The specificity of vesicle traffic to the Golgi is encoded in the golgin coiled-coil proteins

• Published in: Science (American Association for the Advancement of Science) Vol. 346; no. 6209; p. 601
• Main Authors: Wong, Mie, Munro, Sean
• Format: Journal Article
• Language: English
• Published: Washington American Association for the Advancement of Science 31.10.2014; The American Association for the Advancement of Science
• Subjects: cell membranes; Cells; Eukaryotes; Fuses; Golgi apparatus; Lipids; Membranes; mitochondria; physiological transport; Proteins; Relocation; RESEARCH ARTICLE SUMMARY; Tethers; Traffic; Traffic engineering; Traffic flow; Transport; Vesicles

The inside of the cell contains a large variety of different membrane transport vesicles, each of which needs to find and fuse with its correct target destination. The detailed mechanism specifying which vesicle can fuse with which target membrane has been the subject of an enormous amount of resear...