Synaptic changes in the brain of subjects with schizophrenia

• Published in: International journal of developmental neuroscience Vol. 29; no. 3; pp. 305 - 309
• Main Authors: Faludi, Gábor, Mirnics, Károly
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.05.2011
• Subjects: Animals; Gene expression; Humans; Postmortem; Pruning; Schizophrenia; Schizophrenia - pathology; Schizophrenia - physiopathology; Synapse; Synapses - pathology; Synapses - physiology; Synapses - ultrastructure; Schizophrenia; Pruning; Synapse; Gene expression; Postmortem

► Synaptic disturbances are integral and important part of schizophrenia pathophysiology. ► Synaptic disturbances cannot be studied and understood as an independent disease. ► We propose a molecular sub-stratification of schizophrenia into “synaptic” “oligodendroglial”, “metabolic” and “inflammatory...