Hypoxia and Placental Development
Hemochorial placentation is orchestrated through highly regulated temporal and spatial decisions governing the fate of trophoblast stem/progenitor cells. Trophoblast cell acquisition of specializations facilitating invasion and uterine spiral artery remodeling is a labile process, sensitive to the e...
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| Published in | Birth defects research Vol. 109; no. 17; p. 1309 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
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16.10.2017
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| Abstract | Hemochorial placentation is orchestrated through highly regulated temporal and spatial decisions governing the fate of trophoblast stem/progenitor cells. Trophoblast cell acquisition of specializations facilitating invasion and uterine spiral artery remodeling is a labile process, sensitive to the environment, and represents a process that is vulnerable to dysmorphogenesis in pathologic states. Hypoxia is a signal guiding placental development, and molecular mechanisms directing cellular adaptations to low oxygen tension are integral to trophoblast cell differentiation and placentation. Hypoxia can also be used as an experimental tool to investigate regulatory processes controlling hemochorial placentation. These developmental processes are conserved in mouse, rat, and human placentation. Consequently, elements of these developmental events can be modeled and hypotheses tested in trophoblast stem cells and in genetically manipulated rodents. Hypoxia is also a consequence of a failed placenta, yielding pathologies that can adversely affect maternal adjustments to pregnancy, fetal health, and susceptibility to adult disease. The capacity of the placenta for adaptation to environmental challenges highlights the importance of its plasticity in safeguarding a healthy pregnancy. Birth Defects Research 109:1309-1329, 2017.© 2017 Wiley Periodicals, Inc. |
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| AbstractList | Hemochorial placentation is orchestrated through highly regulated temporal and spatial decisions governing the fate of trophoblast stem/progenitor cells. Trophoblast cell acquisition of specializations facilitating invasion and uterine spiral artery remodeling is a labile process, sensitive to the environment, and represents a process that is vulnerable to dysmorphogenesis in pathologic states. Hypoxia is a signal guiding placental development, and molecular mechanisms directing cellular adaptations to low oxygen tension are integral to trophoblast cell differentiation and placentation. Hypoxia can also be used as an experimental tool to investigate regulatory processes controlling hemochorial placentation. These developmental processes are conserved in mouse, rat, and human placentation. Consequently, elements of these developmental events can be modeled and hypotheses tested in trophoblast stem cells and in genetically manipulated rodents. Hypoxia is also a consequence of a failed placenta, yielding pathologies that can adversely affect maternal adjustments to pregnancy, fetal health, and susceptibility to adult disease. The capacity of the placenta for adaptation to environmental challenges highlights the importance of its plasticity in safeguarding a healthy pregnancy. Birth Defects Research 109:1309-1329, 2017.© 2017 Wiley Periodicals, Inc. |
| Author | Kozai, Keisuke Iqbal, Khursheed Soares, Michael J |
