Chemical composition and pharmacological mechanism of Qingfei Paidu Decoction and Ma Xing Shi Gan Decoction against Coronavirus Disease 2019 (COVID-19): In silico and experimental study - Yang, Ruocong; Liu, Hao; Bai, Chen; Wang, Yingchao; Zhang, Xiaohui; Guo, Rui; Wu, Siying; Wang, Jianxun; Leung, Elaine; Chang, Hang; Li, Peng; Liu, Tiegang; et al. (Pharmacological research, 2020)
Keywords: Animals; Anti-Inflammatory Agents - analysis; Anti-Inflammatory Agents - pharmacology; Betacoronavirus - drug effects; Cells, Cultured; Computer Simulation; Corona virus disease 2019; Coronavirus Infections - drug therapy; Coronavirus Infections - genetics; COVID-19; Drugs, Chinese Herbal - analysis; Drugs, Chinese Herbal - pharmacology; Drugs, Chinese Herbal - therapeutic use; Gene Expression - drug effects; Glycyrrhizic Acid - pharmacology; Humans; Interleukin-6 - metabolism; Lipopeptides - antagonists & inhibitors; Lipopeptides - pharmacology; Lipopolysaccharides; Ma Xing Shi Gan Decoction; Male; Network pharmacology; Pandemics; Pneumonia - chemically induced; Pneumonia - metabolism; Pneumonia, Viral - drug therapy; Pneumonia, Viral - genetics; Qingfei Paidu Decoction; Rats; SARS-CoV-2; Signal Transduction - drug effects; Thrombin - metabolism; Toll-Like Receptors - metabolism; Traditional Chinese medicine; Hesperidin (PubChem CID: 10621); Baicalin (PubChem CID: 64982); Qingfei Paidu Decoction; Corona virus disease 2019; Ma Xing Shi Gan Decoction; Traditional Chinese medicine; Glycyrrhizic acid (PubChem CID: 14982); Neohesperidin (PubChem CID: 442439); Network pharmacology; Narirutin (PubChem CID: 442431); Amygdalin (PubChem CID: 656516); Ephedrine (PubChem CID: 9294)