The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical
HIV-1 integrase (IN) catalyzes viral DNA integration into the host genome and facilitates multifunctional steps including virus particle maturation. Competency of IN to form multimeric assemblies is functionally critical, presenting an approach for anti-HIV strategies. Multimerization of IN depends...
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Published in | Structure (London) Vol. 24; no. 11; pp. 1936 - 1946 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Ltd
01.11.2016
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Subjects | |
Online Access | Get full text |
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