Innate immunity of the sinonasal cavity and its role in chronic rhinosinusitis

• Published in: Otolaryngology-head and neck surgery Vol. 136; no. 3; p. 348
• Main Authors: Ramanathan, Jr, Murugappan, Lane, Andrew P
• Format: Journal Article
• Language: English
• Published: England 01.03.2007
• Subjects: Chronic Disease; Humans; Immunity, Innate - immunology; Immunity, Mucosal - immunology; Nasal Cavity - immunology; Paranasal Sinuses - immunology; Rhinitis - immunology; Sinusitis - immunology; Toll-Like Receptors - agonists; Toll-Like Receptors - immunology

Chronic rhinosinusitis (CRS) is one of the most common health problems in the United States. Medical therapy and surgery are successful in treating the majority of patients with sinusitis; however, CRS patients recalcitrant to traditional therapy are increasingly prevalent. Although traditionally th...