2011; 133 Cheng, Gray, Tetley, Hang, Schätzlein, Uchegbu (bb0175) 2006; 7 Nishiyama, Kato, Sugiyama, Kataoka (bb0385) 2001; 18 Van Domeselaar, Kwon, Andrew, Wishart (bb0125) 2003; 30 Cortes, Saura (bb0020) 2010; 8 Nishiyama, Yokoyama, Aoyagi, Okano, Sakurai, Kataoka (bb0250) 1999; 15 Lalatsa, Lee, Zloh, Schatzlein, Uchegbu (bb0620) 2012 Bogdanov, Martin, Bogdanova, Brady, Weissleder (bb0380) 1996; 7 Tanford (bb0070) 1980 Negishi, Koizumi, Uchino, Kuroda, Kawaguchi, Naito, Matsumura (bb0355) 2006; 95 von Maltzahn, Vauthey, Santoso, Zhang (bb0525) 2003; 19 Webber, Kessler, Stupp (bb0490) 2010; 267 Mazza, Gaisford, McCarthy, Schätzlein, Uchegbu (bb0605) 2011 Yu, Okano, Kataoka, Sardari, Kwon (bb0310) 1998; 56 Chu-Kung, Bozzelli, Lockwood, Haseman, Mayo, Tirrell (bb0540) 2004; 15 Xing, Mattice (bb0225) 1998; 14 Homsi, Simon, Garrett, Springett, De Conti, Chiappori, Munster, Burton, Stromatt, Allievi, Angiuli, Eisenfeld, Sullivan, Daud (bb0415) 2007; 13 Hartgerink, Beniash, Stupp (bb0440) 2001; 294 Gribbon, Channon, Zhang, Banwell, Bromley, Chaudhuri, Oreffo, Woolfson (bb0515) 2008; 47 Yokoyama, Fukushima, Uehara, Okamoto, Kataoka, Sakurai, Okano (bb0240) 1998; 50 Hartgerink, Beniash, Stupp (bb0445) 2002; 99 Adams, Andes, Kwon (bb0205) 2003; 4 Harada, Kataoka (bb0610) 1998; 31 Zhang, Marini, Hwang, Santoso (bb0425) 2002; 6 Yu, Tirrell, Fields (bb0510) 1998; 118 Kwon, Kataoka (bb0320) 1995; 16 Wang, Tetley, Uchegbu (bb0050) 2001; 237 Brown, Schätzlein, Brownlie, Jack, Wang, Tetley, Gray, Uchegbu (bb0055) 2000; 11 Hamaguchi, Kato, Yasui, Morizane, Ikeda, Ueno, Muro, Yamada, Okusaka, Shirao, Shimada, Nakahama, Matsumura (bb0405) 2007; 97 Duncan (bb0265) 2003; 2 Yang, Gu, Zhang, Wang, Xu (bb0625) 2004 Uchegbu, Anderson, Brownlie (bb0005) 2006 Liu, Xu, Wang, Tan, Fan, Venkatraman, Li, Yang (bb0435) 2009; 4 Webber, Kessler, Stupp (bb0460) 2009; 267 Lavasanifar, Samuel, Kwon (bb0340) 2000; 52 Palmer, Velichko, de la Cruz, Stupp (bb0455) 2007; 365 Cui, Webber, Stupp (bb0065) 2010; 94 Plummer, Wilson, Calvert, Boddy, Griffin, Sludden, Tilby, Eatock, Pearson, Ottley, Matsumura, Kataoka, Nishiya (bb0375) 2011; 104 Kwon, Naito, Yokoyama, Okano, Sakurai, Kataoka (bb0325) 1995; 12 Wiradharma, Tong, Yang (bb0535) 2009; 30 Uchegbu, Schätzlein (bb0010) 2006 Nishiyama, Kataoka (bb0390) 2001; 74 Gregoriadis (bb0590) 2006; volumes I, II and III Zhang, Holmes, Lockshin, Rich (bb0430) 1993; 90 Brown, Schätzlein, Uchegbu (bb0040) 2001; 229 Nowak, Breedveld, Pakstis, Ozbas, Pine, Pochan, Deming (bb0560) 2002; 417 Lavasanifar, Samuel, Kwon (bb0345) 2001; 77 Ulijn, Smith (bb0420) 2008; 37 Ghanaati, Webber, Unger, Orth, Hulvat, Kiehna, Barbeck, Rasic, Stupp, Kirkpatrick (bb0575) 2009; 30 Wang, Qu, Gray, Tetley, Uchegbu (bb0120) 2004; 37 Itaka, Yamauchi, Harada, Nakamura, Kawaguchi, Kataoka (bb0130) 2003; 24 Jayawarna, Smith, Gough, Ulijn (bb0495) 2007; 35 Aggeli, Nyrkova, Bell, Harding, Carrick, McLeish, Semenov, Boden (bb0505) 2001; 98 Katayose, Kataoka (bb0400) 1998; 87 Hamaguchi, Matsumura, Suzuki, Shimizu, Goda, Nakamura, Nakatomi, Yokoyama, Kataoka, Kakizoe (bb0350) 2005; 92 Singer, Baker, De Vries, Kumar, Shaffer, Vawter, Bolton, Garzone (bb0410) 2003; 519 Kwon (bb0315) 2003; 20 Lee, Shin, Na, Bae (bb0165) 2003; 90 Matsumura, Kataoka (bb0290) 2009; 100 Kato, Chin, Yoshikawa, Yamaguchi, Tsuji, Esaki, Sakai, Kimura, Hamaguchi, Shimada, Matsumura, Ikeda (bb0615) 2011 Kaler, Murthy, Rodriguez, Zasadzinski (bb0155) 1989; 245 Bellomo, Wyrsta, Pakstis, Pochan, Deming (bb0305) 2004; 3 La, Okano, Kataoka (bb0330) 1996; 85 Nishiyama, Koizumi, Okazaki, Matsumura, Nishio, Kataoka (bb0395) 2003; 14 Yang, Song, Ao, Nowak, Abelowitz, Korsak, Havton, Deming, Sofroniew (bb0570) 2009; 30 Yokoyama, Miyauchi, Yamada, Okano, Sakurai, Kataoka, Inoue (bb0115) 1990; 50 Gabizon, Isacson, Libson, Kaufman, Uziely, Catane, Bendor, Rabello, Cass, Peretz, Sulkes, Chisin, Barenholz (bb0030) 1994; 33 Adams, Lavasanifar, Kwon (bb0335) 2003; 92 Lavasanifar, Samuel, Kwon (bb0220) 2002; 79 Maeda, Wu, Sawa, Matsumura, Hori (bb0245) 2000; 65 Akagi, Kaneko, Kida, Akashi (bb0060) 2005; 108 Raghavan, Fritz, Kaler (bb0600) 2002; 18 Jeong, Cheon, Kim, Nah, Lee, Sung, Akaike, Cho (bb0370) 1998; 51 Li, Kunieda (bb0150) 2003; 8 Nishiyama, Okazaki, Cabral, Miyamoto, Kato, Sugiyama, Nishio, Matsumura, Kataoka (bb0255) 2003; 63 Lavasanifar, Samuel, Kwon (bb0045) 2002; 54 Florence, Attwood (bb0595) 2006 Reches, Gazit (bb0475) 2003; 300 Paramonov, Jun, Hartgerink (bb0465) 2006; 128 Reches, Gazit (bb0480) 2006; 1 Mardilovich, Craig, McCammon, Garg, Kokkoli (bb0550) 2006; 22 Tysseling-Mattiace, Sahni, Niece, Birch, Czeisler, Fehlings, Stupp, Kessler (bb0580) 2008; 28 Wang, Tetley, Uchegbu (bb0095) 2000; 16 Israelachvili (bb0135) 1991 Uchegbu (bb0585) 2006; 3 Keller, Sauer, Strauss, Gast, Dathe, Bienert (bb0530) 2005; 44 Veronese (bb0035) 2009 Wang, McConaghy, Tetley, Uchegbu (bb0200) 2001; 17 Kataoka, Matsumoto, Yokoyama, Okano, Sakurai, Fukushima, Okamoto, Kwon (bb0185) 2000; 64 Webber, Tongers, Renault, Roncalli, Losordo, Stupp (bb0545) 2010; 6 Standley, Toft, Cheng, Soukasene, Chen, Raja, Band, Band, Cryns, Stupp (bb0110) 2010; 70 Kwon, Suwa, Yokoyama, Okano, Sakuraia, Kataoka (bb0210) 1994; 29 Meijer, Roeters, Viola, Lowik, Vriend, van Hest (bb0520) 2007; 23 Sun, Chen, Deng, Yu, Xie, Jing (bb0300) 2007; 23 Uchino, Matsumura, Negishi, Koizumi, Hayashi, Honda, Nishiyama, Kataoka, Naito, Kakizoe (bb0260) 2005; 93 Chooi, Gray, Tetley, Fan, Uchegbu (bb0080) 2010; 26 Li, Kwon (bb0270) 2000; 17 Qu, Omar, Le, Tetley, Bolton, Chooi, Wang, Uchegbu (bb0180) 2008; 24 Nowak, Breedveld, Pine, Deming (bb0565) 2003; 125 Qu, Khutoryanskiy, Stewart, Rahman, Papahadjopoulos-Sternberg, Dufes, McCarthy, Wilson, Lyons, Carter, Schätzlein, Uchegbu (bb0170) 2006; 7 Yu, Okano, Kataoka, Kwon (bb0235) 1998; 53 Adams, Kwon (bb0215) 2003; 87 Shroff, Rexeisen, Arunagirinathan, Kokkoli (bb0555) 2010; 6 Siew, Le, Thiovolet, Gellert, Schätzlein, Uchegbu (bb0085) 2012; 9 Nakanishi, Fukushima, Okamoto, Suzuki, Matsumura, Yokoyama, Okano, Sakurai, Kataoka (bb0280) 2001; 74 Brown (10.1016/j.jconrel.2012.04.046_bb0105) 2003; 93 Beniash (10.1016/j.jconrel.2012.04.046_bb0485) 2005; 1 Zhang (10.1016/j.jconrel.2012.04.046_bb0425) 2002; 6 Qu (10.1016/j.jconrel.2012.04.046_bb0180) 2008; 24 Meijer (10.1016/j.jconrel.2012.04.046_bb0520) 2007; 23 Homsi (10.1016/j.jconrel.2012.04.046_bb0415) 2007; 13 Keller (10.1016/j.jconrel.2012.04.046_bb0530) 2005; 44 Reches (10.1016/j.jconrel.2012.04.046_bb0475) 2003; 300 Mardilovich (10.1016/j.jconrel.2012.04.046_bb0550) 2006; 22 Veronese (10.1016/j.jconrel.2012.04.046_bb0035) 2009 Hamaguchi (10.1016/j.jconrel.2012.04.046_bb0405) 2007; 97 Ghanaati (10.1016/j.jconrel.2012.04.046_bb0575) 2009; 30 Duncan (10.1016/j.jconrel.2012.04.046_bb0265) 2003; 2 Akagi (10.1016/j.jconrel.2012.04.046_bb0060) 2005; 108 Nishiyama (10.1016/j.jconrel.2012.04.046_bb0395) 2003; 14 Van Domeselaar (10.1016/j.jconrel.2012.04.046_bb0125) 2003; 30 Chu-Kung (10.1016/j.jconrel.2012.04.046_bb0540) 2004; 15 Uchegbu (10.1016/j.jconrel.2012.04.046_bb0585) 2006; 3 Hamaguchi (10.1016/j.jconrel.2012.04.046_bb0350) 2005; 92 Chooi (10.1016/j.jconrel.2012.04.046_bb0080) 2010; 26 Ahmad (10.1016/j.jconrel.2012.04.046_bb0230) 2010; 7 Nishiyama (10.1016/j.jconrel.2012.04.046_bb0250) 1999; 15 Webber (10.1016/j.jconrel.2012.04.046_bb0490) 2010; 267 Wang (10.1016/j.jconrel.2012.04.046_bb0095) 2000; 16 Lavasanifar (10.1016/j.jconrel.2012.04.046_bb0220) 2002; 79 Matsumura (10.1016/j.jconrel.2012.04.046_bb0285) 2004; 91 Plummer (10.1016/j.jconrel.2012.04.046_bb0375) 2011; 104 Yokoyama (10.1016/j.jconrel.2012.04.046_bb0115) 1990; 50 Nishiyama (10.1016/j.jconrel.2012.04.046_bb0255) 2003; 63 Yu (10.1016/j.jconrel.2012.04.046_bb0510) 1998; 118 Adams (10.1016/j.jconrel.2012.04.046_bb0335) 2003; 92 Harada (10.1016/j.jconrel.2012.04.046_bb0610) 1998; 31 Shroff (10.1016/j.jconrel.2012.04.046_bb0555) 2010; 6 Brown (10.1016/j.jconrel.2012.04.046_bb0055) 2000; 11 Katayose (10.1016/j.jconrel.2012.04.046_bb0400) 1998; 87 Sun (10.1016/j.jconrel.2012.04.046_bb0300) 2007; 23 Kwon (10.1016/j.jconrel.2012.04.046_bb0325) 1995; 12 Cortes (10.1016/j.jconrel.2012.04.046_bb0020) 2010; 8 Li (10.1016/j.jconrel.2012.04.046_bb0270) 2000; 17 Adams (10.1016/j.jconrel.2012.04.046_bb0215) 2003; 87 Uchegbu (10.1016/j.jconrel.2012.04.046_bb0010) 2006 Lee (10.1016/j.jconrel.2012.04.046_bb0165) 2003; 90 Maeda (10.1016/j.jconrel.2012.04.046_bb0245) 2000; 65 Raghavan (10.1016/j.jconrel.2012.04.046_bb0600) 2002; 18 Yang (10.1016/j.jconrel.2012.04.046_bb0570) 2009; 30 Fu (10.1016/j.jconrel.2012.04.046_bb0025) 2009; 4 Uchino (10.1016/j.jconrel.2012.04.046_bb0260) 2005; 93 Hartgerink (10.1016/j.jconrel.2012.04.046_bb0445) 2002; 99 Webber (10.1016/j.jconrel.2012.04.046_bb0460) 2009; 267 Koehler (10.1016/j.jconrel.2012.04.046_bb0145) 2000; 104 Lalatsa (10.1016/j.jconrel.2012.04.046_bb0620) 2012 Negishi (10.1016/j.jconrel.2012.04.046_bb0355) 2006; 95 Yang (10.1016/j.jconrel.2012.04.046_bb0625) 2004 Zhang (10.1016/j.jconrel.2012.04.046_bb0430) 1993; 90 Tanford (10.1016/j.jconrel.2012.04.046_bb0070) 1980 Xing (10.1016/j.jconrel.2012.04.046_bb0225) 1998; 14 Palmer (10.1016/j.jconrel.2012.04.046_bb0455) 2007; 365 Kaler (10.1016/j.jconrel.2012.04.046_bb0155) 1989; 245 Nowak (10.1016/j.jconrel.2012.04.046_bb0560) 2002; 417 Yokoyama (10.1016/j.jconrel.2012.04.046_bb0275) 1998; 55 Gribbon (10.1016/j.jconrel.2012.04.046_bb0515) 2008; 47 Bellomo (10.1016/j.jconrel.2012.04.046_bb0305) 2004; 3 Gabizon (10.1016/j.jconrel.2012.04.046_bb0030) 1994; 33 Lavasanifar (10.1016/j.jconrel.2012.04.046_bb0340) 2000; 52 Uchegbu (10.1016/j.jconrel.2012.04.046_bb0005) 2006 Kwon (10.1016/j.jconrel.2012.04.046_bb0320) 1995; 16 Siew (10.1016/j.jconrel.2012.04.046_bb0085) 2012; 9 Mazza (10.1016/j.jconrel.2012.04.046_bb0605) 2011 Singer (10.1016/j.jconrel.2012.04.046_bb0410) 2003; 519 Yu (10.1016/j.jconrel.2012.04.046_bb0310) 1998; 56 Lavasanifar (10.1016/j.jconrel.2012.04.046_bb0345) 2001; 77 Jeong (10.1016/j.jconrel.2012.04.046_bb0365) 1999; 188 Nowak (10.1016/j.jconrel.2012.04.046_bb0565) 2003; 125 Cheng (10.1016/j.jconrel.2012.04.046_bb0175) 2006; 7 Nishiyama (10.1016/j.jconrel.2012.04.046_bb0385) 2001; 18 Matsumura (10.1016/j.jconrel.2012.04.046_bb0290) 2009; 100 Qu (10.1016/j.jconrel.2012.04.046_bb0170) 2006; 7 Gregoriadis (10.1016/j.jconrel.2012.04.046_bb0590) 2006; volumes I, II and III Adams (10.1016/j.jconrel.2012.04.046_bb0090) 2002; 13 Li (10.1016/j.jconrel.2012.04.046_bb0150) 2003; 8 Yokoyama (10.1016/j.jconrel.2012.04.046_bb0360) 1999; 7 Hartgerink (10.1016/j.jconrel.2012.04.046_bb0440) 2001; 294 Bogdanov (10.1016/j.jconrel.2012.04.046_bb0380) 1996; 7 Tysseling-Mattiace (10.1016/j.jconrel.2012.04.046_bb0580) 2008; 28 Florence (10.1016/j.jconrel.2012.04.046_bb0595) 2006 Aggeli (10.1016/j.jconrel.2012.04.046_bb0505) 2001; 98 Paramonov (10.1016/j.jconrel.2012.04.046_bb0465) 2006; 128 Webber (10.1016/j.jconrel.2012.04.046_bb0545) 2010; 6 Yu (10.1016/j.jconrel.2012.04.046_bb0235) 1998; 53 Ulijn (10.1016/j.jconrel.2012.04.046_bb0420) 2008; 37 Itaka (10.1016/j.jconrel.2012.04.046_bb0130) 2003; 24 Lehto (10.1016/j.jconrel.2012.04.046_bb0195) 2011; 78 Nishiyama (10.1016/j.jconrel.2012.04.046_bb0390) 2001; 74 Standley (10.1016/j.jconrel.2012.04.046_bb0110) 2010; 70 Lavasanifar (10.1016/j.jconrel.2012.04.046_bb0045) 2002; 54 Lee (10.1016/j.jconrel.2012.04.046_bb0100) 2011; 133 Brown (10.1016/j.jconrel.2012.04.046_bb0040) 2001; 229 Wiradharma (10.1016/j.jconrel.2012.04.046_bb0535) 2009; 30 Adams (10.1016/j.jconrel.2012.04.046_bb0205) 2003; 4 Wang (10.1016/j.jconrel.2012.04.046_bb0200) 2001; 17 Nakanishi (10.1016/j.jconrel.2012.04.046_bb0280) 2001; 74 Jayawarna (10.1016/j.jconrel.2012.04.046_bb0495) 2007; 35 von Maltzahn (10.1016/j.jconrel.2012.04.046_bb0525) 2003; 19 Kwon (10.1016/j.jconrel.2012.04.046_bb0315) 2003; 20 Palmer (10.1016/j.jconrel.2012.04.046_bb0450) 2008; 41 Cui (10.1016/j.jconrel.2012.04.046_bb0065) 2010; 94 Israelachvili (10.1016/j.jconrel.2012.04.046_bb0135) 1991 Wang (10.1016/j.jconrel.2012.04.046_bb0120) 2004; 37 La (10.1016/j.jconrel.2012.04.046_bb0330) 1996; 85 Yokoyama (10.1016/j.jconrel.2012.04.046_bb0240) 1998; 50 Kataoka (10.1016/j.jconrel.2012.04.046_bb0185) 2000; 64 Wang (10.1016/j.jconrel.2012.04.046_bb0050) 2001; 237 Jeong (10.1016/j.jconrel.2012.04.046_bb0370) 1998; 51 Liu (10.1016/j.jconrel.2012.04.046_bb0435) 2009; 4 Kwon (10.1016/j.jconrel.2012.04.046_bb0210) 1994; 29 Kato (10.1016/j.jconrel.2012.04.046_bb0615) 2011 Reches (10.1016/j.jconrel.2012.04.046_bb0480) 2006; 1 |
| References_xml | – volume: 56 start-page: 285 year: 1998 end-page: 291 ident: bb0310 article-title: In vitro dissociation of antifungal efficacy and toxicity for amphotericin B-loaded poly(ethylene oxide)-block-poly(beta benzyl publication-title: J. Control. Release – volume: 47 start-page: 10365 year: 2008 end-page: 10371 ident: bb0515 article-title: MagicWand: a single, designed peptide that assembles to stable, ordered alpha-helical fibers publication-title: Biochemistry – volume: 16 start-page: 295 year: 1995 ident: bb0320 article-title: Block copolymer micelles as long-circulating drug vehicles publication-title: Adv. Drug Deliv. Rev. – volume: 6 start-page: 5064 year: 2010 ident: bb0555 article-title: Fibronectin-mimetic peptide-amphiphile nanofiber gels support increased cell adhesion and promote ECM production publication-title: Soft Matter – year: 1991 ident: bb0135 article-title: Intermolecular & Surface Forces – volume: 104 start-page: 593 year: 2011 end-page: 598 ident: bb0375 article-title: A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours publication-title: Br. J. Cancer – volume: 95 start-page: 601 year: 2006 end-page: 606 ident: bb0355 article-title: NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel publication-title: Br. J. Cancer – volume: 14 start-page: 4074 year: 1998 end-page: 4080 ident: bb0225 article-title: Large internal structures of micelles of triblock copolymers with small insoluble molecules in their cores publication-title: Langmuir – volume: 9 start-page: 14 year: 2012 end-page: 18 ident: bb0085 article-title: Enhanced oral absorption of hydrophobic and hydrophilic drugs using quaternary ammonium palmitoyl glycol chitosan nanoparticles publication-title: Mol. Pharm. – volume: 19 start-page: 4332 year: 2003 end-page: 4337 ident: bb0525 article-title: Positively charged surfactant-like peptides self-assemble into nanostructures publication-title: Langmuir – volume: 128 start-page: 7291 year: 2006 end-page: 7298 ident: bb0465 article-title: Self-assembly of peptide-amphiphile nanofibers: the roles of hydrogen bonding and amphiphilic packing publication-title: J. Am. Chem. Soc. – volume: 22 start-page: 3259 year: 2006 end-page: 3264 ident: bb0550 article-title: Design of a novel fibronectin-mimetic peptide-amphiphile for functionalized biomaterials publication-title: Langmuir – volume: 365 start-page: 1417 year: 2007 end-page: 1433 ident: bb0455 article-title: Supramolecular self-assembly codes for functional structures publication-title: Philos. Transact. A Math. Phys. Eng. Sci. – volume: 8 start-page: 1 year: 2010 end-page: 10 ident: bb0020 article-title: Nanoparticle albumin-bound (nab (TM))-paclitaxel: improving efficacy and tolerability by targeted drug delivery in metastatic breast cancer publication-title: EJC Suppl. – volume: 87 start-page: 23 year: 2003 end-page: 32 ident: bb0215 article-title: Relative aggregation state and hemolytic activity of amphotericin B encapsulated by poly(ethylene oxide)-block-poly(N-hexyl-L-aspartamide)-acyl conjugate micelles: effects of acyl chain length publication-title: J. Control. Release – volume: 108 start-page: 226 year: 2005 end-page: 236 ident: bb0060 article-title: Preparation and characterization of biodegradable nanoparticles based on poly(gamma-glutamic acid) with publication-title: J. Control. Release – volume: 93 start-page: 193 year: 2003 end-page: 211 ident: bb0105 article-title: In vitro and in vivo gene transfer with poly(amino acid) vesicles publication-title: J. Control. Release – volume: 23 start-page: 2058 year: 2007 end-page: 2063 ident: bb0520 article-title: Stabilization of peptide fibrils by hydrophobic interaction publication-title: Langmuir – volume: 118 start-page: 12515 year: 1998 end-page: 12520 ident: bb0510 article-title: Self-assembling amphiphiles for construction of protein molecular architecture publication-title: J. Am. Chem. Soc. – volume: 18 year: 2002 ident: bb0600 article-title: Wormy micelles formed by synergistic self-assembly in mixtures of anionic and cationic surfactants publication-title: Langmuir – volume: 3 start-page: 629 year: 2006 end-page: 640 ident: bb0585 article-title: Pharmaceutical nanotechnology: polymeric vesicles for drug and gene delivery publication-title: Expert Opin. Drug Deliv. – year: 2009 ident: bb0035 article-title: PEGylated Protein Drugs: Basic Science and Clinical Applications – volume: 6 start-page: 3 year: 2010 end-page: 11 ident: bb0545 article-title: Development of