Comparative transmissibility of SARS-CoV-2 variants Delta and Alpha in New England, USA

• Published in: Cell reports. Medicine Vol. 3; no. 4; p. 100583
• Main Authors: Earnest, Rebecca, Uddin, Rockib, Matluk, Nicholas, Renzette, Nicholas, Turbett, Sarah E., Siddle, Katherine J., Loreth, Christine, Adams, Gordon, Tomkins-Tinch, Christopher H., Petrone, Mary E., Rothman, Jessica E., Breban, Mallery I., Koch, Robert Tobias, Billig, Kendall, Fauver, Joseph R., Vogels, Chantal B.F., Bilguvar, Kaya, De Kumar, Bony, Landry, Marie L., Peaper, David R., Omerza, Greg, Grieser, Heather, Meak, Sim, Martha, John, Dewey, Hannah B., King, Ewa, Huard, Richard C., Novitsky, Vlad, Darpolor, Josephine, Manne, Akarsh, Kantor, Rami, Smole, Sandra C., Brown, Catherine M., Fink, Timelia, Lang, Andrew S., Gallagher, Glen R., Pitzer, Virginia E., Sabeti, Pardis C., Gabriel, Stacey, MacInnis, Bronwyn L., Altajar, Ahmad, DeJesus, Alexandra, Brito, Anderson, Watkins, Anne E., Muyombwe, Anthony, Blumenstiel, Brendan S., Neal, Caleb, Kalinich, Chaney C., Liu, Chen, Castaldi, Christopher, Pearson, Claire, Bernard, Clare, Nolet, Corey M., Buzby, Erika, Laszlo, Eva, Reagan, Faye L., Vicente, Gina, Rooke, Heather M., Munger, Heidi, Johnson, Hillary, Tikhonova, Irina R., Ott, Isabel M., Razeq, Jafar, Meldrim, James C., Brown, Jessica, Wang, Jianhui, Vostok, Johanna, Beauchamp, John P., Grimsby, Jonna L., Messer, Katelyn S., Vernest, Kyle, Green, Lisa M., Webber, Lori, Gagne, Luc, Ray, Marianne C., Fisher, Marissa E., Barter, Mary, Lee, Matthew D., DeFelice, Matthew T., Cipicchio, Michelle C., Smith, Natasha L., Fitzgerald, Nicholas A., Kerantzas, Nicholas, Hui, Pei, Harrington, Rachel, Haye, Rashida, Lynch, Ryan, Cofsky, Seana, Clancy, Selina, Mane, Shrikant, Ash, Stephanie, Baez, Stephanie, Fleming, Steve, Murphy, Steven, Alpert, Tara, Mandese, Zoe M., Adams, Mark D., Park, Daniel J., Lemieux, Jacob E., Grubaugh, Nathan D.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 19.04.2022; Elsevier
• Subjects: COVID-19; COVID-19 - epidemiology; genomic epidemiology; Humans; New England - epidemiology; Public Health; SARS-CoV-2; SARS-CoV-2 - genetics; transmissibility; variant of concern; viral emergence; viral sequencing; VOC; New England; COVID-19; SARS-CoV-2; viral emergence; genomic epidemiology; transmissibility; viral sequencing; variant of concern; VOC

The SARS-CoV-2 Delta variant rose to dominance in mid-2021, likely propelled by an estimated 40%–80% increased transmissibility over Alpha. To investigate if this ostensible difference in transmissibility is uniform across populations, we partner with public health programs from all six states in Ne...