Genetic modifiers of Huntington disease differentially influence motor and cognitive domains - Lee, Jong-Min; Huang, Yuan; Orth, Michael; Gillis, Tammy; Siciliano, Jacqueline; Hong, Eunpyo; Mysore, Jayalakshmi Srinidhi; Lucente, Diane; Wheeler, Vanessa C.; Seong, Ihn Sik; McLean, Zachariah L.; Mills, James A.; et al. (American journal of human genetics, 2022)
Keywords: age at onset; CAG repeat; Cognition; disease modification; DNA; DNA maintenance; DNA repair; genetic modifier; Genome-Wide Association Study; Humans; Huntingtin Protein - genetics; Huntington disease; Huntington Disease - genetics; Huntington Disease - pathology; polyglutamine disease; somatic expansion; trinucleotide repeat; Trinucleotide Repeat Expansion; somatic expansion; Huntington disease; DNA maintenance; trinucleotide repeat; CAG repeat; age at onset; DNA repair; genetic modifier; polyglutamine disease; disease modification