Cellular and molecular determinants of stroke-induced changes in subventricular zone cell migration

• Published in: Antioxidants & redox signaling Vol. 14; no. 10; p. 1877
• Main Authors: Young, Christopher C, Brooks, Keith J, Buchan, Alastair M, Szele, Francis G
• Format: Journal Article
• Language: English
• Published: United States 15.05.2011
• Subjects: Animals; Cell Movement - physiology; Cerebral Ventricles - cytology; Humans; Neurogenesis - physiology; Stroke - physiopathology

A remarkable aspect of adult neurogenesis is that the tight regulation of subventricular zone (SVZ) neuroblast migration is altered after ischemic stroke and newborn neurons emigrate towards the injury. This phenomenon is an essential component of endogenous repair and also serves to illuminate norm...