bioactive peptide amphiphiles for therapeutic cell delivery publication-title: Acta Biomater. – volume: 26 start-page: 2301 year: 2010 end-page: 2316 ident: bb0080 article-title: The molecular shape of poly(propylenimine) dendrimers has a profound effect on their self assembly publication-title: Langmuir – volume: 3 start-page: 244 year: 2004 end-page: 248 ident: bb0305 article-title: Stimuli-responsive polypeptide vesicles by conformation‐specific assembly publication-title: Nat. Mater. – year: 2006 ident: bb0595 article-title: Physicochemical Principles of Pharmacy – volume: 90 start-page: 363 year: 2003 end-page: 374 ident: bb0165 article-title: Poly(L-histidine)-PEG block copolymer micelles and pH-induced destabilization publication-title: J. Control. Release – volume: 16 start-page: 7859 year: 2000 end-page: 7866 ident: bb0095 article-title: A new class of amphiphilic poly- publication-title: Langmuir – volume: 51 start-page: 169 year: 1998 end-page: 178 ident: bb0370 article-title: Clonazepam release from core-shell type nanoparticles in vitro publication-title: J. Control. Release – volume: 14 start-page: 449 year: 2003 end-page: 457 ident: bb0395 article-title: Differential gene expression profile between PC-14 cells treated with free cisplatin and cisplatin-incorporated polymeric micelles publication-title: Bioconjug. Chem. – year: 2011 ident: bb0615 article-title: Phase II study of NK105, a paclitaxel-incorporating micellar nanoparticle, for previously treated advanced or recurrent gastric cancer publication-title: Invest. New Drugs – volume: 35 start-page: 535 year: 2007 end-page: 537 ident: bb0495 article-title: Three-dimensional cell culture of chondrocytes on modified di-phenylalanine scaffolds publication-title: Biochem. Soc. Trans. – volume: 94 start-page: 1 year: 2010 end-page: 18 ident: bb0065 article-title: Self-assembly of peptide amphiphiles: from molecules to nanostructures to biomaterials publication-title: Biopolymers – volume: 17 start-page: 631 year: 2001 end-page: 636 ident: bb0200 article-title: Controls on polymer molecular weight may be used to control the size of palmitoyl glycol chitosan polymeric vesicles publication-title: Langmuir – volume: 87 start-page: 160 year: 1998 end-page: 163 ident: bb0400 article-title: Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly( publication-title: J. Pharm. Sci. – volume: 7 start-page: S423 year: 2010 end-page: S433 ident: bb0230 article-title: In silico modelling of drug–polymer interactions for pharmaceutical formulations publication-title: J. R. Soc. Interface – volume: 20 start-page: 357 year: 2003 end-page: 403 ident: bb0315 article-title: Polymeric micelles for delivery of poorly water-soluble compounds publication-title: Crit. Rev. Ther. Drug Carrier Syst. – volume: 63 start-page: 8977 year: 2003 end-page: 8983 ident: bb0255 article-title: Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice publication-title: Cancer Res. – volume: 17 start-page: 607 year: 2000 end-page: 611 ident: bb0270 article-title: Methotrexate esters of poly(ethylene oxide)-block-poly(2-hydroxyethyl-L-aspartamide). Part I: effects of the level of methotrexate conjugation on the stability of micelles and on drug release publication-title: Pharm. Res. – volume: 78 start-page: 531 year: 2011 end-page: 538 ident: bb0195 article-title: Use of conventional surfactant media as surrogates for FaSSIF in simulating in vivo dissolution of BCS class II drugs publication-title: Eur. J. Pharm. Biopharm. – volume: 85 start-page: 85 year: 1996 end-page: 90 ident: bb0330 article-title: Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(beta-benzyl publication-title: J. Pharm. Sci. – volume: 54 start-page: 169 year: 2002 end-page: 190 ident: bb0045 article-title: Poly(ethylene oxide)-block-poly( publication-title: Adv. Drug Deliv. Rev. – volume: 7 start-page: 1509 year: 2006 end-page: 1520 ident: bb0175 article-title: Polyelectrolyte nanoparticles with high drug loading enhance the oral uptake of hydrophobic compounds publication-title: Biomacromolecules – volume: 267 start-page: 71 year: 2010 end-page: 88 ident: bb0490 article-title: Emerging peptide nanomedicine to regenerate tissues and organs publication-title: J. Intern. Med. – volume: 1 start-page: 387 year: 2005 end-page: 397 ident: bb0485 article-title: Self-assembling peptide amphiphile nanofiber matrices for cell entrapment publication-title: Acta Biomater. – volume: 28 start-page: 3814 year: 2008 end-page: 3823 ident: bb0580 article-title: Self-assembling nanofibers inhibit glial scar formation and promote axon elongation after spinal cord injury publication-title: J. Neurosci. – start-page: 131 year: 2006 end-page: 154 ident: bb0005 article-title: Polymeric vesicles publication-title: Polymers in Drug Delivery – volume: 98 start-page: 11857 year: 2001 end-page: 11862 ident: bb0505 article-title: Hierarchical self-assembly of chiral rod-like molecules as a model for peptide beta‐sheet tapes, ribbons, fibrils, and fibers publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 44 start-page: 5252 year: 2005 end-page: 5255 ident: bb0530 article-title: Membrane-mimetic nanocarriers formed by a dipalmitoylated cell-penetrating peptide publication-title: Angew. Chem. Int. Ed Engl. – volume: 11 start-page: 880 year: 2000 end-page: 891 ident: bb0055 article-title: Preliminary characterization of novel amino acid based polymeric vesicles as gene and drug delivery agents publication-title: Bioconjug. Chem. – volume: 133 start-page: 3677 year: 2011 end-page: 3683 ident: bb0100 article-title: Atomistic molecular dynamics simulations of peptide amphiphile self-assembly into cylindrical nanofibers publication-title: J. Am. Chem. Soc. – volume: 294 start-page: 1684 year: 2001 end-page: 1688 ident: bb0440 article-title: Self-assembly and mineralization of peptide-amphiphile nanofibers publication-title: Science – volume: 18 start-page: 1035 year: 2001 end-page: 1041 ident: bb0385 article-title: Cisplatin-loaded polymer–metal complex micelle with time-modulated decaying property as a novel drug delivery system publication-title: Pharm. Res. – volume: 30 start-page: 6202 year: 2009 end-page: 6212 ident: bb0575 article-title: Dynamic in vivo biocompatibility of angiogenic peptide amphiphile nanofibers publication-title: Biomaterials – volume: 519 start-page: 81 year: 2003 end-page: 99 ident: bb0410 article-title: Poly-(L)-glutamic acid–paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: characterization, preclinical pharmacology, and preliminary clinical data publication-title: Adv. Exp. Med. Biol. – start-page: 650 year: 2011 end-page: 653 ident: bb0605 article-title: Fast gelation of self assembling peptide amphiphiles triggered by electromagnetic heating publication-title: Nanotechnology 2011: Advanced Materials, CNTs, Particles, Films and Composites, Chapter 6: Polymer and Soft Nanotechnology, Boston – year: 2012 ident: bb0620 article-title: A Prodrug Nanoparticle Approach for the Oral Delivery of Leucine5-enkephalin to the Brain publication-title: Mol. Pharm. – volume: 13 start-page: 991 year: 2002 end-page: 1006 ident: bb0090 article-title: The effects of acyl chain length on the micelle properties of poly(ethylene oxide)-block-poly(N-hexyl-L-aspartamide)-acyl conjugates publication-title: J. Biomater. Sci. Polym. Ed. – volume: 4 start-page: 457 year: 2009 end-page: 463 ident: bb0435 article-title: Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent publication-title: Nat. Nanotechnol. – volume: 23 start-page: 8308 year: 2007 end-page: 8315 ident: bb0300 article-title: Direct formation of giant vesicles from synthetic polypeptides publication-title: Langmuir – volume: 6 start-page: 865 year: 2002 end-page: 871 ident: bb0425 article-title: Design of nanostructured biological materials through self-assembly of peptides and proteins publication-title: Curr. Opin. Chem. Biol. – year: 2006 ident: bb0010 article-title: Polymers in Drug Delivery – volume: 30 start-page: 323 year: 2003 end-page: 334 ident: bb0125 article-title: Application of solid phase peptide synthesis to engineering PEO-peptide block copolymers for drug delivery publication-title: Colloids Surf. B Biointerfaces – volume: 245 start-page: 1371 year: 1989 end-page: 1374 ident: bb0155 article-title: Spontaneous vesicle formation in aqueous mixtures of single-tailed surfactants publication-title: Science – volume: 31 start-page: 288 year: 1998 end-page: 294 ident: bb0610 article-title: Novel polyion complex