The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins - Flanders, James A; Feng, Qiyu; Bagrodia, Shubha; Laux, Maria T; Singavarapu, Avinash; Cerione, Richard A (FEBS Letters, 2003)
Keywords: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Binding, Competitive; Breast cancer cell; Breast Neoplasms; Breast Neoplasms - metabolism; Carrier Proteins; Carrier Proteins - genetics; Carrier Proteins - metabolism; Cbl; Cbl, Casitas B-lymphoma; Cdc42; Cell Cycle Proteins; Cell Cycle Proteins - genetics; Cell Cycle Proteins - metabolism; Cool, cloned out of library; COS Cells; Female; Guanine Nucleotide Exchange Factors; Guanine Nucleotide Exchange Factors - genetics; Guanine Nucleotide Exchange Factors - metabolism; Humans; Molecular Sequence Data; p21-activated kinase; p21-Activated Kinases; PAK, p21-activated kinase; Phosphoproteins; Phosphoproteins - genetics; Phosphoproteins - metabolism; Pix, PAK-interactive exchange factor; Protein Binding; Protein Serine-Threonine Kinases; Protein-Serine-Threonine Kinases - genetics; Protein-Serine-Threonine Kinases - metabolism; Proto-Oncogene Proteins; Proto-Oncogene Proteins - genetics; Proto-Oncogene Proteins - metabolism; Proto-Oncogene Proteins c-cbl; Rho Guanine Nucleotide Exchange Factors; SH3 domain; src Homology Domains; src Homology Domains - physiology; Tumor Cells, Cultured; Two-Hybrid System Techniques; Ubiquitin-Protein Ligases; SH3 domain; PAK, p21-activated kinase; p21-activated kinase; Cbl, Casitas B-lymphoma; Breast cancer cell; Cbl; Pix, PAK-interactive exchange factor; Cool, cloned out of library; Cdc42