Right Ventricular End-Diastolic Volume Combined With Peak Systolic Blood Pressure During Exercise Identifies Patients at Risk for Complications in Adults With a Systemic Right Ventricle

• Published in: Journal of the American College of Cardiology Vol. 62; no. 10; pp. 926 - 936
• Main Authors: van der Bom, Teun, Winter, Michiel M., Groenink, Maarten, Vliegen, Hubert W., Pieper, Petronella G., van Dijk, Arie P.J., Sieswerda, Gertjan T., Roos-Hesselink, Jolien W., Zwinderman, Aeilko H., Mulder, Barbara J.M., Bouma, Berto J.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 03.09.2013; Elsevier; Elsevier Limited
• Subjects: Adult; Arrhythmias, Cardiac - complications; Arrhythmias, Cardiac - epidemiology; Arrhythmias, Cardiac - etiology; Biological and medical sciences; Blood Pressure - physiology; Cardiac arrhythmia; Cardiology; Cardiology. Vascular system; Cardiovascular; clinical events; Drug therapy; Echocardiography; Electrocardiography; Exercise - physiology; Exercise Test; Female; Follow-Up Studies; Heart; Heart attacks; Heart Failure - complications; Heart Failure - epidemiology; Heart Failure - etiology; Humans; Magnetic Resonance Imaging; Male; Medical sciences; Multidetector Computed Tomography; Prognosis; Proportional Hazards Models; Risk Factors; Stroke Volume - physiology; Survival Analysis; systemic right ventricle; Transposition of Great Vessels - complications; Transposition of Great Vessels - diagnostic imaging; Transposition of Great Vessels - mortality; Tricuspid Valve Insufficiency - complications; Tricuspid Valve Insufficiency - epidemiology; Tricuspid Valve Insufficiency - etiology; Ventricular Dysfunction, Right - complications; Ventricular Dysfunction, Right - mortality; Ventricular Dysfunction, Right - physiopathology; NYHA; SBP; CPET; clinical events; ECG; CMR; HR; MDCT; prognosis; ccTGA; TGA; systemic right ventricle; RVEDVi; congenitally corrected transposition of the great arteries; transposition of the great arteries; cardiopulmonary exercise testing; systolic blood pressure; electrocardiography; cardiovascular magnetic resonance imaging; multidetector-row computed tomography; New York Heart Association; hazard ratio; right ventricular end-diastolic volume index; Physical exercise; Human; Systolic pressure; Right ventricle; Patient; Cardiovascular disease; Systemic; End diastolic volume; Adult; Complication; Exercise tolerance test; Arterial pressure; Peak; Blood pressure; Hemodynamics; Circulatory system; Disseminated; Cardiology

The aim of this study was to identify which patients with a systemic right ventricle are at risk for clinical events. In patients with congenitally or atrially corrected transposition of the great arteries, worsening of the systemic right ventricle is accompanied by clinical events such as clinical...