Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells

• Published in: American journal of physiology: endocrinology and metabolism Vol. 291; no. 5; pp. E1124 - E1130
• Main Authors: Johansson, Git S, Arnqvist, Hans J
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.11.2006
• Subjects: Animals; Aorta, Thoracic - cytology; Binding sites; Carbon Radioisotopes; Cell biology; Cellbiologi; Cells, Cultured; Cellular biology; deoxyribonucleic acid synthesis; Dimerization; Glucose; Glucose - pharmacokinetics; glucose metabolism; Hypoglycemic Agents - metabolism; Hypoglycemic Agents - pharmacology; immunoprecipitation; Insulin; Insulin - metabolism; Insulin - pharmacology; insulin-like growth factor I; Insulin-Like Growth Factor I - metabolism; Insulin-Like Growth Factor I - pharmacology; Iodine Radioisotopes; ligand binding; Ligands; Male; Medical cell biology; MEDICIN; MEDICINE; Medicinsk cellbiologi; Metabolism; Morfologi, cellbiologi, patologi; Morphology, cell biology, pathology; Muscle, Smooth, Vascular - cytology; Muscle, Smooth, Vascular - metabolism; Phosphorylation; Rats; Rats, Sprague-Dawley; receptor phosphorylation; Receptor, IGF Type 1 - chemistry; Receptor, IGF Type 1 - metabolism; Receptor, Insulin - chemistry; Receptor, Insulin - metabolism; Studies; Thymidine - pharmacokinetics; Tritium

1 Department of Biomedicine and Surgery, Division of Cell Biology; and 2 Diabetes Research Centre, Faculty of Health Sciences, Linköping University, Linköping, Sweden Submitted 18 November 2005 ; accepted in final form 20 June 2006 Insulin and insulin-like growth factor I (IGF-I) are known to affect...