Validation and Estimation of Obesity-Induced Intervertebral Disc Degeneration through Subject-Specific Finite Element Modelling of Functional Spinal Units

• Published in: Bioengineering (Basel) Vol. 11; no. 4; p. 344
• Main Authors: Singh, Nitesh Kumar, Singh, Nishant K., Verma, Rati, Diwan, Ashish D.
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.04.2024
• Subjects: Analysis; Axial stress; Back pain; Backache; Bending; Biomechanics; Body mass index; Body size; Body weight; Care and treatment; Complications and side effects; Computer simulation; Deformation; Degeneration; Degenerative disc disease; Diagnosis; finite element analysis; Finite element method; Health aspects; Hernia; intervertebral disc; Intervertebral discs; Intervertebral disk; Intervertebral disk displacement; Ligaments; Low back pain; lumbar spine; Mathematical models; Obesity; Overweight; Rotation; Spine; Three dimensional models; Vertebrae; Weight control; India; lumbar spine; intervertebral disc; finite element analysis; body mass index; degeneration; obesity

(1) Background: Intervertebral disc degeneration has been linked to obesity; its potential mechanical effects on the intervertebral disc remain unknown. This study aimed to develop and validate a patient-specific model of L3–L4 vertebrae and then use the model to estimate the impact of increasing bo...