Association of slow recovery of Mycobacterium africanum-infected patients posttreatment with high content of Persister-Like bacilli in pretreatment sputum

• Published in: International journal of mycobacteriology Vol. 5; no. 5; pp. S99 - S100
• Main Authors: Tientcheu, Leopold D., Bell, Andrew, Secka, Oumie, Ayorinde, Abigail, Otu, Jacob, Garton, Nathalie J., Sutherland, Jayne S., Ota, Martin O., Antonio, Martin, Dockrell, H.M., Kampmann, Beate, Barer, Michael R.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.12.2016; Medknow Publications and Media Pvt. Ltd; Wolters Kluwer Medknow Publications
• Subjects: Drug tolerance; Lipid body; Mycobacterium africanum; Tuberculosis; Tuberculosis treatment; Lipid body; Drug tolerance; Tuberculosis treatment; Mycobacterium africanum

Mycobacterium africanum that causes 40% of tuberculosis (TB) in West Africa grows more slowly in culture and has similar transmission capacity compared with Mycobacterium tuberculosis, but M. africanum-exposed contacts progress more slowly to active disease. The presence of lipid body (LB) containin...