Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis - Collins, Angela C.; Cai, Haocheng; Li, Tuo; Franco, Luis H.; Li, Xiao-Dong; Nair, Vidhya R.; Scharn, Caitlyn R.; Stamm, Chelsea E.; Levine, Beth; Chen, Zhijian J.; Shiloh, Michael U. (Cell host & microbe, 2015)
Keywords: Animals; Autophagy; DNA, Bacterial - metabolism; DNA-Binding Proteins - metabolism; Host-Pathogen Interactions - immunology; Humans; Immunity, Innate; Interferon-beta - immunology; Interferon-beta - metabolism; Macrophages - metabolism; Macrophages - microbiology; Membrane Proteins - metabolism; Mice, Inbred C57BL; Mice, Mutant Strains; Mycobacterium tuberculosis - genetics; Nucleotidyltransferases - genetics; Nucleotidyltransferases - metabolism; Proto-Oncogene Proteins c-ets - metabolism; Transcription Factors - metabolism; Tuberculosis - microbiology; Tuberculosis - mortality