Long-term survival and quality of life of patients with prolonged postoperative intensive care unit stay: Unmasking an apparent success
Objective Our objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (>10 days) postoperative stay in the intensive care unit and were discharged from the hospital. Methods Among 3125 consecutive patients who underwent cardiac operations in a 5-year...
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Published in | Journal of thoracic and cardiovascular surgery Vol. 134; no. 2; pp. 465 - 469 |
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Main Authors | , , , , , , , |
Format | Journal Article Conference Proceeding |
Language | English |
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Philadelphia, PA
Mosby, Inc
01.08.2007
AATS/WTSA Elsevier |
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Abstract | Objective Our objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (>10 days) postoperative stay in the intensive care unit and were discharged from the hospital. Methods Among 3125 consecutive patients who underwent cardiac operations in a 5-year period, we prospectively identified 57 who faced a prolonged postoperative intensive care unit stay and were discharged alive from the hospital. Patients were enrolled in a prospective follow-up protocol and evaluated every 6 to 12 months both clinically and instrumentally. Results Mean intensive care unit stay was 34 ± 9 days (range 11–141 days). Follow-up was complete and mean follow-up time was 71 months. Overall survival was 12 (21%) of 57, and the majority of follow-up deaths were cardiac related. Of the surviving patients, only a small minority (4/12) regained full autonomy and returned to their previous lifestyle. Risk factors for prolonged intensive care unit stay were age, New York Heart Association/Canadian Cardiovascular Society class, hypertension, diabetes, low ejection fraction, aortic surgery, preoperative renal failure, nonelective surgery, prolonged cardiopulmonary bypass time, and perioperative use of aortic counterpulsator. Conclusions Patients who face a prolonged postoperative intensive care unit stay and who were discharged from the hospital have a very poor long-term outcome and even worse quality of life. These data lead to a consideration of the wisdom of using heroic treatment in patients who face a prolonged postoperative intensive care unit stay in view of the dismal clinical results and enormous use of hospital and human resources. |
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AbstractList | Our objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (>10 days) postoperative stay in the intensive care unit and were discharged from the hospital.
Among 3125 consecutive patients who underwent cardiac operations in a 5-year period, we prospectively identified 57 who faced a prolonged postoperative intensive care unit stay and were discharged alive from the hospital. Patients were enrolled in a prospective follow-up protocol and evaluated every 6 to 12 months both clinically and instrumentally.
Mean intensive care unit stay was 34 +/- 9 days (range 11-141 days). Follow-up was complete and mean follow-up time was 71 months. Overall survival was 12 (21%) of 57, and the majority of follow-up deaths were cardiac related. Of the surviving patients, only a small minority (4/12) regained full autonomy and returned to their previous lifestyle. Risk factors for prolonged intensive care unit stay were age, New York Heart Association/Canadian Cardiovascular Society class, hypertension, diabetes, low ejection fraction, aortic surgery, preoperative renal failure, nonelective surgery, prolonged cardiopulmonary bypass time, and perioperative use of aortic counterpulsator.
Patients who face a prolonged postoperative intensive care unit stay and who were discharged from the hospital have a very poor long-term outcome and even worse quality of life. These data lead to a consideration of the wisdom of using heroic treatment in patients who face a prolonged postoperative intensive care unit stay in view of the dismal clinical results and enormous use of hospital and human resources. Our objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (>10 days) postoperative stay in the intensive care unit and were discharged from the hospital. Among 3125 consecutive patients who underwent cardiac operations in a 5-year period, we prospectively identified 57 who faced a prolonged postoperative intensive care unit stay and were discharged alive from the hospital. Patients were enrolled in a prospective follow-up protocol and evaluated every 6 to 12 months both clinically and instrumentally. Mean intensive care unit stay was 34 ± 9 days (range 11–141 days). Follow-up was complete and mean follow-up time was 71 months. Overall survival was 12 (21%) of 57, and the majority of follow-up deaths were cardiac related. Of the surviving patients, only a small minority (4/12) regained