micelles entrapping enzyme molecules in the core. Preparation of narrowly-distributed micelles from lysozyme and poly(ethylene glycol)-poly(aspartic acid) block copolymer in aqueous medium publication-title: Macromolecules – volume: 104 start-page: 11035 year: 2000 ident: bb0145 article-title: Microstructure and dynamics of wormlike micelles formed by mixing cationic and anionic surfactants publication-title: J. Phys. Chem. B – volume: 77 start-page: 155 year: 2001 end-page: 160 ident: bb0345 article-title: Micelles self-assembled from poly(ethylene oxide)-block-poly(N-hexyl stearate L-aspartamide) by a solvent evaporation method: effect on the solubilization and haemolytic activity of amphotericin B publication-title: J. Control. Release – volume: 74 start-page: 295 year: 2001 end-page: 302 ident: bb0280 article-title: Development of the polymer micelle carrier system for doxorubicin publication-title: J. Control. Release – volume: 97 start-page: 170 year: 2007 end-page: 176 ident: bb0405 article-title: A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation publication-title: Br. J. Cancer – volume: 92 start-page: 1343 year: 2003 end-page: 1355 ident: bb0335 article-title: Amphiphilic block copolymers for drug delivery publication-title: J. Pharm. Sci. – volume: 24 start-page: 4495 year: 2003 end-page: 4506 ident: bb0130 article-title: Polyion complex micelles from plasmid DNA and poly(ethylene glycol)-poly( publication-title: Biomaterials – volume: 65 start-page: 271 year: 2000 end-page: 284 ident: bb0245 article-title: Tumour vascular permeability and the EPR effect in macromolecular therapeutics: a review publication-title: J. Control. Release – volume: 15 start-page: 377 year: 1999 end-page: 383 ident: bb0250 article-title: Preparation and characterization of self-assembled polymer–metal complex micelle from cis-dichlorodiammineplatinum(II) and poly(ethylene glycol)‐poly(α, β-aspartic acid) block copolymer in an aqueous medium publication-title: Langmuir – volume: 7 start-page: 171 year: 1999 end-page: 186 ident: bb0360 article-title: Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system publication-title: J. Drug Target. – volume: 188 start-page: 49 year: 1999 end-page: 58 ident: bb0365 article-title: Adriamycin release from flower-type polymeric micelle based on star-block copolymer composed of poly(gamma-benzyl publication-title: Int. J. Pharm. – volume: 125 start-page: 15666 year: 2003 end-page: 15670 ident: bb0565 article-title: Unusual salt stability in highly charged diblock co-polypeptide hydrogels publication-title: J. Am. Chem. Soc. – volume: 93 start-page: 678 year: 2005 end-page: 687 ident: bb0260 article-title: Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats publication-title: Br. J. Cancer – volume: volumes I, II and III year: 2006 ident: bb0590 publication-title: Liposome Technology – volume: 15 start-page: 530 year: 2004 end-page: 535 ident: bb0540 article-title: Promotion of peptide antimicrobial activity by fatty acid conjugation publication-title: Bioconjug. Chem. – volume: 29 start-page: 17 year: 1994 end-page: 23 ident: bb0210 article-title: Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer–adriamycin conjugates publication-title: J. Control. Release – volume: 7 start-page: 3452 year: 2006 end-page: 3459 ident: bb0170 article-title: Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude publication-title: Biomacromolecules – volume: 53 start-page: 131 year: 1998 end-page: 136 ident: bb0235 article-title: Polymeric micelles for drug delivery: solubilization and haemolytic activity of amphotericin B publication-title: J. Control. Release – volume: 70 start-page: 3020 year: 2010 end-page: 3026 ident: bb0110 article-title: Induction of cancer cell death by self-assembling nanostructures incorporating a cytotoxic peptide publication-title: Cancer Res. – volume: 7 start-page: 144 year: 1996 end-page: 149 ident: bb0380 article-title: An adduct of cis-diamminedichloroplatinum(II) and poly(ethylene glycol)poly( publication-title: Bioconjug. Chem. – volume: 300 start-page: 625 year: 2003 end-page: 627 ident: bb0475 article-title: Casting metal nanowires within discrete self-assembled peptide nanotubes publication-title: Science – volume: 90 start-page: 3334 year: 1993 end-page: 3338 ident: bb0430 article-title: Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 4 start-page: 750 year: 2003 end-page: 757 ident: bb0205 article-title: Amphotericin B encapsulated in micelles based on poly(ethylene oxide)-block-poly( publication-title: Biomacromolecules – volume: 33 start-page: 779 year: 1994 end-page: 786 ident: bb0030 article-title: Clinical-studies of liposome-encapsulated doxorubicin publication-title: Acta Oncol. – volume: 37 start-page: 9114 year: 2004 end-page: 9122 ident: bb0120 article-title: Self-assembly of cetyl linear polyethylenimine to give micelles, vesicles, and dense nanoparticles publication-title: Macromolecules – volume: 1 start-page: 195 year: 2006 end-page: 200 ident: bb0480 article-title: Controlled patterning of aligned self-assembled peptide nanotubes publication-title: Nat. Nanotechnol. – volume: 13 start-page: 5855 year: 2007 end-page: 5861 ident: bb0415 article-title: Phase I trial of poly- publication-title: Clin. Cancer Res. – volume: 30 start-page: 3100 year: 2009 end-page: 3109 ident: bb0535 article-title: Self-assembled oligopeptide nanostructures for co-delivery of drug and gene with synergistic therapeutic effect publication-title: Biomaterials – volume: 237 start-page: 200 year: 2001 end-page: 207 ident: bb0050 article-title: The level of hydrophobic substitution and the molecular weight of amphiphilic poly- publication-title: J. Colloid Interface Sci. – volume: 79 start-page: 165 year: 2002 end-page: 172 ident: bb0220 article-title: The effect of fatty acid substitution on the in vitro release of amphotericin B from micelles composed of poly(ethylene oxide)-block-poly(N-hexyl stearate-L-aspartamide) publication-title: J. Control. Release – volume: 55 start-page: 219 year: 1998 end-page: 229 ident: bb0275 article-title: Incorporation of water-insoluble anticancer drug into polymeric micelles and control of their particle size publication-title: J. Control. Release – volume: 2 start-page: 347 year: 2003 end-page: 360 ident: bb0265 article-title: The dawning era of polymer therapeutics publication-title: Nat. Rev. Drug Discov. – volume: 50 start-page: 79 year: 1998 end-page: 92 ident: bb0240 article-title: Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor publication-title: J. Control. Release – year: 1980 ident: bb0070 article-title: The Hydrophobic Effect: Formation of Micelles and Biological Membranes – start-page: 208 year: 2004 end-page: 209 ident: bb0625 article-title: Small molecule hydrogels based on a class of antiinflammatory agents publication-title: Chem. Commun. (Camb.) – volume: 24 start-page: 9997 year: 2008 end-page: 10004 ident: bb0180 article-title: Polymeric amphiphile branching leads to rare nano-disc shaped planar self assemblies publication-title: Langmuir – volume: 41 start-page: 1674 year: 2008 end-page: 1684 ident: bb0450 article-title: Molecular self-assembly into one-dimensional nanostructures publication-title: Acc. Chem. Res. – volume: 417 start-page: 424 year: 2002 end-page: 428 ident: bb0560 article-title: Rapidly recovering hydrogel scaffolds from self-assembling diblock copolypeptide amphiphiles publication-title: Nature – volume: 12 start-page: 192 year: 1995 end-page: 195 ident: bb0325 article-title: Physical entrapment of adriamycin in AB block copolymer micelles publication-title: Pharm. Res. – volume: 267 start-page: 71 year: 2009 end-page: 88 ident: bb0460 article-title: Emerging peptide nanomedicine to regenerate tissues and organs publication-title: J. Intern. Med. – volume: 91 start-page: 1775 year: 2004 end-page: 1781 ident: bb0285 article-title: Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin publication-title: Br. J. Cancer – volume: 52 start-page: 831 year: 2000 end-page: 835 ident: bb0340 article-title: Micelles of poly(ethylene oxide)-block-poly(N-alkyl stearate L-aspartamide): synthetic analogues of lipoproteins for drug delivery publication-title: J. Biomed. Mater. Res. – volume: 30 start-page: 2881 year: 2009 end-page: 2898 ident: bb0570 article-title: Biocompatibility of amphiphilic diblock copolypeptide hydrogels in the central nervous system publication-title: Biomaterials – volume: 100 start-page: 572 year: 2009 end-page: 579 