| Author_xml | – sequence: 1 givenname: Michael J surname: Soares fullname: Soares, Michael J organization: Fetal Health Research, Children's Research Institute, Children's Mercy, Kansas City, Missouri – sequence: 2 givenname: Khursheed surname: Iqbal fullname: Iqbal, Khursheed organization: Institute for Reproduction and Perinatal Research, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas – sequence: 3 givenname: Keisuke surname: Kozai fullname: Kozai, Keisuke organization: Institute for Reproduction and Perinatal Research, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29105383$$D View this record in MEDLINE/PubMed |
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| References | 24272361 - Adv Exp Med Biol. 2014;772:205-27 23150513 - Hypertension. 2013 Jan;61(1):259-66 10465273 - Endocrinology. 1999 Sep;140(9):4032-9 15033310 - Placenta. 2004 Apr;25 Suppl A:S60-71 10712429 - J Clin Invest. 2000 Mar;105(5):577-87 19923363 - Am J Physiol Regul Integr Comp Physiol. 2010 Feb;298(2):R312-9 25926690 - Reproduction. 2015 Jun;149(6):625-32 22523250 - Am J Physiol Heart Circ Physiol. 2012 Jul;303(1):H1-8 18469803 - Nature. 2008 Jun 19;453(7198):1117-21 21098220 - J Immunol. 2011 Jan 1;186(1):539-48 3047555 - Mol Endocrinol. 1988 Jun;2(6):579-86 12657505 - Placenta. 2003 Apr;24(4):326-35 17525282 - Am J Pathol. 2007 Jun;170(6):2171-9 12080413 - Microcirculation. 2002 Jul;9(3):147-60 20059947 - Dev Cell. 2009 Dec;17 (6):755-73 10329872 - Am J Obstet Gynecol. 1999 May;180(5):1161-8 8371099 - J Exp Zool. 1993 Sep 1;266(6):578-87 15823618 - Placenta. 2005 Apr;26(4):319-28 10486489 - Am J Obstet Gynecol. 1999 Sep;181(3):718-24 10409714 - J Biol Chem. 1999 Jul 23;274(30):21485-9 28673571 - Med Hypotheses. 2017 Jul;104:128-132 12488360 - Endocrinology. 2003 Jan;144(1):313-25 22659845 - Cell Cycle. 2012 Jul 1;11(13):2427-30 17324580 - Trends Endocrinol Metab. 2007 Apr;18(3):114-21 9573461 - Biol Neonate. 1998;73(5):313-9 24424031 - Endocrinology. 2014 Mar;155(3):1099-106 16481593 - Biol Reprod. 2006 Jun;74(6):1041-50 20646932 - Trends Endocrinol Metab. 2010 Sep;21(9):529-36 16195457 - Science. 2005 Sep 30;309(5744):2202-4 16579983 - Dev Biol. 2006 Jun 1;294(1):67-82 22562152 - EMBO J. 2012 May 30;31(11):2448-60 15236651 - Reprod Biol Endocrinol. 2004 Jul 05;2:51 15333578 - FASEB J. 2004 Sep;18(12 ):1348-65 22552791 - Am J Physiol Regul Integr Comp Physiol. 2012 Jul 1;303(1):R86-93 11902584 - Nat Rev Cancer. 2002 Jan;2(1):38-47 12426580 - Nat Biotechnol. 2002 Dec;20(12):1261-4 8940384 - Endocrinology. 1996 Dec;137(12):5558-66 8707870 - J Cell Physiol. 1996 Aug;168(2):346-53 24103835 - Blood Cells Mol Dis. 2013 Dec;51(4):256-63 16129025 - BMC Genomics. 2005 Aug 29;6:111 9887100 - Genes Dev. 1999 Jan 1;13(1):64-75 26362531 - Curr Hypertens Rep. 2015 Nov;17(11):83 21094932 - Am J Obstet Gynecol. 2011 Mar;204(3):193-201 17706280 - Placenta. 2007 Nov-Dec;28(11-12):1141-6 19497979 - Endocrinology. 2009 Sep;150(9):4306-15 26171964 - PLoS One. 2015 Jul 14;10(7):e0132468 14597660 - Genes Dev. 2003 Nov 1;17 (21):2614-23 20580083 - Placenta. 2010 Aug;31(8):731-7 11978059 - Placenta. 2002 Apr;23 Suppl A:S47-57 16611863 - Biol Reprod. 2006 Jul;75(1):112-21 27806942 - Biol Reprod. 2016 Dec;95(6):128 9472921 - Biol Reprod. 1998 Jan;58(1):45-51 10906065 - Biol Reprod. 2000 Aug;63(2):559-69 26862703 - Stem Cell Reports. 2016 Feb 9;6(2):257-72 24395887 - J Exp Med. 2014 Jan 13;211(1):165-79 15689487 - Mol Biol Cell. 2005 Apr;16(4):1901-12 20711986 - Int J Dev Biol. 2010;54(6-7):1089-98 10328919 - Dev Biol. 1999 May 15;209(2):254-67 16251750 - Methods Mol Med. 2006;121:295-313 24084523 - Reprod Sci. 2014 Apr;21(4):492-502 17166917 - Development. 2007 Jan;134(2):407-15 16897344 - Mamm Genome. 