full autonomy and returned to their previous lifestyle. Risk factors for prolonged intensive care unit stay were age, New York Heart Association/Canadian Cardiovascular Society class, hypertension, diabetes, low ejection fraction, aortic surgery, preoperative renal failure, nonelective surgery, prolonged cardiopulmonary bypass time, and perioperative use of aortic counterpulsator. Patients who face a prolonged postoperative intensive care unit stay and who were discharged from the hospital have a very poor long-term outcome and even worse quality of life. These data lead to a consideration of the wisdom of using heroic treatment in patients who face a prolonged postoperative intensive care unit stay in view of the dismal clinical results and enormous use of hospital and human resources. Objective Our objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (>10 days) postoperative stay in the intensive care unit and were discharged from the hospital. Methods Among 3125 consecutive patients who underwent cardiac operations in a 5-year period, we prospectively identified 57 who faced a prolonged postoperative intensive care unit stay and were discharged alive from the hospital. Patients were enrolled in a prospective follow-up protocol and evaluated every 6 to 12 months both clinically and instrumentally. Results Mean intensive care unit stay was 34 ± 9 days (range 11–141 days). Follow-up was complete and mean follow-up time was 71 months. Overall survival was 12 (21%) of 57, and the majority of follow-up deaths were cardiac related. Of the surviving patients, only a small minority (4/12) regained full autonomy and returned to their previous lifestyle. Risk factors for prolonged intensive care unit stay were age, New York Heart Association/Canadian Cardiovascular Society class, hypertension, diabetes, low ejection fraction, aortic surgery, preoperative renal failure, nonelective surgery, prolonged cardiopulmonary bypass time, and perioperative use of aortic counterpulsator. Conclusions Patients who face a prolonged postoperative intensive care unit stay and who were discharged from the hospital have a very poor long-term outcome and even worse quality of life. These data lead to a consideration of the wisdom of using heroic treatment in patients who face a prolonged postoperative intensive care unit stay in view of the dismal clinical results and enormous use of hospital and human resources. OBJECTIVEOur objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (>10 days) postoperative stay in the intensive care unit and were discharged from the hospital.METHODSAmong 3125 consecutive patients who underwent cardiac operations in a 5-year period, we prospectively identified 57 who faced a prolonged postoperative intensive care unit stay and were discharged alive from the hospital. Patients were enrolled in a prospective follow-up protocol and evaluated every 6 to 12 months both clinically and instrumentally.RESULTSMean intensive care unit stay was 34 +/- 9 days (range 11-141 days). Follow-up was complete and mean follow-up time was 71 months. Overall survival was 12 (21%) of 57, and the majority of follow-up deaths were cardiac related. Of the surviving patients, only a small minority (4/12) regained full autonomy and returned to their previous lifestyle. Risk factors for prolonged intensive care unit stay were age, New York Heart Association/Canadian Cardiovascular Society class, hypertension, diabetes, low ejection fraction, aortic surgery, preoperative renal failure, nonelective surgery, prolonged cardiopulmonary bypass time, and perioperative use of aortic counterpulsator.CONCLUSIONSPatients who face a prolonged postoperative intensive care unit stay and who were discharged from the hospital have a very poor long-term outcome and even worse quality of life. These data lead to a consideration of the wisdom of using heroic treatment in patients who face a prolonged postoperative intensive care unit stay in view of the dismal clinical results and enormous use of hospital and human resources. |
Author | Girola, Fabiana Schiavello, Rocco Martinelli, Lorenzo Della Vella, Carmine Piscitelli, Mariantonietta Anselmi, Amedeo Possati, Gianfederico Gaudino, Mario |
