Trinucleotide repeat expansion of TATA-binding protein gene associated with Parkinson's disease: A Thai multicenter study

• Published in: Parkinsonism & related disorders Vol. 28; pp. 146 - 149
• Main Authors: Choubtum, Lulin, Witoonpanich, Pirada, Kulkantrakorn, Kongkiat, Hanchaiphiboolkul, Suchat, Pongpakdee, Sunsanee, Tiamkao, Somsak, Pulkes, Teeratorn
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.07.2016
• Subjects: Adult; Aged; Aged, 80 and over; Aging - genetics; Case-Control Studies; Female; Humans; Male; Middle Aged; Neurology; Parkinson Disease - genetics; Parkinson's disease; Spinocerebellar ataxia type 17; TATA box-binding protein gene; TATA-Box Binding Protein - genetics; TBP; Thailand; Trinucleotide repeat expansion; Trinucleotide Repeat Expansion - genetics; Spinocerebellar ataxia type 17; TBP; Parkinson's disease; Trinucleotide repeat expansion; TATA box-binding protein gene

Spinocerebellar ataxia type 17 (SCA17) is an inherited cerebellar degeneration associated with trinucleotide repeat expansions in the TATA-binding protein gene (TBP). Low-range expansions of TBP have recently been described in association with Parkinson's disease (PD). However, these low-range...