2006 Aug;17(8):858-77 15737933 - Dev Cell. 2005 Mar;8(3):377-87 25443433 - Placenta. 2014 Dec;35(12):1079-88 12778114 - Nat Struct Biol. 2003 Jul;10(7):504-12 7526325 - Pediatr Res. 1994 Aug;36(2):152-8 19175804 - J Anat. 2009 Jul;215(1):27-35 12917334 - Mol Cell Biol. 2003 Sep;23(17):6117-28 23437279 - PLoS One. 2013;8(2):e56949 18310520 - Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1638-44 24141110 - Stem Cell Res. 2014 Jan;12(1):24-35 10342862 - Endocrinology. 1999 Jun;140(6):2711-20 26377136 - J Physiol. 2016 Mar 1;594(5):1341-56 25239494 - Stem Cell Res. 2014 Nov;13(3 Pt A):478-91 27325764 - Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3882-91 20711229 - Cell Mol Immunol. 2011 Jan;8(1):1-11 17095594 - Endocrinology. 2007 Feb;148(2):559-65 18371450 - Cell Stem Cell. 2008 Mar 6;2(3):252-63 9436976 - Genes Dev. 1998 Jan 15;12(2):149-62 24518070 - Reproduction. 2014 Apr 10;147(5):D1-12 26778584 - Bioessays. 2016 Mar;38(3):254-65 21801864 - Am J Pathol. 2011 Aug;179(2):590-602 19796619 - Cell Stem Cell. 2009 Oct 2;5(4):385-95 24803182 - Dev Biol. 2014 Aug 1;392(1):62-79 17371845 - Mol Cell Biol. 2007 Jun;27(11):4142-56 11303211 - Am J Obstet Gynecol. 2001 Apr;184(5):998-1003 21555345 - J Endocrinol. 2011 Sep;210(3):243-58 3359962 - Endocrinology. 1988 May;122(5):1761-8 27118838 - Proc Natl Acad Sci U S A. 2016 May 10;113(19):5144-6 18498744 - Mol Cell. 2008 May 23;30(4):393-402 11018749 - J Endocrinol. 2000 Oct;167(1):15-28 19215320 - J Anat. 2009 Jul;215(1):14-20 12717822 - Bioessays. 2003 May;25(5):515-9 25023691 - Int J Dev Biol. 2014;58(2-4):247-59 15364904 - Genome Res. 2004 Oct;14(10A):1888-901 17636235 - Reprod Sci. 2007 Apr;14(3):223-33 20836033 - Wiley Interdiscip Rev Syst Biol Med. 2010 May-Jun;2(3):336-61 22615111 - Hypertension. 2012 Jul;60(1):231-8 7723678 - Metabolism. 1995 Apr;44(4):532-7 20967267 - PLoS One. 2010 Oct 12;5(10):e13288 23555853 - PLoS One. 2013;8(3):e59971 7010344 - Placenta. 1981 Jan-Mar;2(1):71-91 9256442 - Proc Natl Acad Sci U S A. 1997 Aug 19;94(17 ):9102-7 28423052 - PLoS One. 2017 Apr 19;12 (4):e0175805 25968580 - Am J Physiol Endocrinol Metab. 2015 Jul 1;309(1):E84-94 7527157 - Science. 1994 Dec 2;266(5190):1581-4 19439352 - Placenta. 2009 Jun;30(6):523-8 12620937 - Biol Reprod. 2003 Jul;69(1):1-7 12566246 - Placenta. 2003 Feb-Mar;24(2-3):191-8 25505199 - Biol Reprod. 2015 Feb;92 (2):36 22427062 - Cell Tissue Res. 2012 Sep;349(3):809-24 20163400 - Am J Reprod Immunol. 2010 Jun;63(6):482-91 16195499 - Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R844-51 23767827 - Stem Cells Dev. 2013 Nov 1;22(21):2815-24 16009940 - Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10200-5 20965423 - Mol Cell. 2010 Oct 22;40(2):294-309 22284666 - Placenta. 2012 Apr;33(4):233-43 19802386 - PLoS One. 2009 Oct 05;4(10 ):e7332 9606183 - EMBO J. 1998 Jun 1;17(11):3005-15 15963972 - Dev Biol. 2005 Aug 1;284(1):12-24 19757391 - Int J Dev Biol. 2010;54(2-3):303-12 8107053 - J Reprod Fertil. 1993 Nov;99(2):673-9 21187445 - J Immunol. 2011 Feb 1;186(3):1799-808 20660062 - Endocrinology. 2010 Sep;151(9):4537-50 11869088 - Placenta. 2002 Jan;23(1):3-19 8090202 - Nature. 1994 Sep 22;371(6495):333-6 8567979 - J Clin Invest. 1996 Jan 15;97(2):540-50 18616428 - Annu Rev Cell Dev Biol. 2008;24:159-81 27940158 - Dev Biol. 2017 Feb 15;422(2):171-185 21742476 - Exp Toxicol Pathol. 2013 Jan;65(1-2):97-103 21536153 - Respir Physiol Neurobiol. 2011 Aug 31;178(1):181-90 9047009 - Biol Reprod. 1997 Mar;56(3):647-54 8710813 - Placenta. 1996 Jan;17 (1):49-55 22623621 - Biol Reprod. 2012 Aug 23;87(2):37 27683262 - Biol Reprod. 2016 Nov;95(5):110 9121557 - Nature. 