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References_xml | – volume: 20 start-page: 212 year: 2005 end-page: 217 ident: bib2 article-title: Survival and quality of life of cardiac surgery complicated by prolonged Intensive Care publication-title: J Card Surg contributor: fullname: Ibrahim – volume: 15 start-page: 816 year: 1999 end-page: 822 ident: bib4 article-title: Risk factors and outcome in European cardiac surgery: analysis of the Euro-SCORE multinational database of 19,030 patients publication-title: Eur J Cardiothorac Surg contributor: fullname: Baudet – volume: 73 start-page: 1472 year: 2002 end-page: 1478 ident: bib1 article-title: Long-term survival and quality of life in cardiac surgical patients with prolonged intensive care unit length of stay publication-title: Ann Thorac Surg contributor: fullname: Mahapatra – volume: 31 start-page: 1373 year: 2003 end-page: 1381 ident: bib5 article-title: Morbidity, mortality, and quality-of-life outcomes of patients requiring >or=14 days of mechanical ventilation publication-title: Crit Care Med contributor: fullname: Gibert – volume: 91 start-page: 936 year: 1999 end-page: 944 ident: bib7 article-title: Risk factors of delayed extubation, prolonged length of stay in the Intensive Care Unit, and mortality in patients undergoing coronary artery bypass graft with fast-track cardiac anesthesia publication-title: Anesthesiology contributor: fullname: Carroll-Munro – volume: 80 start-page: 1693 year: 2005 end-page: 1698 ident: bib6 article-title: Quality of life after heart valve surgery with prolonged intensive care publication-title: Ann Thorac Surg contributor: fullname: Stahle – volume: 344 start-page: 563 year: 1994 end-page: 570 ident: bib3 article-title: Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration publication-title: Lancet contributor: fullname: Kennedy – volume: 81 start-page: 880 year: 2006 end-page: 885 ident: bib8 article-title: Prolonged Intensiva Care Unit stay in cardiac surgery: risk factors and long-term survival publication-title: Ann Thorac Surg contributor: fullname: Spies – volume: 31 start-page: 1373 year: 2003 ident: 10.1016/j.jtcvs.2007.04.028_bib5 article-title: Morbidity, mortality, and quality-of-life outcomes of patients requiring >or=14 days of mechanical ventilation publication-title: Crit Care Med doi: 10.1097/01.CCM.0000065188.87029.C3 contributor: fullname: Combes – volume: 73 start-page: 1472 year: 2002 ident: 10.1016/j.jtcvs.2007.04.028_bib1 article-title: Long-term survival and quality of life in cardiac surgical patients with prolonged intensive care unit length of stay publication-title: Ann Thorac Surg doi: 10.1016/S0003-4975(02)03464-1 contributor: fullname: Williams – volume: 344 start-page: 563 year: 1994 ident: 10.1016/j.jtcvs.2007.04.028_bib3 article-title: Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration publication-title: Lancet doi: 10.1016/S0140-6736(94)91963-1 contributor: fullname: Yusuf – volume: 80 start-page: 1693 year: 2005 ident: 10.1016/j.jtcvs.2007.04.028_bib6 article-title: Quality of life after heart valve surgery with prolonged intensive care publication-title: Ann Thorac Surg doi: 10.1016/j.athoracsur.2005.04.042 contributor: fullname: Hellgren – volume: 20 start-page: 212 year: 2005 ident: 10.1016/j.jtcvs.2007.04.028_bib2 article-title: Survival and quality of life of cardiac surgery complicated by prolonged Intensive Care publication-title: J Card Surg doi: 10.1111/j.1540-8191.2005.200413.x contributor: fullname: Bapat – volume: 91 start-page: 936 year: 1999 ident: 10.1016/j.jtcvs.2007.04.028_bib7 article-title: Risk factors of delayed extubation, prolonged length of stay in the Intensive Care Unit, and mortality in patients undergoing coronary artery bypass graft with fast-track cardiac anesthesia publication-title: Anesthesiology doi: 10.1097/00000542-199910000-00012 contributor: fullname: Wong – volume: 15 start-page: 816 year: 1999 ident: 10.1016/j.jtcvs.2007.04.028_bib4 article-title: Risk factors and outcome in European cardiac surgery: analysis of the Euro-SCORE multinational database of 19,030 patients publication-title: Eur J Cardiothorac Surg doi: 10.1016/S1010-7940(99)00106-2 contributor: fullname: Roques – volume: 81 start-page: 880 year: 2006 ident: 10.1016/j.jtcvs.2007.04.028_bib8 article-title: Prolonged Intensiva Care Unit stay in cardiac surgery: risk factors and long-term survival publication-title: Ann Thorac Surg doi: 10.1016/j.athoracsur.2005.09.077 contributor: fullname: Hein |
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Snippet | Objective Our objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (>10 days) postoperative stay in the... Our objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (>10 days) postoperative stay in the intensive care... OBJECTIVEOur objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (>10 days) postoperative stay in the... |
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SubjectTerms | Activities of Daily Living Aged Biological and medical sciences Cardiac Surgical Procedures Cardiothoracic Surgery Comorbidity Female Follow-Up Studies Health Services Research Hospital Mortality Humans Intensive Care Units - statistics & numerical data Intensive Care Units - utilization Length of Stay - statistics & numerical data Logistic Models Male Medical sciences Prospective Studies Quality of Life Risk Factors Severity of Illness Index Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Survival Rate |
Title | Long-term survival and quality of life of patients with prolonged postoperative intensive care unit stay: Unmasking an apparent success |
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