ident: bb0290 article-title: Preclinical and clinical studies of anticancer agent-incorporating polymer micelles publication-title: Cancer Sci. – volume: 4 start-page: 262 year: 2009 end-page: 272 ident: bb0025 article-title: Nanoparticle albumin-bound (NAB) technology is a promising method for anti-cancer drug delivery publication-title: Recent Pat. Anticancer Drug Discov. – volume: 92 start-page: 1240 year: 2005 end-page: 1246 ident: bb0350 article-title: NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel publication-title: Br. J. Cancer – volume: 37 start-page: 664 year: 2008 end-page: 675 ident: bb0420 article-title: Designing peptide based nanomaterials publication-title: Chem. Soc. Rev. – volume: 99 start-page: 5133 year: 2002 end-page: 5138 ident: bb0445 article-title: Peptide-amphiphile nanofibers: a versatile scaffold for the preparation of self-assembling materials publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 64 start-page: 143 year: 2000 end-page: 153 ident: bb0185 article-title: Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl- publication-title: J. Control. Release – volume: 74 start-page: 83 year: 2001 end-page: 94 ident: bb0390 article-title: Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiammineplatinum(II) in the core publication-title: J. Control. Release – volume: 8 start-page: 327 year: 2003 end-page: 336 ident: bb0150 article-title: Catanionic surfactants: microemulsion formation and solubilization publication-title: Curr. Opin. Colloid Interface Sci. – volume: 50 start-page: 1693 year: 1990 end-page: 1700 ident: bb0115 article-title: Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer publication-title: Cancer Res. – volume: 229 start-page: 1 year: 2001 end-page: 21 ident: bb0040 article-title: Gene delivery with synthetic (non viral) carriers publication-title: Int. J. Pharm. – volume: 99 start-page: 5133 year: 2002 ident: 10.1016/j.jconrel.2012.04.046_bb0445 article-title: Peptide-amphiphile nanofibers: a versatile scaffold for the preparation of self-assembling materials publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.072699999 – volume: 30 start-page: 2881 year: 2009 ident: 10.1016/j.jconrel.2012.04.046_bb0570 article-title: Biocompatibility of amphiphilic diblock copolypeptide hydrogels in the central nervous system publication-title: Biomaterials doi: 10.1016/j.biomaterials.2009.01.056 – volume: 74 start-page: 295 year: 2001 ident: 10.1016/j.jconrel.2012.04.046_bb0280 article-title: Development of the polymer micelle carrier system for doxorubicin publication-title: J. Control. Release doi: 10.1016/S0168-3659(01)00341-8 – volume: 294 start-page: 1684 year: 2001 ident: 10.1016/j.jconrel.2012.04.046_bb0440 article-title: Self-assembly and mineralization of peptide-amphiphile nanofibers publication-title: Science doi: 10.1126/science.1063187 – volume: 33 start-page: 779 year: 1994 ident: 10.1016/j.jconrel.2012.04.046_bb0030 article-title: Clinical-studies of liposome-encapsulated doxorubicin publication-title: Acta Oncol. doi: 10.3109/02841869409083948 – volume: 30 start-page: 6202 year: 2009 ident: 10.1016/j.jconrel.2012.04.046_bb0575 article-title: Dynamic in vivo biocompatibility of angiogenic peptide amphiphile nanofibers publication-title: Biomaterials doi: 10.1016/j.biomaterials.2009.07.063 – volume: 13 start-page: 991 year: 2002 ident: 10.1016/j.jconrel.2012.04.046_bb0090 article-title: The effects of acyl chain length on the micelle properties of poly(ethylene oxide)-block-poly(N-hexyl-L-aspartamide)-acyl conjugates publication-title: J. Biomater. Sci. Polym. Ed. doi: 10.1163/156856202760319144 – volume: 87 start-page: 160 year: 1998 ident: 10.1016/j.jconrel.2012.04.046_bb0400 article-title: Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(l-lysine) block copolymer publication-title: J. Pharm. Sci. doi: 10.1021/js970304s – volume: 104 start-page: 11035 year: 2000 ident: 10.1016/j.jconrel.2012.04.046_bb0145 article-title: Microstructure and dynamics of wormlike micelles formed by mixing cationic and anionic surfactants publication-title: J. Phys. Chem. B doi: 10.1021/jp0018899 – volume: 7 start-page: 144 year: 1996 ident: 10.1016/j.jconrel.2012.04.046_bb0380 article-title: An adduct of cis-diamminedichloroplatinum(II) and poly(ethylene glycol)poly(l-lysine)-succinate: synthesis and cytotoxic properties publication-title: Bioconjug. Chem. doi: 10.1021/bc950089b – volume: 14 start-page: 449 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0395 article-title: Differential gene expression profile between PC-14 cells treated with free cisplatin and cisplatin-incorporated polymeric micelles publication-title: Bioconjug. Chem. doi: 10.1021/bc025555t – volume: 23 start-page: 8308 year: 2007 ident: 10.1016/j.jconrel.2012.04.046_bb0300 article-title: Direct formation of giant vesicles from synthetic polypeptides publication-title: Langmuir doi: 10.1021/la701038f – volume: 95 start-page: 601 year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0355 article-title: NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6603311 – volume: 64 start-page: 143 year: 2000 ident: 10.1016/j.jconrel.2012.04.046_bb0185 article-title: Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-l-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance publication-title: J. Control. Release doi: 10.1016/S0168-3659(99)00133-9 – volume: 91 start-page: 1775 year: 2004 ident: 10.1016/j.jconrel.2012.04.046_bb0285 article-title: Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6602204 – volume: 3 start-page: 244 year: 2004 ident: 10.1016/j.jconrel.2012.04.046_bb0305 article-title: Stimuli-responsive polypeptide vesicles by conformation‐specific assembly publication-title: Nat. Mater. doi: 10.1038/nmat1093 – volume: 4 start-page: 457 year: 2009 ident: 10.1016/j.jconrel.2012.04.046_bb0435 article-title: Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent publication-title: Nat. Nanotechnol. doi: 10.1038/nnano.2009.153 – volume: 52 start-page: 831 year: 2000 ident: 10.1016/j.jconrel.2012.04.046_bb0340 article-title: Micelles of poly(ethylene oxide)-block-poly(N-alkyl stearate L-aspartamide): synthetic analogues of lipoproteins for drug delivery publication-title: J. Biomed. Mater. Res. doi: 10.1002/1097-4636(20001215)52:4<831::AID-JBM29>3.0.CO;2-K – volume: 3 start-page: 629 year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0585 article-title: Pharmaceutical nanotechnology: polymeric vesicles for drug and gene delivery publication-title: Expert Opin. Drug Deliv. doi: 10.1517/17425247.3.5.629 – volume: 54 start-page: 169 year: 2002 ident: 10.1016/j.jconrel.2012.04.046_bb0045 article-title: Poly(ethylene oxide)-block-poly(l‐amino acid) micelles for drug delivery publication-title: Adv. Drug Deliv. Rev. doi: 10.1016/S0169-409X(02)00015-7 – volume: 92 start-page: 1240 year: 2005 ident: 10.1016/j.jconrel.2012.04.046_bb0350 article-title: NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6602479 – volume: 125 start-page: 15666 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0565 article-title: Unusual salt stability in highly charged diblock co-polypeptide hydrogels publication-title: J. Am. Chem. Soc. doi: 10.1021/ja0381050 – volume: 70 start-page: 3020 year: 2010 ident: 10.1016/j.jconrel.2012.04.046_bb0110 article-title: Induction of cancer cell death by self-assembling nanostructures incorporating a cytotoxic peptide publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-09-3267 – volume: 65 start-page: 271 year: 2000 ident: 10.1016/j.jconrel.2012.04.046_bb0245 article-title: Tumour vascular permeability and the EPR effect in macromolecular therapeutics: a review publication-title: J. Control. Release doi: 10.1016/S0168-3659(99)00248-5 – volume: 30 start-page: 323 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0125 article-title: Application of solid phase peptide synthesis to engineering PEO-peptide block copolymers for drug delivery publication-title: Colloids Surf. B Biointerfaces doi: 10.1016/S0927-7765(03)00125-5 – volume: 13 start-page: 5855 year: 2007 ident: 10.1016/j.jconrel.2012.04.046_bb0415 article-title: Phase I trial of poly-l-glutamate camptothecin (CT-2106) administered weekly in patients with advanced solid malignancies publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-06-2821 – year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0595 – year: 2011 ident: 10.1016/j.jconrel.2012.04.046_bb0615 article-title: Phase II study of NK105, a paclitaxel-incorporating micellar