On the Emergence of Candida auris: Climate Change, Azoles, Swamps, and Birds

• Published in: mBio Vol. 10; no. 4
• Main Authors: Casadevall, Arturo, Kontoyiannis, Dimitrios P., Robert, Vincent
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 23.07.2019
• Subjects: Animals; Antifungal Agents - pharmacology; Azoles - pharmacology; Birds - microbiology; Candida; Candida - drug effects; Candida - pathogenicity; Candidiasis - microbiology; Climate Change; Communicable Diseases, Emerging - microbiology; Drug Resistance, Multiple, Fungal; fungus; Host-Microbe Biology; Humans; Microbial Sensitivity Tests; Opinion/Hypothesis; Phylogeny; Temperature; fungus; Candida; climate change

The most enigmatic aspect of the rise of Candida auris as a human pathogen is that it emerged simultaneously on three continents, with each clade being genetically distinct. Although new pathogenic fungal species are described regularly, these are mostly species associated with single cases in indiv...