1997 Mar 27;386(6623):403-7 11124810 - Genes Dev. 2000 Dec 15;14(24):3191-203 15737932 - Dev Cell. 2005 Mar;8(3):365-75 10940194 - Placenta. 2000 Jul-Aug;21(5-6):443-50 10685059 - J Pathol. 2000 Feb;190(3):244-54 11169851 - Dev Dyn. 2001 Feb;220(2):175-86 3420324 - Respir Physiol. 1988 Aug;73(2):225-41 25519187 - Biol Reprod. 2015 Feb;92 (2):48 3251898 - Int J Rad Appl Instrum B. 1988;15(6):645-50 11043580 - Mol Endocrinol. 2000 Oct;14(10):1661-73 12885563 - Dev Biol. 2003 Aug 1;260(1):176-90 20458141 - J Clin Invest. 2010 Jun;120(6):2119-30 19683511 - Biochem Biophys Res Commun. 2009 Dec 18;390(3):372-6 27501156 - Curr Opin Genet Dev. 2016 Dec;41:8-13 21900602 - Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16295-300 16234296 - Hum Reprod Update. 2006 Mar-Apr;12(2):137-44 9287221 - Science. 1997 Sep 12;277(5332):1669-72 28273070 - Nature. 2017 Mar 16;543(7645):447-451 18815358 - Biol Reprod. 2009 Jan;80(1):184-93 21511332 - Placenta. 2011 Jun;32(6):475-81 19375795 - Placenta. 2009 Jun;30(6):473-82 17202390 - Biol Reprod. 2007 Apr;76(4):709-18 24201705 - J Appl Physiol (1985). 2014 Apr 1;116(7):875-84 11084652 - Dev Dyn. 2000 Dec;219(4):526-38 9165040 - Endocrinology. 1997 Jun;138(6):2491-500 21216006 - Placenta. 2011 Mar;32 Suppl 2:S109-18 7925104 - Endocrinology. 1994 Oct;135(4):1422-7 22387002 - Dev Cell. 2012 Mar 13;22(3):651-9 15353580 - Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14300-4 1954876 - Endocrinology. 1991 Dec;129(6):2895-906 11575145 - Gynecol Obstet Fertil. 2001 Jul-Aug;29(7-8):503-8 23314690 - Epigenetics. 2013 Feb;8(2):192-202 26278110 - J Physiol. 2016 Mar 1;594(5):1371-88 26504231 - Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6175-84 15132953 - Am J Physiol Lung Cell Mol Physiol. 2004 Sep;287(3):L525-32 11694877 - Nat Genet. 2001 Dec;29(4):469-74 24668059 - Mamm Genome. 2014 Jun;25(5-6):253-61 18199431 - Dev Biol. 2008 Feb 15;314(2):362-75 12855050 - High Alt Med Biol. 2003 Summer;4(2):171-91 10203658 - Am J Obstet Gynecol. 1999 Apr;180(4):896-902 26110512 - J Physiol. 2016 Mar 1;594(5):1357-69 20628147 - Blood. 2010 Oct 28;116(17):3321-30 8829210 - Placenta. 1996 Jul-Aug;17(5-6):277-89 16567961 - Curr Opin Hematol. 2006 May;13(3):169-74 9851926 - Science. 1998 Dec 11;282(5396):2072-5 9389541 - Endocrinology. 1997 Dec;138(12):5535-40 20399150 - Cell Metab. 2010 May 5;11(5):364-78 17658597 - Placenta. 2007 Nov-Dec;28(11-12):1147-57 15545614 - Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16543-8 28067578 - Hypertens Pregnancy. 2017 May;36(2):145-150 11013351 - J Mol Endocrinol. 2000 Oct;25(2):253-62 12376109 - Dev Biol. 2002 Oct 15;250(2):358-73 26660559 - Physiol Rep. 2015 Dec;3(12):null 19208786 - Reprod Sci. 2009 Feb;16(2):178-87 12744931 - Placenta. 2003 May;24(5):540-8 26985002 - Biol Reprod. 2016 May;94(5):107 16966370 - Mol Cell Biol. 2006 Nov;26(22):8336-46 1149717 - Environ Physiol Biochem. 1975;5(2):65-72 3512258 - Endocrinology. 1986 Apr;118(4):1567-82 14656203 - J Endocrinol. 2003 Dec;179(3):335-46 9389538 - Endocrinology. 1997 Dec;138(12):5511-7 23817493 - Hypertension. 2013 Sep;62(3):599-607 19161426 - Immunol Rev. 2008 Dec;226:205-18 9389542 - Endocrinology. 1997 Dec;138(12):5541-9 2667962 - Endocrinology. 1989 Sep;125(3):1565-74 19075097 - Hypertension. 2009 Feb;53(2):399-403 15987772 - Development. 2005 Aug;132(15):3393-403 3697431 - Biol Neonate. 1986;49(2):85-9 25307528 - Am J Pathol. 2014 Dec;184(12):3321-31 12398815 - Placenta. 2002 Nov;23 (10 ):751-62 1635745 - Obstet Gynecol. 1992 Aug;80(2):283-5 28395334 - Biol Reprod. 20 |
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