Type III secretion chaperones of Pseudomonas syringae protect effectors from Lon‐associated degradation

• Published in: Molecular microbiology Vol. 55; no. 3; pp. 941 - 953
• Main Authors: Losada, Liliana C., Hutcheson, Steven W.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.02.2005; Blackwell Science; Blackwell Publishing Ltd
• Subjects: Bacteria; Bacterial Proteins - chemistry; Bacterial Proteins - metabolism; Bacteriology; Biological and medical sciences; DNA-Binding Proteins - metabolism; Escherichia coli - genetics; Escherichia coli - metabolism; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation, Bacterial; Microbiology; Miscellaneous; Molecular Chaperones - metabolism; Nicotiana - microbiology; Pathogens; Plant Diseases - microbiology; Plant Leaves - microbiology; Protease La - metabolism; Proteins; Pseudomonas syringae; Pseudomonas syringae - genetics; Pseudomonas syringae - metabolism; Pseudomonas syringae - pathogenicity; Sigma Factor - metabolism; Pseudomonadales; Microbiology; Pseudomonas syringae; Secretion; Chaperone; Bacteria; Pseudomonadaceae; Protein

Summary The hrp type III secretion system (TTSS) of Pseudomonas syringae translocates effector proteins into the cytoplasm of host cells. Proteolysis of HrpR by Lon has been shown to negatively regulate the hrp TTSS. The inability to bypass Lon‐associated effects on the regulatory system by ectopic...