Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection - Ruzicka, W B; Zhubi, A; Veldic, M; Grayson, D R; Costa, E; Guidotti, A (Molecular psychiatry, 2007)
Keywords: Adult; Adult and adolescent clinical studies; Behavioral Sciences; Biological and medical sciences; Biological Psychology; Bipolar disorder; Brain; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases - genetics; DNA (Cytosine-5-)-Methyltransferases - metabolism; DNA methylation; DNA methyltransferase; DNMT1 protein; Epigenesis, Genetic - physiology; Epigenetics; Female; gamma-Aminobutyric Acid - metabolism; Gene expression; Glutamate Decarboxylase - metabolism; Glutamic acid; Humans; Hybridization; Interneurons; Isoenzymes - metabolism; Lasers; Male; Medical sciences; Medicine; Medicine & Public Health; Mental disorders; Microdissection - methods; Middle Aged; Neurons; Neurons - metabolism; Neurons - pathology; Neurosciences; original-article; Patients; Pharmacotherapy; Polymerase chain reaction; Prefrontal cortex; Prefrontal Cortex - pathology; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Pyramidal cells; Reelin protein; Reverse Transcriptase Polymerase Chain Reaction - methods; Reverse transcription; RNA, Messenger - biosynthesis; Schizophrenia; Schizophrenia - etiology; Schizophrenia - genetics; Schizophrenia - pathology; γ-Aminobutyric acid; United States--US; Chicago Illinois; reelin; laser-assisted microdissection; DNMT1; GAD; schizophrenia; epigenetics; Human; Central nervous system; Schizophrenia; Prefrontal cortex; GAD67; Encephalon; Psychosis; Reelin; Epigenesis; Gabaergic neuron