Depletion of dopamine in Parkinson's disease and relevant therapeutic options: A review of the literature

• Published in: AIMS neuroscience Vol. 10; no. 3; pp. 200 - 231
• Main Authors: Ramesh, Sairam, Arachchige, Arosh S. Perera Molligoda
• Format: Journal Article
• Language: English
• Published: AIMS Press 01.01.2023
• Subjects: alpha-synuclein; braak; comt inhibitors; deep brain stimulation; dopal neurotoxicity; dopamine; l-dopa; mao inhibitors; parkinson's disease; Review; therapies

Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects motor and cognition functions. The etiology of Parkinson's disease remains largely unknown, but genetic and environmental factors are believed to play a role. The neurotransmitter dopamine is implicated in re...