Ethical Considerations of Patient-Funded Research for Multiple Sclerosis Therapeutics
Patient-funded research has started to emerge in multiple sclerosis studies, such as low-dose naltrexone and stem-cell therapy. While these represent greater opportunities for the physician, scientist, and patient, ethical concerns concerning protocol review, conflict of interests, and protection of...
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| Published in | Neurotherapeutics Vol. 14; no. 4; pp. 945 - 951 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
New York
Elsevier Inc
01.10.2017
Springer US Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1878-7479 1933-7213 1878-7479 |
| DOI | 10.1007/s13311-017-0560-9 |
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| Abstract | Patient-funded research has started to emerge in multiple sclerosis studies, such as low-dose naltrexone and stem-cell therapy. While these represent greater opportunities for the physician, scientist, and patient, ethical concerns concerning protocol review, conflict of interests, and protection of subjects are reviewed. |
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| AbstractList | Patient-funded research has started to emerge in multiple sclerosis studies, such as low-dose naltrexone and stem-cell therapy. While these represent greater opportunities for the physician, scientist, and patient, ethical concerns concerning protocol review, conflict of interests, and protection of subjects are reviewed. Patient-funded research has started to emerge in multiple sclerosis studies, such as low-dose naltrexone and stem-cell therapy. While these represent greater opportunities for the physician, scientist, and patient, ethical concerns concerning protocol review, conflict of interests, and protection of subjects are reviewed.Patient-funded research has started to emerge in multiple sclerosis studies, such as low-dose naltrexone and stem-cell therapy. While these represent greater opportunities for the physician, scientist, and patient, ethical concerns concerning protocol review, conflict of interests, and protection of subjects are reviewed. |
| Author | Nelson, Flavia Amezcua, Lilyana |
| Author_xml | – sequence: 1 givenname: Lilyana orcidid: 0000-0003-1542-7819 surname: Amezcua fullname: Amezcua, Lilyana email: lamezcua@usc.edu organization: Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA – sequence: 2 givenname: Flavia surname: Nelson fullname: Nelson, Flavia organization: Department of Neurology, McGovern Medical School, University of Texas, Houston, TX, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28779373$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1007_s13311_017_0576_1 crossref_primary_10_1016_j_intimp_2018_05_020 crossref_primary_10_33920_med_03_2010_06 crossref_primary_10_18699_SSMJ20210101 crossref_primary_10_1016_j_jemep_2020_100465 crossref_primary_10_1016_j_preteyeres_2019_100779 |
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| Copyright | 2017 The American Society for Experimental NeuroTherapeutics, Inc. The American Society for Experimental NeuroTherapeutics, Inc. 2017 Neurotherapeutics is a copyright of Springer, (2017). All Rights Reserved. |
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| Keywords | Ethics Multiple sclerosis Patient-funded research |
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publication-title: JAMA doi: 10.1001/jama.283.20.2701 – volume: 10 start-page: e0135997 year: 2015 ident: 10.1007/s13311-017-0560-9_bib28 article-title: Clinical research in vulnerable populations: variability and focus of institutional review boards' responses publication-title: PLOS ONE doi: 10.1371/journal.pone.0135997 – volume: 42 start-page: 475 year: 2014 ident: 10.1007/s13311-017-0560-9_bib9 article-title: Trust and transparency: patient perceptions of physicians' financial relationships with pharmaceutical companies publication-title: J Law Med Ethics doi: 10.1111/jlme.12169 – volume: 3 start-page: 250 year: 2014 ident: 10.1007/s13311-017-0560-9_bib16 article-title: Efficient generation of myelinating oligodendrocytes from primary progressive multiple sclerosis patients by induced pluripotent stem cells publication-title: Stem Cell Rep doi: 10.1016/j.stemcr.2014.06.012 – volume: 11 start-page: 635 year: 2005 ident: 10.1007/s13311-017-0560-9_bib34 article-title: Multiple sclerosis management for low-income minorities publication-title: Mult Scler doi: 10.1191/1352458505ms1215oa – volume: 18 start-page: 1476 year: 2016 ident: 10.1007/s13311-017-0560-9_bib15 article-title: Clinical safety of intrathecal administration of mesenchymal stromal cell-derived neural progenitors in multiple sclerosis publication-title: Cytotherapy doi: 10.1016/j.jcyt.2016.08.007 – volume: 10 start-page: e1001402 year: 2013 ident: 10.1007/s13311-017-0560-9_bib7 article-title: Adapting standards: ethical oversight of participant-led health research publication-title: PLOS Med doi: 10.1371/journal.pmed.1001402 – ident: 10.1007/s13311-017-0560-9_bib23 – volume: 17 start-page: 135 year: 2015 ident: 10.1007/s13311-017-0560-9_bib6 article-title: Patient-funded trials: Opportunity or liability? 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| SubjectTerms | Biomedical and Life Sciences Biomedicine Ethics Humans Medical ethics Multiple sclerosis Multiple Sclerosis - economics Multiple Sclerosis - therapy Naltrexone Neurobiology Neurology Neurosciences Neurosurgery Patient Participation Patient-funded research Review Reviews Stem cells Translational Research, Biomedical - economics Translational Research, Biomedical - ethics |
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| Title | Ethical Considerations of Patient-Funded Research for Multiple Sclerosis Therapeutics |
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