Isotope-labeling in situ derivatization and HS-SPME arrow GC–MS/MS for simultaneous determination of fatty acids and fatty acid methyl esters in aqueous matrices

• Published in: Analytical and bioanalytical chemistry Vol. 415; no. 26; pp. 6525 - 6536
• Main Authors: Tintrop, Lucie K., Lieske-Overgrand, Jana R., Wickneswaran, Kaliyani, Abis, Rukiyye, Brunstermann, Ruth, Jochmann, Maik A., Schmidt, Torsten C.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2023; Springer; Springer Nature B.V
• Subjects: Analysis; Analytical Chemistry; Biochemistry; Bioreactors; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Design of experiments; Detection limits; Deuteration; Esters; Extraction (Chemistry); Fatty acid methyl esters; Fatty acids; Food Science; Gas chromatography; Headspace; Isotope effect; Labeling; Laboratory Medicine; Mass spectrometry; Mass spectroscopy; Methods; Methyl groups; Monitoring/Environmental Analysis; Optimization; Research Paper; Solid phase methods; Solid phases; Surface water; Wastewater treatment; Wastewater treatment plants; Germany; GC–MS/MS; Water; Isotope-labeling esterification; SPME arrow; Fatty acids; Fatty acid methyl esters

Fatty acids (FAs) and fatty acid methyl esters (FAMEs) co-occur in many samples, and analysis of both substance classes is frequently of high interest. To this end, this study introduces the first method for simultaneous determination of FAs and FAMEs including fully automated solvent-free solid-pha...