Intravascular tissue factor pathway--a model for rapid initiation of coagulation within the blood vessel

• Published in: Thrombosis and haemostasis Vol. 89; no. 1; p. 3
• Main Authors: Engelmann, Bernd, Luther, Thomas, Müller, Ingrid
• Format: Journal Article
• Language: English
• Published: Germany 01.01.2003
• Subjects: Blood Coagulation; Blood Platelets - chemistry; Blood Platelets - metabolism; Blood Platelets - ultrastructure; Cell Communication; Humans; Thromboplastin - metabolism; Thromboplastin - physiology

The loss of blood through vessel wall ruptures is initially prevented by the rapid adhesion of platelets to the subendothelium, and the formation of a thrombus consisting of platelets and different types of leukocytes. Concomitantly, the coagulation process is thought to be activated by vascular wal...