PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease - Moreno-Fernandez, Maria E.; Giles, Daniel A.; Oates, Jarren R.; Chan, Calvin C.; Damen, Michelle S.M.A.; Doll, Jessica R.; Stankiewicz, Traci E.; Chen, Xiaoting; Chetal, Kashish; Karns, Rebekah; Weirauch, Matthew T.; Romick-Rosendale, Lindsey; et al. (Cell metabolism, 2021)
Keywords: Animals; Carrier Proteins - immunology; Cell Line; cellular metabolism; CXCR3; Female; glycolysis; Humans; IFNγ; liver; Male; Membrane Proteins - immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; NAFLD; Non-alcoholic Fatty Liver Disease - immunology; obesity; PKM; Pyruvate Kinase - immunology; Receptors, CXCR3 - immunology; T cell; Th17 Cells - cytology; Th17 Cells - immunology; Thyroid Hormone-Binding Proteins; Thyroid Hormones - immunology; TNF; IFNγ; NAFLD; PKM; liver; CXCR3; T cell; cellular metabolism; glycolysis; TNF; obesity