Helminthosporic acid functions as an agonist for gibberellin receptor

• Published in: Bioscience, biotechnology, and biochemistry Vol. 81; no. 11; pp. 2152 - 2159
• Main Authors: Miyazaki, Sho, Jiang, Kai, Kobayashi, Masatomo, Asami, Tadao, Nakajima, Masatoshi
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 02.11.2017; Oxford University Press
• Subjects: Arabidopsis - metabolism; Bridged-Ring Compounds - metabolism; Bridged-Ring Compounds - pharmacology; GA-like; gibberellin; Gibberellins - metabolism; helminthosporic acid; helminthosporol; Molecular Docking Simulation; natural product; Oryza - metabolism; Plant Proteins - agonists; Plant Proteins - chemistry; Plant Proteins - metabolism; Protein Conformation; Receptors, Cell Surface - agonists; Receptors, Cell Surface - chemistry; Receptors, Cell Surface - metabolism; helminthosporol; GA-like; helminthosporic acid; gibberellin; natural product

Helminthosporol was isolated from a fungus, Helminthosporium sativum, as a natural plant growth regulator in 1963. It showed gibberellin-like bioactivity that stimulated the growth of the second leaf sheath of rice. After studying the structure-activity relationship between the compound and some syn...