Amygdalar Metabolic Activity Independently Associates With Progression of Visceral Adiposity

• Published in: The journal of clinical endocrinology and metabolism Vol. 104; no. 4; pp. 1029 - 1038
• Main Authors: Ishai, Amorina, Osborne, Michael T, Tung, Brian, Wang, Ying, Hammad, Basma, Patrich, Tomas, Oberfeld, Blake, Fayad, Zahi A, Giles, Jon T, Lo, Janet, Shin, Lisa M, Grinspoon, Steven K, Koenen, Karestan C, Pitman, Roger K, Tawakol, Ahmed
• Format: Journal Article
• Language: English
• Published: Washington, DC Endocrine Society 01.04.2019; Copyright Oxford University Press; Oxford University Press
• Subjects: Adipose tissue; Adipose tissues; Adiposity - physiology; Adult; Aged; Amygdala; Amygdala - diagnostic imaging; Amygdala - metabolism; Amygdala - physiopathology; Body mass index; Bone marrow; Bone Marrow - metabolism; Clinical s; Computed tomography; Development and progression; Epidemiology; Female; Fluorodeoxyglucose F18 - administration & dosage; Follow-Up Studies; Humans; Inflammatory diseases; Intra-Abdominal Fat - diagnostic imaging; Male; Mediation; Metabolism; Middle Aged; Obesity, Abdominal - diagnostic imaging; Obesity, Abdominal - etiology; Obesity, Abdominal - physiopathology; Patients; Positron emission tomography; Positron Emission Tomography Computed Tomography; Retrospective Studies; Social interactions; Stress (Psychology); Stress, Psychological - complications; Stress, Psychological - physiopathology; Tomography; Massachusetts; United States > US

Abstract Context Epidemiologic data link psychological stress to adiposity. The underlying mechanisms remain uncertain. Objectives To test whether (i) higher activity of the amygdala, a neural center involved in the response to stress, associates with greater visceral adipose tissue (VAT) volumes an...