The evaluation of neural and vascular hyper-reactivity for sensitive skin

• Published in: Skin research and technology Vol. 22; no. 3; pp. 381 - 387
• Main Authors: Sun, L., Wang, X., Zhang, Y., Wang, T., Li, X., Ma, Y.
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.08.2016; John Wiley & Sons, Inc
• Subjects: Adolescent; Adult; Capsaicin - administration & dosage; Female; Genes; Genetic Predisposition to Disease - genetics; heighted reaction; Humans; Hyperalgesia - diagnosis; Hyperalgesia - physiopathology; Lactic Acid - administration & dosage; Male; Middle Aged; neural; Neurovascular Coupling - drug effects; Pain Perception - drug effects; Pathogenesis; Sensory System Agents - administration & dosage; Skin; Skin - drug effects; Skin - physiopathology; Skin Tests; SNPs of TRPV1; TRPV Cation Channels - genetics; vascular; Young Adult; SNPs of TRPV1; neural; heighted reaction; vascular

Background The impaired barrier function has been studied comprehensively but few about the heighted neural and vascular reaction for the pathogenesis of sensitive skin. Methods Lactic acid stinging test (LAST) was used to identify sensitive subjects in selection phase. In the subsequent test phase,...