nanoparticle, for previously treated advanced or recurrent gastric cancer publication-title: Invest. New Drugs doi: 10.1007/s10637-011-9709-2 – volume: 63 start-page: 8977 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0255 article-title: Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice publication-title: Cancer Res. – volume: 267 start-page: 71 year: 2009 ident: 10.1016/j.jconrel.2012.04.046_bb0460 article-title: Emerging peptide nanomedicine to regenerate tissues and organs publication-title: J. Intern. Med. doi: 10.1111/j.1365-2796.2009.02184.x – volume: 11 start-page: 880 year: 2000 ident: 10.1016/j.jconrel.2012.04.046_bb0055 article-title: Preliminary characterization of novel amino acid based polymeric vesicles as gene and drug delivery agents publication-title: Bioconjug. Chem. doi: 10.1021/bc000052d – start-page: 131 year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0005 article-title: Polymeric vesicles – volume: 6 start-page: 3 year: 2010 ident: 10.1016/j.jconrel.2012.04.046_bb0545 article-title: Development of bioactive peptide amphiphiles for therapeutic cell delivery publication-title: Acta Biomater. doi: 10.1016/j.actbio.2009.07.031 – volume: 1 start-page: 195 year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0480 article-title: Controlled patterning of aligned self-assembled peptide nanotubes publication-title: Nat. Nanotechnol. doi: 10.1038/nnano.2006.139 – volume: 79 start-page: 165 year: 2002 ident: 10.1016/j.jconrel.2012.04.046_bb0220 article-title: The effect of fatty acid substitution on the in vitro release of amphotericin B from micelles composed of poly(ethylene oxide)-block-poly(N-hexyl stearate-L-aspartamide) publication-title: J. Control. Release doi: 10.1016/S0168-3659(01)00537-5 – volume: 118 start-page: 12515 year: 1998 ident: 10.1016/j.jconrel.2012.04.046_bb0510 article-title: Self-assembling amphiphiles for construction of protein molecular architecture publication-title: J. Am. Chem. Soc. doi: 10.1021/ja9627656 – volume: 30 start-page: 3100 year: 2009 ident: 10.1016/j.jconrel.2012.04.046_bb0535 article-title: Self-assembled oligopeptide nanostructures for co-delivery of drug and gene with synergistic therapeutic effect publication-title: Biomaterials doi: 10.1016/j.biomaterials.2009.03.006 – volume: 53 start-page: 131 year: 1998 ident: 10.1016/j.jconrel.2012.04.046_bb0235 article-title: Polymeric micelles for drug delivery: solubilization and haemolytic activity of amphotericin B publication-title: J. Control. Release doi: 10.1016/S0168-3659(97)00245-9 – volume: 15 start-page: 530 year: 2004 ident: 10.1016/j.jconrel.2012.04.046_bb0540 article-title: Promotion of peptide antimicrobial activity by fatty acid conjugation publication-title: Bioconjug. Chem. doi: 10.1021/bc0341573 – volume: 104 start-page: 593 year: 2011 ident: 10.1016/j.jconrel.2012.04.046_bb0375 article-title: A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours publication-title: Br. J. Cancer doi: 10.1038/bjc.2011.6 – volume: 85 start-page: 85 year: 1996 ident: 10.1016/j.jconrel.2012.04.046_bb0330 article-title: Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(beta-benzyl l-aspartate) block copolymer micelles publication-title: J. Pharm. Sci. doi: 10.1021/js950204r – volume: 9 start-page: 14 year: 2012 ident: 10.1016/j.jconrel.2012.04.046_bb0085 article-title: Enhanced oral absorption of hydrophobic and hydrophilic drugs using quaternary ammonium palmitoyl glycol chitosan nanoparticles publication-title: Mol. Pharm. doi: 10.1021/mp200469a – volume: 229 start-page: 1 year: 2001 ident: 10.1016/j.jconrel.2012.04.046_bb0040 article-title: Gene delivery with synthetic (non viral) carriers publication-title: Int. J. Pharm. doi: 10.1016/S0378-5173(01)00861-4 – volume: 74 start-page: 83 year: 2001 ident: 10.1016/j.jconrel.2012.04.046_bb0390 article-title: Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiammineplatinum(II) in the core publication-title: J. Control. Release doi: 10.1016/S0168-3659(01)00314-5 – start-page: 650 year: 2011 ident: 10.1016/j.jconrel.2012.04.046_bb0605 article-title: Fast gelation of self assembling peptide amphiphiles triggered by electromagnetic heating – volume: 18 start-page: 1035 year: 2001 ident: 10.1016/j.jconrel.2012.04.046_bb0385 article-title: Cisplatin-loaded polymer–metal complex micelle with time-modulated decaying property as a novel drug delivery system publication-title: Pharm. Res. doi: 10.1023/A:1010908916184 – volume: 98 start-page: 11857 year: 2001 ident: 10.1016/j.jconrel.2012.04.046_bb0505 article-title: Hierarchical self-assembly of chiral rod-like molecules as a model for peptide beta‐sheet tapes, ribbons, fibrils, and fibers publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.191250198 – volume: 19 start-page: 4332 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0525 article-title: Positively charged surfactant-like peptides self-assemble into nanostructures publication-title: Langmuir doi: 10.1021/la026526+ – volume: 78 start-page: 531 year: 2011 ident: 10.1016/j.jconrel.2012.04.046_bb0195 article-title: Use of conventional surfactant media as surrogates for FaSSIF in simulating in vivo dissolution of BCS class II drugs publication-title: Eur. J. Pharm. Biopharm. doi: 10.1016/j.ejpb.2011.02.007 – volume: 17 start-page: 607 year: 2000 ident: 10.1016/j.jconrel.2012.04.046_bb0270 article-title: Methotrexate esters of poly(ethylene oxide)-block-poly(2-hydroxyethyl-L-aspartamide). Part I: effects of the level of methotrexate conjugation on the stability of micelles and on drug release publication-title: Pharm. Res. doi: 10.1023/A:1007529218802 – volume: 37 start-page: 664 year: 2008 ident: 10.1016/j.jconrel.2012.04.046_bb0420 article-title: Designing peptide based nanomaterials publication-title: Chem. Soc. Rev. doi: 10.1039/b609047h – year: 1980 ident: 10.1016/j.jconrel.2012.04.046_bb0070 – volume: 12 start-page: 192 year: 1995 ident: 10.1016/j.jconrel.2012.04.046_bb0325 article-title: Physical entrapment of adriamycin in AB block copolymer micelles publication-title: Pharm. Res. doi: 10.1023/A:1016266523505 – volume: 93 start-page: 193 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0105 article-title: In vitro and in vivo gene transfer with poly(amino acid) vesicles publication-title: J. Control. Release doi: 10.1016/j.jconrel.2003.08.022 – volume: 16 start-page: 295 year: 1995 ident: 10.1016/j.jconrel.2012.04.046_bb0320 article-title: Block copolymer micelles as long-circulating drug vehicles publication-title: Adv. Drug Deliv. Rev. doi: 10.1016/0169-409X(95)00031-2 – volume: 26 start-page: 2301 year: 2010 ident: 10.1016/j.jconrel.2012.04.046_bb0080 article-title: The molecular shape of poly(propylenimine) dendrimers has a profound effect on their self assembly publication-title: Langmuir doi: 10.1021/la9027282 – volume: 8 start-page: 327 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0150 article-title: Catanionic surfactants: microemulsion formation and solubilization publication-title: Curr. Opin. Colloid Interface Sci. doi: 10.1016/S1359-0294(03)00081-5 – volume: 44 start-page: 5252 year: 2005 ident: 10.1016/j.jconrel.2012.04.046_bb0530 article-title: Membrane-mimetic nanocarriers formed by a dipalmitoylated cell-penetrating peptide publication-title: Angew. Chem. Int. Ed Engl. doi: 10.1002/anie.200500519 – volume: volumes I, II and III year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0590 – volume: 7 start-page: 3452 year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0170 article-title: Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude publication-title: Biomacromolecules doi: 10.1021/bm0604000 – volume: 7 start-page: 1509 year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0175 article-title: Polyelectrolyte nanoparticles with high drug loading enhance the oral uptake of hydrophobic compounds publication-title: Biomacromolecules doi: 10.1021/bm060130l – volume: 7 start-page: S423 year: 2010 ident: 10.1016/j.jconrel.2012.04.046_bb0230 article-title: In silico modelling of drug–polymer interactions for pharmaceutical formulations publication-title: J. R. Soc. Interface doi: 10.1098/rsif.2010.0190.focus – volume: 51 start-page: 169 year: 1998 ident: 10.1016/j.jconrel.2012.04.046_bb0370 article-title: Clonazepam release from core-shell type nanoparticles in vitro publication-title: J. Control. Release doi: 10.1016/S0168-3659(97)00163-6 – volume: 47 start-page: 10365 year: 2008 ident: 10.1016/j.jconrel.2012.04.046_bb0515 article-title: MagicWand: a single, designed peptide that assembles to stable, ordered alpha-helical fibers publication-title: Biochemistry doi: 10.1021/bi801072s – volume: 50 start-page: 1693 year: 1990 ident: 10.1016/j.jconrel.2012.04.046_bb0115 article-title: Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer publication-title: Cancer Res. – volume: 97 start-page: 170 year: 2007 ident: 10.1016/j.jconrel.2012.04.046_bb0405 article-title: A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6603855 – volume: 18 year: 2002 ident: 10.1016/j.jconrel.2012.04.046_bb0600 article-title: Wormy micelles formed by synergistic self-assembly in mixtures of anionic and cationic surfactants publication-title: Langmuir doi: 10.1021/la0115583 – volume: 29 start-page: 17 year: 1994 ident: 10.1016/j.jconrel.2012.04.046_bb0210 article-title: Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer–adriamycin conjugates publication-title: J. Control. Release doi: 10.1016/0168-3659(94)90118-X – volume: 2 start-page: 347 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0265 article-title: The dawning era of polymer therapeutics publication-title: Nat. Rev. Drug Discov. doi: 10.1038/nrd1088 – volume: 365 start-page: 1417 year: 2007 ident: 10.1016/j.jconrel.2012.04.046_bb0455 article-title: Supramolecular self-assembly codes for functional structures publication-title: Philos. Transact. A Math. Phys. Eng. Sci. doi: 10.1098/rsta.2007.2024 – volume: 94 start-page: 1 year: 2010 ident: 10.1016/j.jconrel.2012.04.046_bb0065 article-title: Self-assembly of peptide amphiphiles: from molecules to nanostructures to biomaterials publication-title: Biopolymers doi: 10.1002/bip.21328 – volume: 519 start-page: 81 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0410 article-title: Poly-(L)-glutamic acid–paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: characterization, preclinical pharmacology, and preliminary clinical data publication-title: Adv. Exp. Med. Biol. doi: 10.1007/0-306-47932-X_6 – volume: 14 start-page: 4074 year: 1998 ident: 10.1016/j.jconrel.2012.04.046_bb0225 article-title: Large internal structures of micelles of triblock copolymers with small insoluble molecules in their cores publication-title: Langmuir doi: 10.1021/la980104b – volume: 267 start-page: 71 year: 2010 ident: 10.1016/j.jconrel.2012.04.046_bb0490 article-title: Emerging peptide nanomedicine to regenerate tissues and organs publication-title: J. Intern. Med. doi: 10.1111/j.1365-2796.2009.02184.x – volume: 6 start-page: 865 year: 2002 ident: 10.1016/j.jconrel.2012.04.046_bb0425 article-title: Design of nanostructured biological materials through self-assembly of peptides and proteins publication-title: Curr. Opin. Chem. Biol. doi: 10.1016/S1367-5931(02)00391-5 – volume: 6 start-page: 5064 year: 2010 ident: 10.1016/j.jconrel.2012.04.046_bb0555 article-title: Fibronectin-mimetic peptide-amphiphile nanofiber gels support increased cell adhesion and promote ECM production publication-title: Soft Matter doi: 10.1039/c0sm00321b – volume: 41 start-page: 1674 year: 2008 ident: 10.1016/j.jconrel.2012.04.046_bb0450 article-title: Molecular self-assembly into one-dimensional nanostructures publication-title: Acc. Chem. Res. doi: 10.1021/ar8000926 – year: 2012 ident: 10.1016/j.jconrel.2012.04.046_bb0620 article-title: A Prodrug Nanoparticle Approach for the Oral Delivery of Leucine5-enkephalin to the Brain publication-title: Mol. Pharm. doi: 10.1021/mp300009u – volume: 100 start-page: 572 year: 2009 ident: 10.1016/j.jconrel.2012.04.046_bb0290 article-title: Preclinical and clinical studies of anticancer agent-incorporating polymer micelles publication-title: Cancer Sci. doi: 10.1111/j.1349-7006.2009.01103.x – volume: 90 start-page: 3334 year: 1993 ident: 10.1016/j.jconrel.2012.04.046_bb0430 article-title: Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.90.8.3334 – year: 2009 ident: 10.1016/j.jconrel.2012.04.046_bb0035 – volume: 188 start-page: 49 year: 1999 ident: 10.1016/j.jconrel.2012.04.046_bb0365 article-title: Adriamycin release from flower-type polymeric micelle based on star-block copolymer composed of poly(gamma-benzyl l-glutamate) as the hydrophobic part and poly(ethylene oxide) as the hydrophilic part publication-title: Int. J. Pharm. doi: 10.1016/S0378-5173(99)00202-1 – volume: 93 start-page: 678 year: 2005 ident: 10.1016/j.jconrel.2012.04.046_bb0260 article-title: Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6602772 – volume: 56 start-page: 285 year: 1998 ident: 10.1016/j.jconrel.2012.04.046_bb0310 article-title: In vitro dissociation of antifungal efficacy and toxicity for amphotericin B-loaded poly(ethylene oxide)-block-poly(beta benzyl laspartate) micelles publication-title: J. Control. Release doi: 10.1016/S0168-3659(98)00095-9 – volume: 8 start-page: 1 year: 2010 ident: 10.1016/j.jconrel.2012.04.046_bb0020 article-title: Nanoparticle albumin-bound (nab (TM))-paclitaxel: improving efficacy and tolerability by targeted drug delivery in metastatic breast cancer publication-title: EJC Suppl. doi: 10.1016/S1359-6349(10)70002-1 – volume: 37 start-page: 9114 year: 2004 ident: 10.1016/j.jconrel.2012.04.046_bb0120 article-title: Self-assembly of cetyl linear polyethylenimine to give micelles, vesicles, and dense nanoparticles publication-title: Macromolecules doi: 10.1021/ma049042o – volume: 1 start-page: 387 year: 2005 ident: 10.1016/j.jconrel.2012.04.046_bb0485 article-title: Self-assembling peptide amphiphile nanofiber matrices for cell entrapment publication-title: Acta Biomater. doi: 10.1016/j.actbio.2005.04.002 – volume: 31 start-page: 288 year: 1998 ident: 10.1016/j.jconrel.2012.04.046_bb0610 article-title: Novel polyion complex micelles entrapping enzyme molecules in the core. Preparation of narrowly-distributed micelles from lysozyme and poly(ethylene glycol)-poly(aspartic acid) block copolymer in aqueous medium publication-title: Macromolecules doi: 10.1021/ma971277v – volume: 22 start-page: 3259 year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0550 article-title: Design of a novel fibronectin-mimetic peptide-amphiphile for functionalized biomaterials publication-title: Langmuir doi: 10.1021/la052756n – volume: 15 start-page: 377 year: 1999 ident: 10.1016/j.jconrel.2012.04.046_bb0250 article-title: Preparation and characterization of self-assembled polymer–metal complex micelle from cis-dichlorodiammineplatinum(II) and poly(ethylene glycol)‐poly(α, β-aspartic acid) block copolymer in an aqueous medium publication-title: Langmuir doi: 10.1021/la980572l – volume: 128 start-page: 7291 year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0465 article-title: Self-assembly of peptide-amphiphile nanofibers: the roles of hydrogen bonding and amphiphilic packing publication-title: J. Am. Chem. Soc. doi: 10.1021/ja060573x – volume: 90 start-page: 363 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0165 article-title: Poly(L-histidine)-PEG block copolymer micelles and pH-induced destabilization publication-title: J. Control. Release doi: 10.1016/S0168-3659(03)00205-0 – start-page: 208 year: 2004 ident: 10.1016/j.jconrel.2012.04.046_bb0625 article-title: Small molecule hydrogels based on a class of antiinflammatory agents publication-title: Chem. Commun. (Camb.) doi: 10.1039/b310574a – year: 2006 ident: 10.1016/j.jconrel.2012.04.046_bb0010 – volume: 55 start-page: 219 year: 1998 ident: 10.1016/j.jconrel.2012.04.046_bb0275 article-title: Incorporation of water-insoluble anticancer drug into polymeric micelles and control of their particle size publication-title: J. Control. Release doi: 10.1016/S0168-3659(98)00054-6 – year: 1991 ident: 10.1016/j.jconrel.2012.04.046_bb0135 – volume: 87 start-page: 23 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0215 article-title: Relative aggregation state and hemolytic activity of amphotericin B encapsulated by poly(ethylene oxide)-block-poly(N-hexyl-L-aspartamide)-acyl conjugate micelles: effects of acyl chain length publication-title: J. Control. Release doi: 10.1016/S0168-3659(02)00347-4 – volume: 24 start-page: 4495 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0130 article-title: Polyion complex micelles from plasmid DNA and poly(ethylene glycol)-poly(l-lysine) block copolymer as serum-tolerable polyplex system: physicochemical properties of micelles relevant to gene transfection efficiency publication-title: Biomaterials doi: 10.1016/S0142-9612(03)00347-8 – volume: 20 start-page: 357 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0315 