Transcatheter Aortic Valve Replacement Using a Self-Expanding Bioprosthesis in Patients With Severe Aortic Stenosis at Extreme Risk for Surgery

• Published in: Journal of the American College of Cardiology Vol. 63; no. 19; pp. 1972 - 1981
• Main Authors: Popma, Jeffrey J., Adams, David H., Reardon, Michael J., Yakubov, Steven J., Kleiman, Neal S., Heimansohn, David, Hermiller, James, Hughes, G. Chad, Harrison, J. Kevin, Coselli, Joseph, Diez, Jose, Kafi, Ali, Schreiber, Theodore, Gleason, Thomas G., Conte, John, Buchbinder, Maurice, Deeb, G. Michael, Carabello, Blasé, Serruys, Patrick W., Chenoweth, Sharla, Oh, Jae K.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 20.05.2014; Elsevier; Elsevier Limited
• Subjects: Aged; Aged, 80 and over; aortic stenosis; Aortic Valve Stenosis - diagnosis; Aortic Valve Stenosis - surgery; Aspirin; Biological and medical sciences; Bioprosthesis - standards; Cardiac Catheterization - instrumentation; Cardiac Catheterization - methods; Cardiology; Cardiology. Vascular system; Cardiovascular; Catheters; Female; Follow-Up Studies; Heart; Heart Valve Prosthesis - standards; Heart Valve Prosthesis Implantation - instrumentation; Heart Valve Prosthesis Implantation - methods; Humans; Male; Medical imaging; Medical prognosis; Medical sciences; Mortality; outcomes; Patients; Prospective Studies; Prosthesis Design - standards; Risk Factors; Severity of Illness Index; Stroke; Surgery; transcatheter aortic valve replacement; Treatment Outcome; NYHA; aortic stenosis; THV; VARC; outcomes; STS-PROM; OPG; transcatheter aortic valve replacement; EuroSCORE; MACCE; SAVR; TAVR; European System for Cardiac Operative Risk Evaluation; objective performance goal; transcatheter heart valve; Valve Academic Research Consortium; major adverse cardiovascular and cerebral event(s); New York Heart Association; Society for Thoracic Surgery Predicted Risk of Mortality; surgical aortic valve replacement; Human; Aortic stenosis; Prosthesis; Bioprosthesis; Patient; Cardiovascular disease; Self; Heart valve; Treatment; Expanding; Surgery; Circulatory system; Cardiology; Severe; Aortic valve

This study sought to evaluate the safety and efficacy of the CoreValve transcatheter heart valve (THV) for the treatment of severe aortic stenosis in patients at extreme risk for surgery. Untreated severe aortic stenosis is a progressive disease with a poor prognosis. Transcatheter aortic valve repl...