Recent H3N2 Viruses Have Evolved Specificity for Extended, Branched Human-type Receptors, Conferring Potential for Increased Avidity - Peng, Wenjie; de Vries, Robert P.; Grant, Oliver C.; Thompson, Andrew J.; McBride, Ryan; Tsogtbaatar, Buyankhishig; Lee, Peter S.; Razi, Nahid; Wilson, Ian A.; Woods, Robert J.; Paulson, James C. (Cell host & microbe, 2017)
Keywords: airway; Animals; bidentate binding; Cell Line; chemo-enzymatic synthesis; Dogs; extended branched glycans; Galactans - metabolism; H3N2; HEK293 Cells; hemagglutinin; Hemagglutinin Glycoproteins, Influenza Virus - metabolism; Humans; Influenza A Virus, H1N1 Subtype - genetics; Influenza A Virus, H1N1 Subtype - metabolism; Influenza A Virus, H3N2 Subtype - genetics; Influenza A Virus, H3N2 Subtype - metabolism; Influenza A Virus, H3N8 Subtype - metabolism; Influenza A Virus, H5N1 Subtype - metabolism; influenza virus; Madin Darby Canine Kidney Cells; Molecular Dynamics Simulation; N-Acetylneuraminic Acid - metabolism; poly-N-acetyl-lactosamine; Polysaccharides - metabolism; receptor specificity; Receptors, Virus - metabolism; sialoside microarray; Species Specificity; Virus Attachment; sialoside microarray; chemo-enzymatic synthesis; poly-N-acetyl-lactosamine; bidentate binding; hemagglutinin; airway; influenza virus; receptor specificity; extended branched glycans; H3N2