The visualisation and quantification of human gastrointestinal fat distribution with MRI: a randomised study in healthy subjects

• Published in: British journal of nutrition Vol. 115; no. 5; pp. 903 - 912
• Main Authors: Liu, Dian, Parker, Helen L., Curcic, Jelena, Schwizer, Werner, Fried, Michael, Kozerke, Sebastian, Steingoetter, Andreas
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 14.03.2016
• Subjects: Body Mass Index; correlation; Correlation coefficient; creaming; Cross-Over Studies; Dietary Fats - administration & dosage; Dietary Fats - metabolism; Digestion; Digestive system; droplet size; Emulsions; experimental design; Female; functional foods; Functional foods & nutraceuticals; Gastric Emptying; Gastrointestinal Contents; gastrointestinal system; Gastrointestinal tract; Gastrointestinal Tract - metabolism; Healthy Volunteers; Humans; Innovative Techniques; least squares; Magnetic Resonance Imaging; Male; NMR; Nuclear magnetic resonance; Oils & fats; Reproducibility of Results; separation; Single-Blind Method; Studies; Young Adult; Lipid emulsions; MRI; Water–fat separation; Gastric physiology; Gastrointestinal function; Healthy subjects; Biophysics of fat digestion; IDEAL iterative decomposition with echo asymmetry and least squares estimation; FCV fat content volume; GI gastrointestinal; TCV total content volumes

We aimed to study the fate of fat during digestion. For this purpose, we validated and investigated the non-invasive quantification of gastric and duodenal fat emptying and emulsion processing (creaming and phase separation) using the MRI method iterative decomposition with echo asymmetry and least...