Mixed and membrane-separated culturing of synthetic cyanobacteria-yeast consortia reveals metabolic cross-talk mimicking natural cyanolichens

• Published in: Scientific reports Vol. 14; no. 1; pp. 25303 - 19
• Main Authors: Bohutskyi, Pavlo, Pomraning, Kyle R., Jenkins, Jackson P, Kim, Young-Mo, Poirier, Brenton C, Betenbaugh, Michael J, Magnuson, Jon K
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 25.10.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 631/326/2565; 631/326/2565/855; Alcohols; Amino acids; BASIC BIOLOGICAL SCIENCES; Bioreactors; Bioreactors - microbiology; Biotechnology; Carbon cycle; Carbon dioxide; Coculture Techniques - methods; Cross-feeding; Cyanobacteria - genetics; Cyanobacteria - metabolism; Environmental science; Germfree; Humanities and Social Sciences; Intermediates; Lichens; Lichens - metabolism; Lichens - microbiology; Membrane-separated bioreactor; Metabolic engineering; Metabolism; Metabolite exchange; Metabolites; Microbial activity; Microbial communities; Microbial community; Microbial Consortia; Microbial ecology; Microbial Interactions; Microbiomes; multidisciplinary; Nitrogen cycle; Phototroph-heterotroph co-culture; Rhodotorula - genetics; Rhodotorula - metabolism; Science; Science (multidisciplinary); Sugar; Synechococcus - genetics; Synechococcus - metabolism; Synthetic lichen; Tricarboxylic acid cycle; Yeast; Membrane-separated bioreactor; Synthetic lichen; Metabolite exchange; Phototroph-heterotroph co-culture; Cross-feeding; Microbial community

Metabolite exchange mediates crucial interactions in microbial communities, significantly impacting global carbon and nitrogen cycling. Understanding these chemically-mediated interactions is essential for elucidating natural community functions and developing engineered synthetic communities. This...