article-title: Polymeric micelles for delivery of poorly water-soluble compounds publication-title: Crit. Rev. Ther. Drug Carrier Syst. doi: 10.1615/CritRevTherDrugCarrierSyst.v20.i5.20 – volume: 16 start-page: 7859 year: 2000 ident: 10.1016/j.jconrel.2012.04.046_bb0095 article-title: A new class of amphiphilic poly-l-lysine based polymers forms nanoparticles on probe sonication in aqueous media publication-title: Langmuir doi: 10.1021/la000633r – volume: 23 start-page: 2058 year: 2007 ident: 10.1016/j.jconrel.2012.04.046_bb0520 article-title: Stabilization of peptide fibrils by hydrophobic interaction publication-title: Langmuir doi: 10.1021/la0625345 – volume: 7 start-page: 171 year: 1999 ident: 10.1016/j.jconrel.2012.04.046_bb0360 article-title: Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system publication-title: J. Drug Target. doi: 10.3109/10611869909085500 – volume: 28 start-page: 3814 year: 2008 ident: 10.1016/j.jconrel.2012.04.046_bb0580 article-title: Self-assembling nanofibers inhibit glial scar formation and promote axon elongation after spinal cord injury publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.0143-08.2008 – volume: 24 start-page: 9997 year: 2008 ident: 10.1016/j.jconrel.2012.04.046_bb0180 article-title: Polymeric amphiphile branching leads to rare nano-disc shaped planar self assemblies publication-title: Langmuir doi: 10.1021/la8007848 – volume: 35 start-page: 535 year: 2007 ident: 10.1016/j.jconrel.2012.04.046_bb0495 article-title: Three-dimensional cell culture of chondrocytes on modified di-phenylalanine scaffolds publication-title: Biochem. Soc. Trans. doi: 10.1042/BST0350535 – volume: 108 start-page: 226 year: 2005 ident: 10.1016/j.jconrel.2012.04.046_bb0060 article-title: Preparation and characterization of biodegradable nanoparticles based on poly(gamma-glutamic acid) with l-phenylalanine as a protein carrier publication-title: J. Control. Release doi: 10.1016/j.jconrel.2005.08.003 – volume: 4 start-page: 750 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0205 article-title: Amphotericin B encapsulated in micelles based on poly(ethylene oxide)-block-poly(l‐amino acid) derivatives exerts reduced in vitro hemolysis but maintains potent in vivo antifungal activity publication-title: Biomacromolecules doi: 10.1021/bm0257614 – volume: 417 start-page: 424 year: 2002 ident: 10.1016/j.jconrel.2012.04.046_bb0560 article-title: Rapidly recovering hydrogel scaffolds from self-assembling diblock copolypeptide amphiphiles publication-title: Nature doi: 10.1038/417424a – volume: 237 start-page: 200 year: 2001 ident: 10.1016/j.jconrel.2012.04.046_bb0050 article-title: The level of hydrophobic substitution and the molecular weight of amphiphilic poly-l-lysine-based polymers strongly affects their assembly into polymeric bilayer vesicles publication-title: J. Colloid Interface Sci. doi: 10.1006/jcis.2001.7463 – volume: 300 start-page: 625 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0475 article-title: Casting metal nanowires within discrete self-assembled peptide nanotubes publication-title: Science doi: 10.1126/science.1082387 – volume: 92 start-page: 1343 year: 2003 ident: 10.1016/j.jconrel.2012.04.046_bb0335 article-title: Amphiphilic block copolymers for drug delivery publication-title: J. Pharm. Sci. doi: 10.1002/jps.10397 – volume: 17 start-page: 631 year: 2001 ident: 10.1016/j.jconrel.2012.04.046_bb0200 article-title: Controls on polymer molecular weight may be used to control the size of palmitoyl glycol chitosan polymeric vesicles publication-title: Langmuir doi: 10.1021/la001078w – volume: 50 start-page: 79 year: 1998 ident: 10.1016/j.jconrel.2012.04.046_bb0240 article-title: Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor publication-title: J. Control. Release doi: 10.1016/S0168-3659(97)00115-6 – volume: 77 start-page: 155 year: 2001 ident: 10.1016/j.jconrel.2012.04.046_bb0345 article-title: Micelles self-assembled from poly(ethylene oxide)-block-poly(N-hexyl stearate L-aspartamide) by a solvent evaporation method: effect on the solubilization and haemolytic activity of amphotericin B publication-title: J. Control. Release doi: 10.1016/S0168-3659(01)00477-1 – volume: 133 start-page: 3677 year: 2011 ident: 10.1016/j.jconrel.2012.04.046_bb0100 article-title: Atomistic molecular dynamics simulations of peptide amphiphile self-assembly into cylindrical nanofibers publication-title: J. Am. Chem. Soc. doi: 10.1021/ja110966y – volume: 4 start-page: 262 year: 2009 ident: 10.1016/j.jconrel.2012.04.046_bb0025 article-title: Nanoparticle albumin-bound (NAB) technology is a promising method for anti-cancer drug delivery publication-title: Recent Pat. Anticancer Drug Discov. doi: 10.2174/157489209789206869 – volume: 245 start-page: 1371 year: 1989 ident: 10.1016/j.jconrel.2012.04.046_bb0155 article-title: Spontaneous vesicle formation in aqueous mixtures of single-tailed surfactants publication-title: Science doi: 10.1126/science.2781283 |
| SSID | ssj0005347 |
| Score | 2.4408298 |
| SecondaryResourceType | review_article |
| Snippet | The formulation of drug compounds into medicines will increasingly rely on the use of specially tailored molecules, which fundamentally alter the drug's... |
| SourceID | proquest pubmed crossref fao elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 523 |
| SubjectTerms | Acids Amino acids Amino Acids - administration & dosage Amino Acids - chemistry Animals Antineoplastic Agents - administration & dosage Antineoplastic Agents - chemistry composite polymers Controlled release Copolymers Drug delivery Drug Delivery Systems drugs Gene transfer genes Humans hydrophilicity Hydrophobicity Micelles nanofibers nanoparticles neoplasms Peptide amphiphiles Peptides - administration & dosage Peptides - chemistry Pharmacokinetics Polymeric micelles Polymeric vesicles Polymers - administration & dosage Polymers - chemistry Self Self-assembly Solid polymeric nanoparticles Vesicles |
| Title | Amphiphilic poly(l-amino acids) — New materials for drug delivery |
| URI | https://dx.doi.org/10.1016/j.jconrel.2012.04.046 https://www.ncbi.nlm.nih.gov/pubmed/22613882 https://www.proquest.com/docview/1021126138 https://www.proquest.com/docview/1034828427 https://www.proquest.com/docview/1686717035 |
| Volume | 161 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1fa9swEBdd-7KXsbXbmv0pKoyyQZU49lmWH0NoSTsohTbQNyHLUnHI7JA0D3kZ-xD7hPsku4vtpntoCwO_2EiydCedfne6OzH2BbyBVCkQNopiAYkEkfW9EgY1Fm_DiCAEeVtcyNEYzm_imy02bGNhyK2ykf21TF9L6-ZLr6Fmb1YUvSsEKwrbSvvEaNxpKYIdf4ZzuvvzgZtHBHXItFSCSm-ieHqT7gR1zrmjEwgyCQI-8rH96YU31eModL0bnb5mrxoYyQd1T9-wLVfusqPLOg_16phfb8KqFsf8iF9uMlSv9thwgDwsZmRLsXxWTVdfp8L8KMqKG1vki2_8z6_fHMUfRzhbz1CO2Jbn8-Utz92UXDlWb9n49OR6OBLNbQrC0qUFIk7AUjI8hyqVzLM0teBjnwRpFKQeEPVJVIZRG-srE8a4GLPUewRPYCPInUrC6B3bLqvS7TNulIoT563KDMIp6TMnIc-8DzwCKJQAHQYtDbVtUo3TjRdT3fqUTXRDek2k1wHgIzuse19tVufaeK6Cahmk_5k0GveD56ruI0O1uUVRqsdXIRl-UDjJJMHeH7Zc1rjW6ADFlK5aLjRdg95HlTNST5WhdEEKwqfakZRVEGVt3GHv62l0P-Bw3b4KP_z_2D6yl_RGFugw-MS27-ZL9xmh0112sF4bB2xncPZ9dPEXcDsUxg |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1fa9swED_a9GF7Ge3-NdvaaTDKBnXj2LIsP4awkq5dKDSBvglZlopDZoekechbP8Q-4T7J7mK7oQ9tYeAn2ycknXT3O-n-AHzlTvNESu6ZMIw8HgvupV0nPY0WizNBSBCCvC2GYjDmP6-j6y3oN7Ew5FZZy_5Kpq-ldf2mU89mZ5bnnSsEKxLbSrrEaNS027BD2amiFuz0zs4Hw42nR8irqGkhPSLYBPJ0JicTNDvnli4h6FSQ4yMeU1HbTpePA9G1QjrdhVc1kmS9qrN7sGWL13B0WaWiXh2z0SayanHMjtjlJkn16g30e8jGfEbHKYbNyunq29TTv_OiZNrk2eI7-3v3h6EEZIhoq0XKEN6ybL68YZmdkjfH6i2MT3-M-gOvLqjgGapb4EUxN5QPz6JVJbI0SQx3kYv9JPQTxxH4CbSH0SDrSh1EuB_TxDnET9yEPLMyDsJ30CrKwu4D01JGsXVGphoRlXCpFTxLnfMdYigUAm3gzRwqU2cbp6IXU9W4lU1UPfWKpl75HB_RhpN7slmVbuM5AtkwSD1YNwpVwnOk-8hQpW9QmqrxVUBnPyifRBxj7780XFa43egORRe2XC4UVULvotUZyqf-oYxBkgdPtSMosSCK26gN76tldD_gYN2-DD78_9g-w4vB6NeFujgbnn-El_SFDqQD_xO0budLe4BI6jY9rHfKP-O_F3c |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Amphiphilic+poly%28l-amino+acids%29+%E2%80%94+New+materials+for+drug+delivery&rft.jtitle=Journal+of+controlled+release&rft.au=Lalatsa%2C+Aikaterini&rft.au=Sch%C3%A4tzlein%2C+Andreas+G.&rft.au=Mazza%2C+Mariarosa&rft.au=Le%2C+Thi+Bich+Hang&rft.date=2012-07-20&rft.pub=Elsevier+B.V&rft.issn=0168-3659&rft.eissn=1873-4995&rft.volume=161&rft.issue=2&rft.spage=523&rft.epage=536&rft_id=info:doi/10.1016%2Fj.jconrel.2012.04.046&rft.externalDocID=S0168365912004063 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0168-3659&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0168-3659&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0168-3659&client=summon |