Evaluation of the Relationship between CD44 Expression and Gleason Grade among Prostate Adenocarcinoma and Benign Prostatic Hyperplasia: A Cross-Sectional Study

• Published in: Medical principles and practice Vol. 34; no. 3; pp. 271 - 280
• Main Authors: Kianparsa, Joben, Soltanipur, Masood, Jalali Nadoushan, Mohammadreza
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.06.2025; Karger Publishers
• Subjects: Adenocarcinoma - metabolism; Adenocarcinoma - pathology; Age; Aged; Biomarkers; Biomarkers, Tumor - metabolism; Cell growth; Cross-Sectional Studies; Fallopian tubes; Humans; Hyaluronan Receptors - metabolism; Hyperplasia; Male; Medical prognosis; Middle Aged; Neoplasm Grading; Pathology; Patients; Prostate cancer; Prostatic Hyperplasia - metabolism; Prostatic Hyperplasia - pathology; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; Regression analysis; Research Article; Statistical analysis; Variables; United States > US; Gleason score; Benign prostatic hyperplasia (BPH); Cluster of differentiation 44; Prostate adenocarcinoma (PAC); CD44

AbstractIntroduction: This study aimed to investigate the expression of cluster of differentiation 44 (CD44) in prostate adenocarcinoma (PAC) compared to benign prostatic hyperplasia (BPH) to address the need for biomarkers that can aid in grading classification and prognosis. Methods: In this cross...