Neuroplasticity — Exercise-Induced Response of Peripheral Brain-Derived Neurotrophic Factor A Systematic Review of Experimental Studies in Human Subjects

• Published in: Sports medicine (Auckland) Vol. 40; no. 9; pp. 765 - 801
• Main Authors: Knaepen, Kristel, Goekint, Maaike, Heyman, Elsa Marie, Meeusen, Romain
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.09.2010; Adis International; Wolters Kluwer Health, Inc; Springer Nature B.V
• Subjects: Biological and medical sciences; Brain-Derived Neurotrophic Factor - blood; Brain-Derived Neurotrophic Factor - physiology; Central nervous system; Central neurotransmission. Neuromudulation. Pathways and receptors; Chronic Disease; Exercise; Exercise - physiology; Fundamental and applied biological sciences. Psychology; Health aspects; Humans; Medicine; Medicine & Public Health; Neuronal Plasticity - physiology; Neuroplasticity; Neurotrophic functions; Persons with Disabilities - rehabilitation; Physical Education and Training; Physiological aspects; Research Review Article; Sports Medicine; Vertebrates: nervous system and sense organs; United States; Spinal Cord Injure; Aerobic Training; Acute Exercise; Trained Subject; Strength Training; Physical exercise; Human; Neurotrophin; Central nervous system; Plasticity; Review; Brain derived neurotrophic factor; Experimental study; Encephalon
• ISSN: 0112-1642; 1179-2035; 1179-2035
• DOI: 10.2165/11534530-000000000-00000

Exercise is known to induce a cascade of molecular and cellular processes that support brain plasticity. Brain-derived neurotrophic factor (BDNF) is an essential neurotrophin that is also intimately connected with central and peripheral molecular processes of energy metabolism and homeostasis, and c...