Response to cocaine, alone and in combination with methylphenidate, in cocaine abusers with ADHD

• Published in: Drug and alcohol dependence Vol. 82; no. 2; pp. 158 - 167
• Main Authors: Collins, Stephanie L., Levin, Frances R., Foltin, Richard W., Kleber, Herbert D., Evans, Suzette M.
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 28.04.2006; Elsevier Science
• Subjects: Addictive behaviors; ADHD; Administration, Oral; Adrenergic Agents - administration & dosage; Adrenergic Agents - pharmacology; Adult; Adult and adolescent clinical studies; Attention Deficit Disorder with Hyperactivity - complications; Attention Deficit Disorder with Hyperactivity - psychology; Attention deficit hyperactivity disorder; Biological and medical sciences; Choice Behavior; Cocaine; Cocaine - pharmacology; Cocaine-Related Disorders - complications; Cocaine-Related Disorders - psychology; Computers; Delayed-Action Preparations; Dosage; Drug addiction; Human; Humans; Medical sciences; Methylphenidate; Methylphenidate - administration & dosage; Methylphenidate - pharmacology; Neuropharmacology; Pharmacology. Drug treatments; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease); Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychopharmacology; Self-administration; Subjective effects; Subjective experiences; Toxicology; Human; ADHD; Self-administration; Cocaine; Subjective effects; Methylphenidate; Drug addiction; CNS stimulant; Hyperactivity; Psychotropic; Psychology; Self administration; Response; Ester; Attentional disorder; Addiction; Piperidine derivatives; Drug of abuse; Attention disorder with hyperactivity; Psychiatry

Attention deficit hyperactivity disorder (ADHD) is prevalent in adult cocaine abusers. Yet, it remains to be determined how the response to cocaine differs in cocaine abusers with ADHD compared to cocaine abusers without ADHD. Further, since ADHD is commonly treated with stimulants, such as methylph...