Consumption of Hibiscus sabdariffa L. aqueous extract and its impact on systemic antioxidant potential in healthy subjects

• Published in: Journal of the science of food and agriculture Vol. 92; no. 10; pp. 2207 - 2218
• Main Authors: Frank, Thomas, Netzel, Gabriele, Kammerer, Dietmar R, Carle, Reinhold, Kler, Adolf, Kriesl, Erwin, Bitsch, Irmgard, Bitsch, Roland, Netzel, Michael
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 15.08.2012; Wiley; John Wiley and Sons, Limited
• Subjects: administered dose; Adult; anthocyanins; Anthocyanins - pharmacology; Anthocyanins - urine; antioxidant activity; antioxidant potential; Antioxidants; Antioxidants - metabolism; Antioxidants - pharmacology; Aqueous solutions; Area Under Curve; ascorbic acid; Ascorbic Acid - blood; Biological and medical sciences; Biomarkers; Biomarkers - metabolism; Biotransformation; blood; chemistry; drug effects; excretion; Extraction processes; Female; Flowers & plants; Food industries; Food science; Fundamental and applied biological sciences. Psychology; Glucuronides; Glucuronides - pharmacology; Glucuronides - urine; Health; Hibiscus; Hibiscus - chemistry; Hibiscus sabdariffa; Hibiscus sabdariffa L; Hippurates; Hippurates - urine; hippuric acid; Humans; Male; malondialdehyde; Malondialdehyde - urine; metabolism; Oxidative stress; Oxidative Stress - drug effects; pharmacology; Plant Extracts; Plant Extracts - pharmacology; polyphenols; Polyphenols - pharmacology; Polyphenols - urine; Reference Values; uric acid; Uric Acid - blood; urine; volunteers; Young Adult; Malvaceae; Human; antioxidant potential; polyphenols; Hippuric acid; Healthy subject; Extract; Antioxidant; Hibiscus; Polyphenol; Dicotyledones; Angiospermae; Hibiscus sabdariffa L; Spermatophyta; malondialdehyde; humans

BACKGROUND: To evaluate health benefits attributed to Hibiscus sabdariffa L. a randomized, open‐label, two‐way crossover study was undertaken to compare the impact of an aqueous H. sabdariffa L. extract (HSE) on the systemic antioxidant potential (AOP; assayed by ferric reducing antioxidant power (F...